SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_020910
Gene Symbol: KIAA1549
Description: Homo sapiens KIAA1549 (KIAA1549), transcript variant 2, mRNA.
Gene Location: chr7(-):138516126-138666064
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr7:g.138831793G>A COSN4866605 tumor_4101316 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3692-5p aggttgctCAGCAGagctg
 2
 CCUGCUGG m6b Created -0.239000 -0.285000 No effect
hsa-miR-4663 aggttGCTCAGCagagctg
 0 AGCUGAGC m7b Created no TS -0.319000 -0.060000
hsa-miR-93-3p aggttgcTCAGCAGagctg
 5
 ACUGCUGA m7b Created 0.032000 -0.158000 -1.400000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138833400C>T COSN6353881 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-147b tccttctttCGCACAactt
 0 GUGUGCGG m6b Disrupted -0.083000 no TS 8.820000
hsa-miR-19a-3p tccttctTTTGCACAactt
 2
 UGUGCAAA m8a Created 0.045000 0.083000 -0.310000
hsa-miR-19b-3p tccttctTTTGCACAactt
 2
 UGUGCAAA m8a Created 0.049000 0.087000 -3.290000
hsa-miR-210 tccttctttCGCACAactt
 0 CUGUGCGU m6b Disrupted -0.079000 no TS 5.430000
hsa-miR-548aj-5p tccttCTTTTGCAcaactt
 1
 UGCAAAAG m8a Created 0.180000 0.297000 -0.070000
hsa-miR-548aw tccttcTTTTGCACaactt
 1
 GUGCAAAA m8a Created 0.165000 0.287000 -0.680000
hsa-miR-548g-5p tccttCTTTTGCAcaactt
 1
 UGCAAAAG m8a Created 0.180000 0.297000 -0.070000
hsa-miR-548x-5p tccttCTTTTGCAcaactt
 1
 UGCAAAAG m8a Created 0.180000 0.297000 -0.070000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138833437T>C COSN9924544 C0048T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4652-5p ataggAGTCCCCcgtttcc
 0 AGGGGACU m7b Created no TS -0.011000 -0.070000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138834127G>A COSN5096694 HX32T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3182 caccCAGAAGaagttgcat
 0 GCUUCUGU m6b Disrupted 0.230000 0.164000 No effect
hsa-miR-4659a-3p cacccAGAAGAAgttgcat
 0 UUUCUUCU m7b Disrupted 0.324000 0.156000 0.010000
hsa-miR-4659b-3p cacccAGAAGAAgttgcat
 0 UUUCUUCU m7b Disrupted 0.324000 0.156000 No effect
hsa-miR-4778-3p cacccaGAAGAAGttgcat
 2
 UCUUCUUC m7b Disrupted 0.099000 0.047000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138834213T>C ICGC_7E120C6E-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-122-5p gcaccactgCACTCCAacc
 0 UGGAGUGU m7a (m6a->m7a) -0.024 -0.007 No effect
hsa-miR-143-5p gcaccACTGCACtccaacc
 0 GGUGCAGU m7b Created -0.069 -0.023 No effect
hsa-miR-5693 gcaCCACTGCactccaacc
 0 GCAGUGGC m7a (m6b->m7a) -0.038 -0.038 No effect


Mutation Mutation ID Sample Name Cancer Type
chr7:g.138834248G>A COSN6353882 RK183_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr7:g.138834412T>C ICGC_A359D074-2A78-11E2-8335-12FD496BB9B8 CPCG_0102_Pr_P_P2 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-106a-5p atcccaGCACTTTgggagg
 0 AAAAGUGC m7b Created no TS 0.139 -0.01
hsa-miR-106b-5p atcccaGCACTTTgggagg
 0 UAAAGUGC m7b Created no TS 0.158 No effect
hsa-miR-17-5p atcccaGCACTTTGggagg
 0 CAAAGUGC m8a Created no TS 0.139 -0.01
hsa-miR-186-3p atcccagcaCTTTGGGagg
 0 GCCCAAAG m7b (m6b->m7b) 0.168 0.174 No effect
hsa-miR-20a-5p atcccaGCACTTTgggagg
 0 UAAAGUGC m7b Created no TS 0.149 -0.01
hsa-miR-20b-5p atcccaGCACTTTGggagg
 0 CAAAGUGC m8a Created no TS 0.149 -0.01
hsa-miR-302a-3p atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.138 0.011 No effect
hsa-miR-302b-3p atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.119 0.03 0.01
