SomamiR DB

SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only All 6mer or longer seed matches

PolymiRTS Database

RefSeq ID:	NM_002124
Gene Symbol:	HLA-DRB1
Description:	Homo sapiens major histocompatibility complex, class II, DR beta 1 (HLA-DRB1), transcript variant 2, mRNA.
Gene Location:	chr6(-):32546546-32557562
Browse Associations
Browse Pathways

Mutation			Mutation ID		Sample Name		Cancer Type
chr6:g.32578926T>C			9_58967		CRC-6-Tumor		Colorectal adenocarcinoma
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-185-3p	ttcctCAGCCCCTgccctt	4	AGGGGCUG	m8a	Created	no TS	-0.209	-2.58
hsa-miR-1909-3p	ttcctcagCCCCTGCcctt	4	CGCAGGGG	m7b	Created	no TS	-0.174	-2.64
hsa-miR-28-5p	ttcctcAGCTCCTgccctt	4	AAGGAGCU	m7b	Disrupted	-0.106	no TS	4.17
hsa-miR-3139	ttcctcAGCTCCTgccctt	4	UAGGAGCU	m7b	Disrupted	-0.115	no TS	6.53
hsa-miR-3160-3p	ttccTCAGCTCctgccctt	5	AGAGCUGA	m7b	Disrupted	-0.103	no TS	4.76
hsa-miR-4656	ttccTCAGCCCctgccctt	5	UGGGCUGA	m7b	Created	no TS	-0.139	-2.72
hsa-miR-4722-5p	ttcctcagCTCCTGCCctt	4	GGCAGGAG	m8a	Disrupted	-0.145	no TS	0.01
hsa-miR-708-5p	ttcctcAGCTCCTgccctt	4	AAGGAGCU	m7b	Disrupted	-0.106	no TS	5.99

Mutation			Mutation ID		Sample Name		Cancer Type
chr6:g.32578981G>A			0_257				Prostate cancer
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

Mutation			Mutation ID		Sample Name		Cancer Type
chr6:g.32579041G>A			COSN167736		GC8_T		[stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1298	gctttgcaGAATGAAaagc	0	UUCAUUCG	m7a	Created	no TS	-0.066000	-0.020000
hsa-miR-2276	gctTTGCAGAatgaaaagc	0	UCUGCAAG	m7a	(m6b->m7a)	no TS	-0.095000	-3.030000
hsa-miR-4772-3p	gctTTGCAGGatgaaaagc	0	CCUGCAAC	m7a	(m7a->m6b)	no TS	-0.087000	-3.030000
hsa-miR-4793-5p	gctttgCAGGATGaaaagc	2	ACAUCCUG	m7b	Disrupted	-0.383000	no TS	3.570000
hsa-miR-5196-3p	gctttgcAGGATGAaaagc	2	UCAUCCUC	m7a	Disrupted	-0.121000	no TS	-4.410000
hsa-miR-544a	gcttTGCAGAATgaaaagc	2	AUUCUGCA	m8a	Created	-0.232000	-0.411000	-3.270000
hsa-miR-1298	gctttgcaGAATGAAaagc	0	UUCAUUCG	m7a	Created	no TS	-0.066	-0.02
hsa-miR-2276	gctTTGCAGAatgaaaagc	0	UCUGCAAG	m7a	(m6b->m7a)	no TS	-0.095	-3.03
hsa-miR-4772-3p	gctTTGCAGGatgaaaagc	0	CCUGCAAC	m7a	(m7a->m6b)	no TS	-0.087	-3.03
hsa-miR-4793-5p	gctttgCAGGATGaaaagc	0	ACAUCCUG	m7b	Disrupted	-0.383	no TS	3.57
hsa-miR-5196-3p	gctttgcAGGATGAaaagc	0	UCAUCCUC	m7a	Disrupted	-0.121	no TS	-4.41
hsa-miR-544a	gcttTGCAGAATgaaaagc	0	AUUCUGCA	m8a	Created	-0.232	-0.411	-3.27

