SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001562
Gene Symbol: IL18
Description: Homo sapiens interleukin 18 (interferon-gamma-inducing factor) (IL18), transcript variant 2, mRNA.
Gene Location: chr11(-):112013975-112034840
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr11:g.112143314C>G ICGC_D2BE586C-2A78-11E2-951E-21FD496BB9B8 CPCG_0103_Pr_P_P5 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5691 gggcaacaAGAGCAAaact
0 UUGCUCUG m7a Created no TS -0.125 -2.81

Mutation Mutation ID Sample Name Cancer Type
chr11:g.112143329T>C ICGC_EB81B664-2A78-11E2-89D1-29FD496BB9B8 CPCG_0103_Pr_P_P8 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3135b attgcgCTCCAGCCtgggc
0 GGCUGGAG m8a Created no TS -0.162 -3.13
hsa-miR-3652 attgcgcTCCAGCCtgggc
0 CGGCUGGA m7b Created no TS -0.141 -3.02
hsa-miR-4430 attgcgcTCCAGCCTgggc
0 AGGCUGGA m8a Created no TS -0.141 -3.1

Mutation Mutation ID Sample Name Cancer Type
chr11:g.112143374C>A COSN1513992 RK079_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1203 acttgcaCTCCGGaggtag
0 CCCGGAGC m6b Disrupted -0.212000 no TS 8.990000
hsa-miR-454-3p acTTGCACTAcggaggtag
0 UAGUGCAA m8a (m7b->m8a) -0.078000 -0.240000 -0.330000
hsa-miR-4671-3p actTGCACTAcggaggtag
0 UUAGUGCA m7b (m6c->m7b) no TS -0.160000 -6.830000
hsa-miR-1203 acttgcaCTCCGGaggtag
0 CCCGGAGC m6b Disrupted -0.212 no TS 8.99
hsa-miR-454-3p acTTGCACTAcggaggtag
0 UAGUGCAA m8a (m7b->m8a) -0.078 -0.24 -0.33
hsa-miR-4671-3p actTGCACTAcggaggtag
0 UUAGUGCA m7b (m6c->m7b) no TS -0.16 -6.83

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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