SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001185097
Gene Symbol: INS
Description: Homo sapiens insulin (INS), transcript variant 1, mRNA.
Gene Location: chr11(-):2181008-2182439
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr11:g.2159809G>A COSN1080215 TCGA-BS-A0UV-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1250 tcctGCACCGagagagatg
 0 ACGGUGCU m6b Disrupted -0.224000 no TS 19.500000
hsa-miR-3615 tcctgcaCCGAGAGAgatg
 0 UCUCUCGG m8a Disrupted -0.517000 no TS 14.550000
hsa-miR-1250 tcctGCACCGagagagatg
 0 ACGGUGCU m6b Disrupted -0.224 no TS 19.5
hsa-miR-3615 tcctgcaCCGAGAGAgatg
 0 UCUCUCGG m8a Disrupted -0.517 no TS 14.55

Mutation Mutation ID Sample Name Cancer Type
chr11:g.2159842G>A COSN1080214 TCGA-AX-A0J0-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1587 acgCAGCCCAcaggcagcc
 0 UUGGGCUG m7b (m6c->m7b) no TS 0.000000 No effect
hsa-miR-4265 acgcaGCCCACAGgcagcc
 0 CUGUGGGC m8a Created no TS 0.000000 -1.630000
hsa-miR-4296 acgcaGCCCACAggcagcc
 0 AUGUGGGC m7b Created no TS 0.000000 -1.130000
hsa-miR-4322 acgcaGCCCACAGgcagcc
 0 CUGUGGGC m8a Created no TS 0.000000 -1.530000
hsa-miR-4417 acgcAGCCCACaggcagcc
 0 GGUGGGCU m7b Created no TS 0.000000 -0.330000
hsa-miR-4734 acgcagCCCGCAGgcagcc
 0 GCUGCGGG m7b Disrupted 0.000000 no TS No effect
hsa-miR-4763-5p acgcagcccGCAGGCagcc
 0 CGCCUGCC m6b Disrupted 0.000000 no TS No effect
hsa-miR-4767 acgcaGCCCGCaggcagcc
 0 CGCGGGCG m6b Disrupted 0.000000 no TS No effect
hsa-miR-1587 acgCAGCCCAcaggcagcc
 0 UUGGGCUG m7b (m6c->m7b) no TS 0 No effect
hsa-miR-4265 acgcaGCCCACAGgcagcc
 0 CUGUGGGC m8a Created no TS 0 -1.63
hsa-miR-4296 acgcaGCCCACAggcagcc
 0 AUGUGGGC m7b Created no TS 0 -1.13
hsa-miR-4322 acgcaGCCCACAGgcagcc
 0 CUGUGGGC m8a Created no TS 0 -1.53
hsa-miR-4417 acgcAGCCCACaggcagcc
 0 GGUGGGCU m7b Created no TS 0 -0.33
hsa-miR-4734 acgcagCCCGCAGgcagcc
 0 GCUGCGGG m7b Disrupted 0 no TS No effect
hsa-miR-4763-5p acgcagcccGCAGGCagcc
 0 CGCCUGCC m6b Disrupted 0 no TS No effect
hsa-miR-4767 acgcaGCCCGCaggcagcc
 0 CGCGGGCG m6b Disrupted 0 no TS No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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