Mutation			Mutation ID		Sample Name		Cancer Type
chr6:g.32579051G>A			COSN167737		GC8_T		[stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-320a	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071000	-0.010000
hsa-miR-320b	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071000	-0.010000
hsa-miR-320c	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071000	-0.040000
hsa-miR-320d	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071000	-0.360000
hsa-miR-320e	ttctgccCCAGCTTTgcag	0	AAAGCUGG	m8a	Created	no TS	-0.182000	-0.100000
hsa-miR-4429	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071000	-0.010000
hsa-miR-4731-5p	ttctgCCCCAGCtttgcag	2	UGCUGGGG	m7b	Created	-0.143000	-0.381000	No effect
hsa-miR-486-3p	ttCTGCCCCGgctttgcag	2	CGGGGCAG	m8a	(m8a->m7b)	-0.286000	-0.522000	No effect
hsa-miR-5090	ttcTGCCCCGGctttgcag	0	CCGGGGCA	m8a	Disrupted	-0.311000	no TS	1.960000
hsa-miR-320a	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071	-0.01
hsa-miR-320b	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071	-0.01
hsa-miR-320c	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071	-0.04
hsa-miR-320d	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071	-0.36
hsa-miR-320e	ttctgccCCAGCTTTgcag	0	AAAGCUGG	m8a	Created	no TS	-0.182	-0.1
hsa-miR-4429	ttctgcccCAGCTTTgcag	0	AAAAGCUG	m7b	Created	no TS	-0.071	-0.01
hsa-miR-4731-5p	ttctgCCCCAGCtttgcag	0	UGCUGGGG	m7b	Created	-0.143	-0.381	No effect
hsa-miR-486-3p	ttCTGCCCCGgctttgcag	0	CGGGGCAG	m8a	(m8a->m7b)	-0.286	-0.522	No effect
hsa-miR-5090	ttcTGCCCCGGctttgcag	0	CCGGGGCA	m8a	Disrupted	-0.311	no TS	1.96

Mutation			Mutation ID		Sample Name		Cancer Type
chr6:g.32579055C>T			COSN167738		GC8_T		[stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-486-3p	aactttCTGCCCCGgcttt	2	CGGGGCAG	m8a	Disrupted	-0.286000	no TS	0.070000
hsa-miR-5090	aactttcTGCCCCGGcttt	0	CCGGGGCA	m8a	Disrupted	-0.311000	no TS	1.230000
hsa-miR-486-3p	aactttCTGCCCCGgcttt	0	CGGGGCAG	m8a	Disrupted	-0.286	no TS	0.07
hsa-miR-5090	aactttcTGCCCCGGcttt	0	CCGGGGCA	m8a	Disrupted	-0.311	no TS	1.23

Mutation			Mutation ID		Sample Name		Cancer Type
chr6:g.32579061T>C			COSN167739		GC8_T		[stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-148a-5p	aggaAGAACTTTctgcccc	0	AAAGUUCU	m8a	Disrupted	-0.088000	no TS	4.350000
hsa-miR-22-5p	agGAAGAACTttctgcccc	3	AGUUCUUC	m8a	(m8a->m7b)	-0.137000	-0.109000	1.100000
hsa-miR-298	aggaagaacCTTCTGCccc	0	AGCAGAAG	m7b	(m6b->m7b)	no TS	-0.090000	No effect
hsa-miR-5584-3p	aggAAGAACTttctgcccc	0	UAGUUCUU	m7b	(m7b->m6c)	-0.099000	no TS	1.070000
hsa-miR-148a-5p	aggaAGAACTTTctgcccc	0	AAAGUUCU	m8a	Disrupted	-0.088	no TS	4.35
hsa-miR-22-5p	agGAAGAACTttctgcccc	0	AGUUCUUC	m8a	(m8a->m7b)	-0.137	-0.109	1.1
hsa-miR-298	aggaagaacCTTCTGCccc	0	AGCAGAAG	m7b	(m6b->m7b)	no TS	-0.09	No effect
hsa-miR-5584-3p	aggAAGAACTttctgcccc	0	UAGUUCUU	m7b	(m7b->m6c)	-0.099	no TS	1.07

Mutation			Mutation ID		Sample Name		Cancer Type
chr6:g.32579076C>-			ICGC_ssm_v2_14276		HX5T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-133a	agatGACCAAttcaagga	0	UUUGGUCC	m6b	Created	NA	NA	No effect
hsa-miR-133b	agatGACCAAttcaagga	0	UUUGGUCC	m6b	Created	NA	NA	No effect
hsa-miR-183-3p	agatgaccAATTCAagga	0	GUGAAUUA	m6b	Created	no TS	0.000000	No effect
hsa-miR-4452	agatgaccAATTCAAgga	0	UUGAAUUC	m7a	Created	no TS	0.000000	No effect

