SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
	Home	Search	Help	Download

Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_001098479
Gene Symbol:	HLA-F
Description:	Homo sapiens major histocompatibility complex, class I, F (HLA-F), transcript variant 3, mRNA.
Gene Location:	chr6(+):29691116-29695073
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr6:g.29727224C>A			COSN14805446		8051712		[pancreas][NS][carcinoid-endocrine_tumour][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-183-3p	cactaaaTAATTCAtcaca	0	GUGAAUUA	m7b	Created	no TS	-0.111000	-4.380000
hsa-miR-548ao-5p	cactaaaTACTTCatcaca	2	AGAAGUAA	m6b	Disrupted	-0.104000	no TS	9.270000
hsa-miR-548ax	cactaaaTACTTCatcaca	2	AGAAGUAA	m6b	Disrupted	-0.104000	no TS	12.910000
hsa-miR-944	cactaAATAATTcatcaca	3	AAAUUAUU	m7b	Created	-0.080000	-0.100000	-0.320000
hsa-miR-183-3p	cactaaaTAATTCAtcaca	0	GUGAAUUA	m7b	Created	no TS	-0.111000	-4.380000
hsa-miR-548ao-5p	cactaaaTACTTCatcaca	2	AGAAGUAA	m6b	Disrupted	-0.104000	no TS	9.270000
hsa-miR-548ax	cactaaaTACTTCatcaca	2	AGAAGUAA	m6b	Disrupted	-0.104000	no TS	12.910000
hsa-miR-944	cactaAATAATTcatcaca	3	AAAUUAUU	m7b	Created	-0.080000	-0.100000	-0.320000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
29727279	rs200044686	A	A	hsa-miR-944	3	aaaataAATAATT	Disrupted	N	-0.08
			C	hsa-miR-3924	2	aaaATACATAAtt	Created	N	-0.276

Genome Browser