SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
||||||||
Home | Search | Help | Download |
RefSeq ID: | NM_002188 |
---|---|
Gene Symbol: | IL13 |
Description: | Homo sapiens interleukin 13 (IL13), mRNA. |
Gene Location: | chr5(+):131993864-131996801 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr5:g.132660308G>A | COSN2070568 | RK092_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-450b-5p |
ttatTTGCAAAgacaggac |
0 | UUUUGCAA | m7b | Created | no TS | -0.134000 |
-0.070000 |
|
hsa-miR-4772-3p |
ttatTTGCAGagacaggac |
5 |
CCUGCAAC | m6b | Disrupted | -0.547000 | -0.425000 |
0.030000 |
|
hsa-miR-511 |
ttatttgcAAAGACAggac |
0 | GUGUCUUU | m7b | Created | no TS | -0.059000 |
-0.120000 |
|
hsa-miR-518a-5p |
ttaTTTGCAGagacaggac |
0 | CUGCAAAG | m7a | (m7a->m6a) | no TS | -0.092000 |
-0.120000 |
|
hsa-miR-527 |
ttaTTTGCAGagacaggac |
0 | CUGCAAAG | m7a | (m7a->m6a) | no TS | -0.092000 |
-0.120000 |
|
hsa-miR-593-3p |
ttatttgCAGAGACAggac |
3 |
UGUCUCUG | m8a | Disrupted | -0.436000 | -0.119000 |
5.510000 |
|
hsa-miR-450b-5p |
ttatTTGCAAAgacaggac |
0 | UUUUGCAA | m7b | Created | no TS | -0.134 |
-0.07 |
|
hsa-miR-4772-3p |
ttatTTGCAGagacaggac |
3 |
CCUGCAAC | m6b | Disrupted | -0.547 | -0.425 |
0.03 |
|
hsa-miR-511 |
ttatttgcAAAGACAggac |
0 | GUGUCUUU | m7b | Created | no TS | -0.059 |
-0.12 |
|
hsa-miR-518a-5p |
ttaTTTGCAGagacaggac |
0 | CUGCAAAG | m7a | (m7a->m6a) | no TS | -0.092 |
-0.12 |
|
hsa-miR-527 |
ttaTTTGCAGagacaggac |
0 | CUGCAAAG | m7a | (m7a->m6a) | no TS | -0.092 |
-0.12 |
|
hsa-miR-593-3p |
ttatttgCAGAGACAggac |
3 |
UGUCUCUG | m8a | Disrupted | -0.436 | -0.119 |
5.51 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr5:g.132660351C>G | COSN9925887 | C0069T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-2115-3p |
tttttctTTCTGATGtcaa |
1 |
CAUCAGAA | m8a | Disrupted | -0.159000 | no TS |
0.720000 |
hsa-miR-499a-3p |
tttttctttGTGATGTcaa |
0 | AACAUCAC | m7b | (m6c->m7b) | no TS | -0.241000 |
-4.030000 |
hsa-miR-499b-3p |
tttttctttGTGATGTcaa |
0 | AACAUCAC | m7b | (m6c->m7b) | no TS | -0.241000 |
1.140000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
132660333 | rs75868517 | G | G |
hsa-miR-2276-3p hsa-miR-4772-3p hsa-miR-891b |
6 5 5 |
gaagTTGCAGAtt gaaGTTGCAGAtt gAAGTTGCAgatt |
Disrupted Disrupted Disrupted |
N N N |
-0.147 -0.421 -0.381 |
A |
hsa-miR-3607-3p hsa-miR-3686 |
6 6 |
gaagTTACAGAtt gaagTTACAGAtt |
Created Created |
N N |
-0.097 -0.17 |
|||
132660337 | rs201863406 | A | A |
hsa-miR-2276-3p hsa-miR-4772-3p |
6 6 |
TTGCAGAttcatt TTGCAGAttcatt |
Disrupted Disrupted |
N N |
-0.15 -0.185 |
132660779 | rs200557616 | C | C |
hsa-miR-125a-5p hsa-miR-125b-5p hsa-miR-4319 hsa-miR-593-3p hsa-miR-627-5p hsa-miR-924 |
2 2 2 3 2 2 |
cagagaCTCAGGG cagagaCTCAGGG cagagaCTCAGGG CAGAGACtcaggg cagAGACTCAggg cagAGACTCAggg |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
-0.148 -0.157 -0.129 -0.119 -0.066 -0.067 |
T |
hsa-miR-216b-5p hsa-miR-3140-5p hsa-miR-345-3p hsa-miR-5187-3p |
3 2 2 2 |
cAGAGATTcaggg cagagATTCAGGg cagagaTTCAGGG cagaGATTCAGgg |
Created Created Created Created |
N N N N |
0.013 -0.017 -0.089 -0.038 |