**Germline mutations in target sites of miRNAs in somatic mutation table**
Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
32578900	rs1060190	A	A	hsa-miR-4731-5p hsa-miR-5589-5p	2 2	CCCAGCAttgatg CCCAGCAttgatg	Disrupted Disrupted	N N	-0.143 -0.153
32578900	rs1060190	A	T	hsa-miR-320a hsa-miR-320b hsa-miR-320c hsa-miR-320d hsa-miR-320e hsa-miR-330-3p hsa-miR-4429	2 2 2 2 2 2 2	ccCAGCTTTgatg ccCAGCTTTgatg ccCAGCTTTgatg ccCAGCTTTgatg cCCAGCTTtgatg cccaGCTTTGAtg ccCAGCTTTgatg	Created Created Created Created Created Created Created	N N N N N N N	-0.045 -0.045 -0.045 -0.045 -0.138 -0.03 -0.055
32578900	rs113493811	-	-	hsa-miR-4731-5p hsa-miR-5589-5p	2 2	tCCCAGCAttgatgg tCCCAGCAttgatgg	Unknown Unknown	N N	-0.143 -0.153
32578900	rs113493811	-	CA	hsa-miR-3652 hsa-miR-4430 hsa-miR-4505 hsa-miR-5787 hsa-miR-647 hsa-miR-6842-3p	2 2 2 2 2 2	tcCCAGCCAattgatgg tcCCAGCCAattgatgg tCCCAGCCAattgatgg tCCCAGCCAattgatgg tccCAGCCAAttgatgg tcCCAGCCAAttgatgg	Unknown Unknown Unknown Unknown Unknown Unknown	N N N N N N	-0.17 -0.167 -0.442 -0.452 -0.153 -0.369
32578903	rs71685135	-	-	hsa-miR-3199 hsa-miR-365a-5p hsa-miR-365b-5p hsa-miR-4731-5p hsa-miR-5589-5p hsa-miR-8052	2 2 2 2 2 2	aAGTCCCAgcattga AAGTCCCAgcattga AAGTCCCAgcattga aagtCCCAGCAttga aagtCCCAGCAttga aAGTCCCAgcattga	Unknown Unknown Unknown Unknown Unknown Unknown	N N N N N N	-0.123 -0.158 -0.158 -0.143 -0.153 -0.134
32578903	rs71685135	-	CA	hsa-miR-2110 hsa-miR-3144-5p hsa-miR-3150a-3p hsa-miR-3191-3p hsa-miR-450a-2-3p hsa-miR-4652-5p hsa-miR-6763-5p hsa-miR-6810-5p hsa-miR-6857-5p	2 3 2 3 2 2 2 2 2	aagTCCCCAAgcattga aaGTCCCCAagcattga aagTCCCCAAgcattga aaGTCCCCAagcattga aagTCCCCAAgcattga aAGTCCCCAagcattga aagTCCCCAAgcattga aaGTCCCCAAgcattga aagTCCCCAAgcattga	Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown	N N N N N N N N N	-0.144 -0.185 -0.132 -0.206 -0.132 -0.42 -0.132 -0.42 -0.175
32578904	rs35306263	-	-	hsa-miR-3199 hsa-miR-365a-5p hsa-miR-365b-5p hsa-miR-5589-5p hsa-miR-8052	2 2 2 2 2	gaAGTCCCAgcattg gAAGTCCCAgcattg gAAGTCCCAgcattg gaagtCCCAGCAttg gaAGTCCCAgcattg	Unknown Unknown Unknown Unknown Unknown	N N N N N	-0.123 -0.185 -0.185 0.004 -0.134
32578904	rs35306263	-	CC	hsa-miR-1275 hsa-miR-4525 hsa-miR-4652-5p hsa-miR-4665-5p hsa-miR-4723-5p hsa-miR-4731-5p hsa-miR-5010-5p hsa-miR-5698 hsa-miR-625-5p hsa-miR-637 hsa-miR-6870-5p hsa-miR-7111-5p	2 2 2 2 2 2 2 2 2 2 2 2	gaagTCCCCCAgcattg gaagTCCCCCAgcattg gaAGTCCCCcagcattg gaagTCCCCCAgcattg gaagTCCCCCAgcattg gaagtcCCCCAGCAttg gaagTCCCCCAgcattg gaagTCCCCCAgcattg gaagTCCCCCAgcattg gaagtCCCCCAGcattg gaagTCCCCCAgcattg gaagTCCCCCAgcattg	Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown	N N N N N N N N N N N N	-0.178 -0.185 -0.202 -0.178 -0.174 -0.256 -0.185 -0.174 -0.175 -0.253 -0.174 -0.184
