SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001111284 |
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Gene Symbol: | IGF1 |
Description: | Homo sapiens insulin-like growth factor 1 (somatomedin C) (IGF1), transcript variant 4, mRNA. |
Gene Location: | chr12(-):102789644-102872429 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102396577A>G | COSN10096273 | C0035T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-155-3p |
taaaGTAGGAaaaataaaa |
0 | CUCCUACA | m6b | Disrupted | -0.124000 | no TS |
0.070000 |
hsa-miR-3162-3p |
taaaGTAGGGAaaataaaa |
0 | UCCCUACC | m7a | Created | -0.063000 | -0.226000 | No effect |
hsa-miR-3685 |
taaaGTAGGAAAaataaaa |
0 | UUUCCUAC | m8a | Disrupted | -0.244000 | no TS |
0.330000 |
hsa-miR-384 |
taaagTAGGAAaaataaaa |
0 | AUUCCUAG | m6b | Disrupted | -0.057000 | 0.002000 | No effect |
hsa-miR-4446-5p |
taaagtAGGGAAAataaaa |
3 |
AUUUCCCU | m7b | Created | 0.002000 | -0.188000 | No effect |
hsa-miR-4755-5p |
taaagtAGGGAAAataaaa |
0 | UUUCCCUU | m7a | Created | no TS | -0.063000 | No effect |
hsa-miR-5006-3p |
taaagtAGGGAAAataaaa |
0 | UUUCCCUU | m7a | Created | no TS | -0.076000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102396804A>T | COSN8691912 | AOCS-056-1-X | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-302b-5p |
cttttTTAAAGTaaaaaaa |
0 | ACUUUAAC | m7a | Disrupted | 0.134000 | 0.134000 |
0.020000 |
hsa-miR-302d-5p |
cttttTTAAAGTaaaaaaa |
0 | ACUUUAAC | m7a | Disrupted | 0.138000 | 0.138000 |
0.010000 |
hsa-miR-323a-3p |
ctttttTAATGTaaaaaaa |
2 |
CACAUUAC | m6b | Created | 0.082000 | 0.096000 |
-0.060000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102397170G>T | COSN8691913 | AOCS-108-1-7 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-508-5p |
cccaggCTGGAGTgcagtg |
2 |
UACUCCAG | m7b | Disrupted | -0.037000 | -0.143000 | No effect |
hsa-miR-766-3p |
cccagGCTGGAGTgcagtg |
2 |
ACUCCAGC | m8a | Disrupted | -0.123000 | -0.162000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102397714A>G | COSN4726349 | tumor_4102009 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1915-5p |
cccttGCAAGGaccataaa |
6 |
ACCUUGCC | m6b | Created | -0.036000 | -0.018000 | No effect |
hsa-miR-450b-5p |
cccTTGCAAAgaccataaa |
0 | UUUUGCAA | m7b | (m7b->m6c) | 0.289000 | 0.098000 | No effect |
hsa-miR-502-5p |
cccttGCAAGGAccataaa |
6 |
AUCCUUGC | m7b | Created | -0.108000 | -0.121000 |
-0.220000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102398103G>T | COSN8585171 | J9_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102398336A>T | COSN15429276 | AOCS-150-8-X | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4450 |
ttctgccaAATCCCCcttg |
2 |
UGGGGAUU | m7b | Disrupted | -0.127000 | -0.059000 |
2.280000 |
hsa-miR-4525 |
ttctgccaaATCCCCCttg |
2 |
GGGGGGAU | m7b | (m7b->m6b) | -0.505000 | -0.419000 |
0.030000 |
hsa-miR-5010-5p |
ttctgccaaATCCCCCTtg |
2 |
AGGGGGAU | m8a | (m8a->m7a) | -0.541000 | -0.417000 |
-1.160000 |
hsa-miR-625-5p |
ttctgccaaTTCCCCCTtg |
2 |
AGGGGGAA | m8a | (m7a->m8a) | -0.553000 | -0.625000 |
0.030000 |
hsa-miR-4450 |
ttctgccaAATCCCCcttg |
2 |
UGGGGAUU | m7b | Disrupted | -0.127000 | -0.059000 |
2.280000 |
hsa-miR-4525 |
ttctgccaaATCCCCCttg |
2 |
GGGGGGAU | m7b | (m7b->m6b) | -0.505000 | -0.419000 |
0.030000 |
hsa-miR-5010-5p |
ttctgccaaATCCCCCTtg |
2 |
AGGGGGAU | m8a | (m8a->m7a) | -0.541000 | -0.417000 |
-1.160000 |
hsa-miR-625-5p |
ttctgccaaTTCCCCCTtg |
2 |
AGGGGGAA | m8a | (m7a->m8a) | -0.553000 | -0.625000 |
0.030000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102399806T>G | COSN4726350 | tumor_4116738 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][diffuse_large_B_cell_lymphoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-298 |
