SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_015656
Gene Symbol:	KIF26A
Description:	Homo sapiens kinesin family member 26A (KIF26A), mRNA.
Gene Location:	chr14(+):104605059-104647235
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr14:g.104179861G>T			COSN8588009		J76_T		[lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-5196-3p	agcGAGGATGtggtggggg	2	UCAUCCUC	m7b	(m7b->m6b)	-0.235000	-0.154000	2.890000

Mutation			Mutation ID		Sample Name		Cancer Type
chr14:g.104180887C>T			COSN6635273		CHC197T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-181a-3p	aagatgcaTCGATGGTtcc	0	ACCAUCGA	m8a	Disrupted	-0.325000	no TS	0.220000
hsa-miR-181c-3p	aagatgcatCGATGGTTcc	0	AACCAUCG	m8a	(m8a->m7b)	-0.270000	no TS	0.090000
hsa-miR-5700	aagATGCATTgatggttcc	0	UAAUGCAU	m7b	(m6b->m7b)	no TS	-0.147000	-1.200000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
104179855	rs141368140	G	G	hsa-miR-5196-3p	9	cggagcGAGGATG	Disrupted	N	-0.082
			A	hsa-miR-1915-5p hsa-miR-362-5p hsa-miR-500b-5p hsa-miR-502-5p hsa-miR-6772-3p hsa-miR-6841-3p	6 6 6 6 5 6	cggaGCAAGGAtg cggagCAAGGATg cggagCAAGGATg cggaGCAAGGAtg cGGAGCAAggatg cggaGCAAGGAtg	Created Created Created Created Created Created	N N N N N N	-0.102 -0.035 -0.035 -0.108 -0.124 -0.105
104180887	rs884996	C	C	hsa-miR-181a-3p hsa-miR-181c-3p	0	atgcaTCGATGGt atgcatCGATGGT	Disrupted Disrupted	N N	-0.325 -0.27
			T	hsa-miR-5700	2	ATGCATTgatggt	Created	N	-0.147

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