32578905	rs35195677	C	C	hsa-miR-3199 hsa-miR-365a-5p hsa-miR-365b-5p hsa-miR-4731-5p hsa-miR-5589-5p hsa-miR-8052	2 2 2 6 6 2	gaAGTCCCAgcat gAAGTCCCAgcat gAAGTCCCAgcat gaagtCCCAGCAt gaagtCCCAGCAt gaAGTCCCAgcat	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N	-0.123 -0.324 -0.324 -0.143 -0.153 -0.134
32578905	rs35195677	C	A	hsa-miR-134-5p hsa-miR-3118 hsa-miR-3164 hsa-miR-617 hsa-miR-6505-3p hsa-miR-6820-3p	2 2 2 2 2 2	gaAGTCACAgcat gaAGTCACAgcat gAAGTCACAgcat GAAGTCAcagcat GAAGTCAcagcat gAAGTCACAgcat	Created Created Created Created Created Created	N N N N N N	-0.085 -0.075 -0.208 -0.069 -0.053 -0.208
32578907	rs1060185	T	T	hsa-miR-3199 hsa-miR-365a-5p hsa-miR-365b-5p hsa-miR-8052	2 2 2 2	ctgaAGTCCCAgc ctgAAGTCCCAgc ctgAAGTCCCAgc ctgaAGTCCCAgc	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.123 -0.324 -0.324 -0.134
32578907	rs1060185	T	C	hsa-miR-185-3p hsa-miR-4283 hsa-miR-4489 hsa-miR-4731-5p	2 2 2 5	ctgaAGCCCCAgc ctgaAGCCCCAgc ctgaAGCCCCAgc ctgaagCCCCAGC	Created Created Created Created	N N N N	-0.145 -0.154 -0.167 -0.256
32578921	rs1064709	C	C	hsa-miR-4436b-3p hsa-miR-4632-5p hsa-miR-4722-5p hsa-miR-6721-5p hsa-miR-6735-5p hsa-miR-6879-5p hsa-miR-7843-5p	2 2 2 2 2 2 2	ctcCTGCCCTtgg ctcCTGCCCTtgg CTCCTGCccttgg ctCCTGCCCttgg ctcCTGCCCTtgg ctcCTGCCCTtgg ctcCTGCCCTtgg	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N	-0.142 -0.142 -0.145 -0.209 -0.161 -0.142 -0.17
32578921	rs1064709	C	T	hsa-miR-8080	2	ctccTGTCCTTgg	Created	N	-0.042
32578922	rs3200047	G	G	hsa-miR-4436b-3p hsa-miR-4632-5p hsa-miR-4722-5p hsa-miR-6721-5p hsa-miR-6735-5p hsa-miR-6879-5p hsa-miR-7843-5p	2 2 2 2 2 2 2	gctcCTGCCCTtg gctcCTGCCCTtg gCTCCTGCccttg gctCCTGCCCttg gctcCTGCCCTtg gctcCTGCCCTtg gctcCTGCCCTtg	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N	-0.142 -0.142 -0.145 -0.209 -0.161 -0.142 -0.17
32578922	rs3200047	G	A	hsa-miR-28-5p hsa-miR-3139 hsa-miR-6755-5p hsa-miR-708-5p	2 2 2 2	GCTCCTAcccttg GCTCCTAcccttg gctcCTACCCTtg GCTCCTAcccttg	Created Created Created Created	N N N N	-0.188 -0.189 -0.177 -0.188