taggcagtCTTCTGCagac |
10 |
AGCAGAAG | m7b | Disrupted | 0.085000 | 0.039000 | No effect |
hsa-miR-3166 |
taggcagtcGTCTGCagac |
0 | CGCAGACA | m6b | Created | no TS | -0.028000 |
-3.870000 |
hsa-miR-4771 |
taggcagtcGTCTGCagac |
0 | AGCAGACU | m6b | Created | no TS | -0.034000 |
-0.400000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102400585C>G | COSN10096274 | C0057T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-545-5p |
aacTTTACTGttattctta |
1 |
UCAGUAAA | m7b | (m6c->m7b) | -0.102000 | -0.075000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102401314G>A | COSN8959782 | SS6003317 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-587 |
ctcATGGAAAaaatgaaca |
4 |
UUUCCAUA | m7a | (m6b->m7a) | 0.072000 | 0.102000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102401339G>A | COSN1140934 | HCC29T | [liver][NS][carcinoma][hepatocellular_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1288 |
attttaGCAGTCCtggttt |
0 | UGGACUGC | m7b | Disrupted | -0.207000 | -0.034000 |
0.010000 |
hsa-miR-3169 |
attttagCAGTCCTggttt |
3 |
UAGGACUG | m7b | Disrupted | -0.052000 | no TS |
0.340000 |
hsa-miR-1288 |
attttaGCAGTCCtggttt |
0 | UGGACUGC | m7b | Disrupted | -0.207 | -0.034 |
0.01 |
hsa-miR-3169 |
attttagCAGTCCTggttt |
0 | UAGGACUG | m7b | Disrupted | -0.052 | no TS |
0.34 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102401779A>T | COSN8585172 | J52_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3924 |
tatgttttATACATAgaaa |
7 |
AUAUGUAU | m7b | Created | 0.136000 | 0.074000 | No effect |
hsa-miR-4307 |
tatgttttAAACATagaaa |
0 | AAUGUUUU | m6b | Disrupted | 0.293000 | 0.246000 | No effect |
hsa-miR-568 |
tatgttTTATACATagaaa |
0 | AUGUAUAA | m8a | Created | -0.010000 | -0.097000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102401988G>A | COSN1140935 | HX13T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-10a-3p |
atatttgcCGAATTTGgcc |
0 | CAAAUUCG | m8a | Disrupted | 0.231000 | 0.191000 |
0.100000 |
hsa-miR-1271-5p |
atattTGCCAAatttggcc |
2 |
CUUGGCAC | m6b | Created | 0.019000 | -0.092000 |
-0.010000 |
hsa-miR-182-5p |
atatTTGCCAAAtttggcc |
2 |
UUUGGCAA | m8a | Created | 0.027000 | -0.227000 |
0.280000 |
hsa-miR-4470 |
ataTTTGCCAaatttggcc |
0 | UGGCAAAC | m7a | (m6b->m7a) | no TS | -0.096000 |
0.530000 |
hsa-miR-10a-3p |
atatttgcCGAATTTGgcc |
0 | CAAAUUCG | m8a | Disrupted | 0.231 | 0.191 |
0.1 |
hsa-miR-1271-5p |
atattTGCCAAatttggcc |
0 | CUUGGCAC | m6b | Created | 0.019 | -0.092 |
-0.01 |
hsa-miR-182-5p |
atatTTGCCAAAtttggcc |
0 | UUUGGCAA | m8a | Created | 0.027 | -0.227 |
0.28 |
hsa-miR-4470 |
ataTTTGCCAaatttggcc |
0 | UGGCAAAC | m7a | (m6b->m7a) | no TS | -0.096 |
0.53 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102402255G>A | COSN1140936 | BN40T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102402262T>C | COSN5314334 | RK169_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-20b-3p |
aatgttCTACAGaaaagaa |
5 |
ACUGUAGU | m6b | Created | -0.003000 | -0.152000 | No effect |
hsa-miR-3137 |
aatgttCTACAGAaaagaa |
0 | UCUGUAGC | m7a | Created | no TS | -0.158000 | No effect |
hsa-miR-3686 |
aatgttcTACAGAaaagaa |
7 |
AUCUGUAA | m6b | Created | -0.089000 | -0.212000 | No effect |
hsa-miR-4482-3p |
aatgttctATAGAAAagaa |
10 |
UUUCUAUU | m7a | Disrupted | 0.332000 | 0.375000 | No effect |
hsa-miR-4652-3p |
aatgttctACAGAAaagaa |
0 | GUUCUGUU | m6b | Created | 0.027000 | -0.062000 |
-0.020000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.102402397T>C | COSN9032266 | 8051720 | [pancreas][NS][carcinoid-endocrine_tumour][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-595 |
ttgataACACTTaaaagat |
7 |
GAAGUGUG | m6b | Created | -0.295000 | -0.396000 |
-0.180000 |