SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001093772 |
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Gene Symbol: | KIT |
Description: | Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), transcript variant 1, mRNA. |
Gene Location: | chr4(+):55524094-55606881 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54738722C>T | COSN6834893 | RK119_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-425-5p |
tttTGTCATTagccaccat |
0 | AAUGACAC | m7a | (m6a->m7a) | NA | NA | No effect | |
hsa-miR-4502 |
ttttgTCATCAGCcaccat |
11 |
GCUGAUGA | m8a | Disrupted | -0.218000 | -0.126000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54738754T>C | COSN9792384 | C0012T | [kidney][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-let-7f-2-3p |
ttccaaCTGTATAtattcc |
6 |
CUAUACAG | m7b | Disrupted | -0.164000 | -0.027000 |
1.190000 |
|
hsa-miR-1185-1-3p |
ttccaaCTGTATATattcc |
6 |
AUAUACAG | m8a | Disrupted | -0.183000 | -0.046000 |
0.430000 |
|
hsa-miR-1185-2-3p |
ttccaaCTGTATATattcc |
6 |
AUAUACAG | m8a | Disrupted | -0.173000 | -0.036000 |
0.050000 |
|
hsa-miR-5011-5p |
ttccaactgTATATATtcc |
13 |
UAUAUAUA | m7b | (m7b->m6c) | 0.070000 | 0.022000 |
3.320000 |
|
hsa-miR-582-5p |
ttccAACTGTAtatattcc |
9 |
UUACAGUU | m7b | Disrupted | -0.136000 | no TS |
2.810000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54738793G>A | cosmic_v64_1760544 | Leukemia/T-ALL | |||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-129-5p |
ccatgaaCAAAAAacattc |
0 | CUUUUUGC | m6b | Created | 0.091 | 0.131 |
-2.83 |
|
hsa-miR-26b-3p |
ccatGAACAGaaaacattc |
0 | CCUGUUCU | m6b | Disrupted | -0.105 | no TS | No effect | |
hsa-miR-375 |
ccatGAACAAAaaacattc |
0 | UUUGUUCG | m7a | Created | -0.081 | -0.164 |
-0.16 |
|
hsa-miR-4652-3p |
ccatgAACAGAAaacattc |
0 | GUUCUGUU | m7b | Disrupted | -0.256 | -0.102 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54739212C>A | COSN2033963 | RK027_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1321 |
aaggCCTCCCTagccagca |
0 | CAGGGAGG | m7b | Disrupted | -0.181000 | no TS |
2.300000 |
|
hsa-miR-149-3p |
aaggCCTCCCTagccagca |
0 | AGGGAGGG | m7a | Disrupted | NA | NA |
0.030000 |
|
hsa-miR-3162-5p |
aaggcCTCCCTAgccagca |
0 | UUAGGGAG | m7b | Disrupted | -0.027000 | no TS | No effect | |
hsa-miR-4443 |
aagGCCTCCAtagccagca |
0 | UUGGAGGC | m7b | (m6b->m7b) | no TS | -0.144000 |
-0.590000 |
|
hsa-miR-4739 |
aaggCCTCCCTagccagca |
0 | AAGGGAGG | m7b | Disrupted | -0.170000 | no TS |
0.010000 |
|
hsa-miR-4756-5p |
aaggCCTCCCTagccagca |
0 | CAGGGAGG | m7b | Disrupted | -0.244000 | no TS |
5.040000 |
|
hsa-miR-4802-5p |
aaggCCTCCATAgccagca |
0 | UAUGGAGG | m8a | Created | no TS | -0.185000 |
-0.900000 |
|
hsa-miR-1321 |
aaggCCTCCCTagccagca |
0 | CAGGGAGG | m7b | Disrupted | -0.181 | no TS |
2.3 |
|
hsa-miR-149-3p |
aaggCCTCCCTagccagca |
0 | AGGGAGGG | m7a | Disrupted | NA | NA |
0.03 |
|
hsa-miR-3162-5p |
aaggcCTCCCTAgccagca |
0 | UUAGGGAG | m7b | Disrupted | -0.027 | no TS | No effect | |
hsa-miR-4443 |
aagGCCTCCAtagccagca |
0 | UUGGAGGC | m7b | (m6b->m7b) | no TS | -0.144 |
-0.59 |
|
hsa-miR-4739 |
aaggCCTCCCTagccagca |
0 | AAGGGAGG | m7b | Disrupted | -0.17 | no TS |
0.01 |
|
hsa-miR-4756-5p |
aaggCCTCCCTagccagca |
0 | CAGGGAGG | m7b | Disrupted | -0.244 | no TS |
5.04 |
|
hsa-miR-4802-5p |
aaggCCTCCATAgccagca |
0 | UAUGGAGG | m8a | Created | no TS | -0.185 |
-0.9 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54739408G>T | COSN7640469 | PCSI_0164_Pa_P_526 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4698 |
caaagcaCATTTTGAacaa |
0 | UCAAAAUG | m8a | Created | no TS | 0.052000 |
-0.420000 |
|
hsa-miR-5008-3p |
caaAGCACAGtttgaacaa |
5 |