32578924	rs35000099	C	C	hsa-miR-28-5p hsa-miR-3139 hsa-miR-4436b-3p hsa-miR-4632-5p hsa-miR-4722-5p hsa-miR-6721-5p hsa-miR-6735-5p hsa-miR-6879-5p hsa-miR-708-5p hsa-miR-7843-5p	2 2 2 2 2 2 2 2 2 2	cAGCTCCTgccct cAGCTCCTgccct cagctcCTGCCCT cagctcCTGCCCT cagCTCCTGCcct cagctCCTGCCCt cagctcCTGCCCT cagctcCTGCCCT cAGCTCCTgccct cagctcCTGCCCT	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N N N N	-0.106 -0.115 -0.142 -0.142 -0.145 -0.209 -0.161 -0.142 -0.106 -0.17
32578924	rs35000099	C
32578926	rs113804375	T	T	hsa-miR-28-5p hsa-miR-3139 hsa-miR-3160-3p hsa-miR-4722-5p hsa-miR-708-5p	2 2 2 2 2	ctcAGCTCCTgcc ctcAGCTCCTgcc cTCAGCTCctgcc ctcagCTCCTGCc ctcAGCTCCTgcc	Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N	-0.106 -0.115 -0.103 -0.145 -0.106
32578926	rs113804375	T	C	hsa-miR-1207-5p hsa-miR-185-3p hsa-miR-1909-3p hsa-miR-4656 hsa-miR-4763-3p hsa-miR-6085 hsa-miR-6722-3p hsa-miR-6813-5p	1 2 2 2 1 2 2 2	ctcagcCCCTGCC ctCAGCCCCtgcc ctcagCCCCTGCc cTCAGCCCctgcc ctcagcCCCTGCC ctcAGCCCCTgcc ctcagCCCCTGCc ctcAGCCCCTgcc	Created Created Created Created Created Created Created Created	N N N N N N N N	-0.179 -0.209 -0.174 -0.139 -0.16 -0.172 -0.174 -0.144
32578930	rs35716402	C	C	hsa-miR-3160-3p hsa-miR-3915 hsa-miR-3928-3p hsa-miR-7160-5p	2 5 5 6	cttccTCAGCTCc cTTCCTCAgctcc cTTCCTCAgctcc cttCCTCAGCtcc	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.103 -0.038 -0.055 -0.167
32578930	rs35716402	C	T	hsa-miR-4521 hsa-miR-4633-3p hsa-miR-610 hsa-miR-6500-5p hsa-miR-651-3p	6 2 2 2 5	ctTCCTTAGctcc cttcctTAGCTCC cttccTTAGCTCc cttcctTAGCTCC cTTCCTTAgctcc	Created Created Created Created Created	N N N N N	-0.103 -0.173 -0.087 -0.183 0.031
32578959	rs148582499	-	-	hsa-miR-1184 hsa-miR-1205 hsa-miR-17-3p hsa-miR-544a hsa-miR-6738-3p	2 2 2 2 2	ggcaaCTGCAGAaaa ggcaaCTGCAGAaaa ggcaACTGCAGAaaa ggcaacTGCAGAAAa ggcaactGCAGAAAa	Unknown Unknown Unknown Unknown Unknown	N N N N N	0.001 0.002 -0.219 0.009 0.002
32578959	rs148582499	-	CT	hsa-miR-2467-3p hsa-miR-3158-5p hsa-miR-3678-3p	2 2 2	ggcaaCTCTGCAgaaaa ggcaacTCTGCAGAaaa ggcaaCTCTGCAgaaaa	Unknown Unknown Unknown	N N N	-0.106 -0.196 -0.189
32579041	rs36217730	G	G	hsa-miR-4793-5p hsa-miR-5196-3p	2 2	ttgCAGGATGAaa ttgcAGGATGAaa	Disrupted Disrupted	N N	-0.383 -0.121
32579041	rs36217730	G	A	hsa-miR-1298-5p hsa-miR-2276-3p hsa-miR-4772-3p hsa-miR-544a	2 2 2 2	ttgcaGAATGAAa TTGCAGAatgaaa TTGCAGAatgaaa tTGCAGAAtgaaa	Created Created Created Created	N N N N	-0.066 -0.095 -0.087 -0.179
32579042	rs35324556	G	G	hsa-miR-4793-5p hsa-miR-5196-3p	2 2	tttgCAGGATGAa tttgcAGGATGAa	Disrupted Disrupted	N N	-0.383 -0.121