hsa-miR-302c-3p atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.11 0.039 No effect
hsa-miR-302d-3p atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.119 0.03 No effect
hsa-miR-302e atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.128 0.03 No effect
hsa-miR-372 atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.119 0.011 No effect
hsa-miR-373-3p atcccAGCACTTtgggagg
 0 GAAGUGCU m7b Created -0.156 -0.026 No effect
hsa-miR-4698 atcccagCATTTTGggagg
 0 UCAAAAUG m7b Disrupted 0.66 0.418 No effect
hsa-miR-512-3p atccCAGCACTTtgggagg
 0 AAGUGCUG m8a Created -0.184 -0.104 No effect
hsa-miR-519d atcccaGCACTTTGggagg
 0 CAAAGUGC m8a Created no TS 0.139 No effect
hsa-miR-520a-3p atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.138 0.011 No effect
hsa-miR-520b atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.128 0.002 No effect
hsa-miR-520c-3p atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.128 0.002 No effect
hsa-miR-520d-3p atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.138 0.011 No effect
hsa-miR-520e atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.147 0.002 No effect
hsa-miR-520g atcccagCACTTTGggagg
 0 ACAAAGUG m7b Created 0.161 0.357 No effect
hsa-miR-520h atcccagCACTTTGggagg
 0 ACAAAGUG m7b Created 0.161 0.357 No effect
hsa-miR-526b-3p atcccaGCACTTTgggagg
 0 GAAAGUGC m7b Created no TS 0.139 No effect
hsa-miR-93-5p atcccaGCACTTTGggagg
 0 CAAAGUGC m8a Created no TS 0.149 -0.02

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138834440G>A COSN6353883 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1271-3p agatCAGGCACggtggctc
 3
 AGUGCCUG m7b Created -0.244000 -0.255000 No effect
hsa-miR-550a-3-5p agatCAGGCACggtggctc
 3
 AGUGCCUG m7b Created -0.244000 -0.264000 -0.010000
hsa-miR-550a-5p agatCAGGCACggtggctc
 3
 AGUGCCUG m7b Created -0.244000 -0.264000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr7:g.138834623A>G COSN2204765 RK170_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr7:g.138834884C>T COSN14805133 8051712 [pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1207-5p gacctcCCCTGCCAcctcc
 3
 UGGCAGGG m8a Created 0.003000 -0.020000 -1.060000
hsa-miR-1908 gacctcCCCCGCCacctcc
 0 CGGCGGGG m7b Disrupted -0.142000 no TS 3.290000
hsa-miR-1909-3p gacctCCCCTGCcacctcc
 0 CGCAGGGG m7b Created no TS -0.034000 -0.610000
hsa-miR-4723-5p gacCTCCCCCgccacctcc
 3
 UGGGGGAG m7b (m7b->m6c) -0.074000 -0.096000 0.060000
hsa-miR-4736 gacctccCCTGCCacctcc
 3
 AGGCAGGU m6b Created -0.011000 -0.005000 -5.410000
hsa-miR-4763-3p gacctcCCCTGCCacctcc
 3
 AGGCAGGG m7b Created 0.013000 -0.010000 -3.430000
hsa-miR-5698 gacCTCCCCCgccacctcc
 3
 UGGGGGAG m7b (m7b->m6c) -0.083000 -0.096000 1.610000
hsa-miR-663a gacctcCCCCGCCacctcc
 0 AGGCGGGG m7b Disrupted -0.131000 no TS 1.780000
hsa-miR-1207-5p gacctcCCCTGCCAcctcc
 3
 UGGCAGGG m8a Created 0.003000 -0.020000 -1.060000
hsa-miR-1908 gacctcCCCCGCCacctcc
 0 CGGCGGGG m7b Disrupted -0.142000 no TS 3.290000
hsa-miR-1909-3p gacctCCCCTGCcacctcc
 0 CGCAGGGG m7b Created no TS -0.034000 -0.610000
hsa-miR-4723-5p gacCTCCCCCgccacctcc
 3
 UGGGGGAG m7b (m7b->m6c) -0.074000 -0.096000 0.060000
hsa-miR-4736 gacctccCCTGCCacctcc
 3
 AGGCAGGU m6b Created -0.011000 -0.005000 -5.410000
hsa-miR-4763-3p gacctcCCCTGCCacctcc
 3
 AGGCAGGG m7b Created 0.013000 -0.010000 -3.430000
hsa-miR-5698 gacCTCCCCCgccacctcc