CCUGUGCU | m7b | (m7b->m6b) | -0.170000 | no TS | No effect | |
hsa-miR-548g-3p |
caaagcACAGTTTgaacaa |
1 |
AAAACUGU | m7b | Disrupted | 0.001000 | no TS |
0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54739442T>G | COSN7640470 | PCSI_0218_Pa_P_526 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-148a-5p |
ctgatGAACTTattctgta |
3 |
AAAGUUCU | m6b | Disrupted | 0.002000 | no TS | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54739468C>A | COSN9045057 | AOCS-131-1-3 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54739641A>G | cosmic_v64_1760522 | Leukemia/T-ALL | |||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4783-3p |
gtcctggaCACCGGGccag |
0 | CCCCGGUG | m7b | Disrupted | -0.179 | no TS |
0.54 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54739819G>C | COSN9045058 | AOCS-094-1-1 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-671-5p |
ttaccagaaGCTTCCatag |
0 | AGGAAGCC | m6b | Disrupted | -0.575000 | -0.512000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54740088C>A | COSN2033964 | RK182_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3941 |
aaaTGTGTAAatggcagag |
16 |
UUACACAC | m7a | (m6a->m7a) | -0.186000 | -0.206000 |
-0.020000 |
|
hsa-miR-4659a-5p |
aaatgtgtaCATGGCAGag |
5 |
CUGCCAUG | m8a | (m8a->m7b) | -0.151000 | no TS |
0.342000 |
|
hsa-miR-4659b-5p |
aaatgtgtaCATGGCAgag |
5 |
UUGCCAUG | m7b | (m7b->m6c) | -0.151000 | no TS |
0.350000 |
|
hsa-miR-4672 |
aaaTGTGTAAatggcagag |
16 |
UUACACAG | m7a | (m6a->m7a) | -0.254000 | -0.272000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54740256G>T | COSN8491134 | J80_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr4:g.54740257G>T | COSN8491135 | J80_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-21-3p |
agatttTGGTGTTGtgttg |
6 |
CAACACCA | m8a | Created | -0.176000 | -0.335000 |
-0.020000 |
|
hsa-miR-3591-3p |
agatttTGGTGTTgtgttg |
6 |
AAACACCA | m7b | Created | -0.167000 | -0.317000 |
-1.770000 |
|
hsa-miR-5003-5p |
agattttggTGTTGTGttg |
0 | UCACAACA | m7b | (m6c->m7b) | no TS | -0.077000 |
-1.780000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr4:g.54740391A>G | cosmic_v64_1760535 | Leukemia/T-ALL | ||||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3616-5p |
gggCACTTCATtgagagtt |
10 |
AUGAAGUG | m8a | Disrupted | -0.19 | -0.086 |
0.15 |
hsa-miR-573 |
gggCACTTCAttgagagtt |
10 |
CUGAAGUG | m7b | (m7b->m6b) | -0.19 | -0.096 |
0.03 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
54739644 | rs144602457 | G | G |
hsa-miR-1538 hsa-miR-4745-3p hsa-miR-4783-3p |
5 5 2 |
gacaCCGGGCCAg gacaCCGGGCCAg gaCACCGGGccag |
Disrupted Disrupted Disrupted |
N N N |
-0.385 -0.417 -0.179 |
C |
hsa-miR-4743-5p |
9 |
gacacCCGGCCAg |
Created |
N |
-0.199 |
|||
54740081 | rs17084736 | A | A |
hsa-miR-3152-5p hsa-miR-4643 hsa-miR-466 hsa-miR-4774-3p hsa-miR-4789-3p |
2 11 11 2 11 |
AGGCAAAtgtgta aggcaaATGTGTA aggcaaATGTGTA AGGCAAAtgtgta aggcaaATGTGTA |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
-0.092 0.006 -0.047 -0.097 -0.002 |
G |
hsa-miR-216b-3p hsa-miR-329-3p hsa-miR-362-3p hsa-miR-3941 hsa-miR-603 |
3 11 11 11 8 |
aggcAAGTGTGta aggcaaGTGTGTA aggcaaGTGTGTA aggcaaGTGTGTA aggcaAGTGTGTA |
Created Created Created Created Created |
N N N N N |
-0.046 -0.042 -0.039 -0.074 -0.176 |
|||
54740391 | rs186953545 | A | A |
hsa-miR-3616-5p hsa-miR-4795-5p hsa-miR-573 |
10 10 10 |
CACTTCAttgaga CACTTCAttgaga CACTTCAttgaga |
Disrupted Disrupted Disrupted |
N N N |
-0.104 -0.076 -0.094 |
54740574 | rs115028437 | T | T |
hsa-miR-3163 hsa-miR-410-3p hsa-miR-5011-5p |
16 19 19 |
attTTTTATAtat attttTTATATAt atttttTATATAT |
Disrupted Disrupted Disrupted |
N N N |
0.039 -0.011 -0.144 |