 3
 UGGGGGAG m7b (m7b->m6c) -0.083000 -0.096000 1.610000
hsa-miR-663a gacctcCCCCGCCacctcc
 0 AGGCGGGG m7b Disrupted -0.131000 no TS 1.780000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138835131G>A COSN7963543 8031867 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-505-3p ggtccttgcGTTGACagcg
 2
 CGUCAACA m6b Disrupted 0.065000 no TS 0.900000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138835180G>T 9_4776 CRC-2-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548ao-3p accctagCGGTCTTcagac
 4
 AAAGACCG m7b Disrupted -0.039 -0.024 1.27

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138835310C>G COSN9924545 C0098T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-138-5p cccggatCACCAGCcctct
 4
 AGCUGGUG m7b Disrupted 0.026000 -0.003000 No effect
hsa-miR-4299 cccggaTCACCAGCcctct
 5
 GCUGGUGA m8a Disrupted -0.031000 -0.115000 -0.390000
hsa-miR-4492 cccggatcaCCAGCCCtct
 1
 GGGGCUGG m7b (m7b->m6b) -0.153000 -0.128000 No effect
hsa-miR-4498 cccggatcaCCAGCCCtct
 1
 UGGGCUGG m7b (m7b->m6b) -0.155000 -0.139000 -0.210000
hsa-miR-5001-5p cccggatcaCCAGCCCTct
 1
 AGGGCUGG m8a (m8a->m7a) -0.184000 -0.149000 No effect
hsa-miR-762 cccggatcaCCAGCCCtct
 1
 GGGGCUGG m7b (m7b->m6b) -0.199000 -0.118000 -0.060000
hsa-miR-93-3p cccggaTCAGCAGccctct
 5
 ACUGCUGA m7b Created 0.032000 0.140000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138835785T>A 0_287 Lung cancer
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3617 ttgATGTCTTggttttggt
 3
 AAAGACAU m7b (m7b->m6c) 0.235 0.105 No effect
hsa-miR-4305 ttgaTGTCTAGGttttggt
 3
 CCUAGACA m8a Created no TS -0.036 -0.05
hsa-miR-641 ttgATGTCTTggttttggt
 3
 AAAGACAU m7b (m7b->m6c) 0.256 0.145 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138837069C>A COSN2204766 RK209_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-147a gggCACACACaactcctgg
 1
 GUGUGUGG m7a (m7a->m6b) -0.001000 -0.033000 No effect
hsa-miR-2113 gggcaCACAAAactcctgg
 5
 AUUUGUGC m6b Created 0.037000 0.106000 No effect
hsa-miR-5010-3p gggcACACAAAActcctgg
 3
 UUUUGUGU m8a Created 0.030000 0.063000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138837307G>A COSN2204767 RK064_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1262 ccaTCACCCAcattcttcc
 1
 AUGGGUGA m7b (m6c->m7b) 0.065000 -0.102000 -0.500000
hsa-miR-299-3p ccatcaCCCACATtcttcc
 0 UAUGUGGG m7b Created no TS -0.146000 -0.320000
hsa-miR-3621 ccatcACCCGCattcttcc
 1
 CGCGGGUC m6b Disrupted -0.243000 no TS 13.180000
hsa-miR-3656 ccatCACCCGCattcttcc
 1
 GGCGGGUG m7b Disrupted -0.482000 no TS 3.790000
hsa-miR-4701-3p ccaTCACCCAcattcttcc
 1
 AUGGGUGA m7b (m6c->m7b) 0.056000 -0.111000 -0.960000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.138837352A>C COSN9832094 AOCS-137-1-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-382-3p agaaaccaAATGATaggtt
 0 AAUCAUUC m6b Disrupted 0.036000 no TS 0.260000
hsa-miR-4259 agaaaCCAACTGataggtt
 0 CAGUUGGG m7a Created NA NA -0.050000
hsa-miR-5002-5p agaaACCAAATgataggtt
 0 AAUUUGGU m7b Disrupted 0.224000 0.306000 3.010000
hsa-miR-5094 agaaaccaACTGATaggtt
 4
 AAUCAGUG m6b Created 0.035000 0.009000 No effect
hsa-miR-579 agaaacCAAATGAtaggtt
 0 UUCAUUUG m7b Disrupted 0.423000 0.429000 3.210000
hsa-miR-644b-3p agaaacCAAATGAtaggtt
 0 UUCAUUUG m7b Disrupted 0.413000 0.419000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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