32579042	rs35324556	G	A	hsa-miR-452-3p hsa-miR-518a-5p hsa-miR-527 hsa-miR-548aw	2 2 2 2	tttgcaAGATGAA TTTGCAAgatgaa TTTGCAAgatgaa TTTGCAAgatgaa	Created Created Created Created	N N N N	-0.076 -0.144 -0.144 -0.024
32579044	rs146292738	C	C	hsa-miR-4793-5p hsa-miR-518a-5p hsa-miR-527	2 2 2	gctttgCAGGATG gCTTTGCAggatg gCTTTGCAggatg	Disrupted Disrupted Disrupted	N N N	-0.257 -0.045 -0.045
32579044	rs146292738	C	A	hsa-miR-205-5p hsa-miR-330-3p	2 2	gcttTGAAGGAtg GCTTTGAaggatg	Created Created	N N	-0.12 -0.064
32579051	rs1064697	A	G	hsa-miR-5090 hsa-miR-6775-5p hsa-miR-6784-5p	0	TGCCCCGgctttg TGCCCCGgctttg tGCCCCGGctttg	Created Created Created	N N N	-0.311 -0.302 -0.392
32579051	rs1064697	A	A	hsa-miR-320a hsa-miR-320b hsa-miR-320c hsa-miR-320d hsa-miR-320e hsa-miR-4429 hsa-miR-4731-5p hsa-miR-486-3p	0	tgcccCAGCTTTg tgcccCAGCTTTg tgcccCAGCTTTg tgcccCAGCTTTg tgccCCAGCTTtg tgcccCAGCTTTg tgCCCCAGCtttg TGCCCCAgctttg	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N N	-0.071 -0.071 -0.071 -0.071 -0.182 -0.071 -0.238 -0.236
32579055	rs36217728	C	C	hsa-miR-486-3p hsa-miR-5090 hsa-miR-6775-5p hsa-miR-6784-5p	2 0 0 0	tttCTGCCCCggc tttcTGCCCCGgc tttcTGCCCCGgc tttctGCCCCGGc	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.286 -0.311 -0.302 -0.392
32579055	rs36217728	C
32579059	rs200538592	T
32579059	rs200538592	T	A	hsa-miR-148a-5p	0	GAACTTActgccc	Created	N	-0.111
32579061	rs1064694	C	T	hsa-miR-148a-5p hsa-miR-5584-3p	0	aAGAACTTtctgc AAGAACTttctgc	Created Created	N N	-0.088 -0.099
32579061	rs1064694	C	C	hsa-miR-298	0	aagaacCTTCTGC	Disrupted	N	-0.09
32579062	rs1064692	C	C	hsa-miR-148a-5p hsa-miR-22-5p hsa-miR-5584-3p	0	gaAGAACTTtctg GAAGAACtttctg gAAGAACTttctg	Disrupted Disrupted Disrupted	N N N	-0.088 -0.137 -0.099
32579062	rs1064692	C
32579065	rs201375698	G	G	hsa-miR-148a-5p hsa-miR-22-5p hsa-miR-5584-3p hsa-miR-6875-3p	0	aaggaAGAACTTt aagGAAGAACttt aaggAAGAACTtt aaGGAAGAActtt	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.088 -0.137 -0.099 -0.17
32579065	rs201375698	G	A	hsa-miR-561-3p	0	aaggaaAAACTTT	Created	N	-0.089
32579066	rs202053852	A	A	hsa-miR-148a-5p hsa-miR-22-5p hsa-miR-502-5p hsa-miR-5584-3p hsa-miR-6875-3p	0	caaggaAGAACTT caagGAAGAACtt CAAGGAAgaactt caaggAAGAACTt caaGGAAGAActt	Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N	-0.088 -0.137 -0.13 -0.099 -0.17
32579066	rs202053852	A	G	hsa-miR-4326 hsa-miR-4691-5p hsa-miR-5193 hsa-miR-660-3p hsa-miR-6749-3p hsa-miR-6792-3p	3 4 4 4 4 4	caagGAGGAACtt caaGGAGGAActt caAGGAGGAactt caAGGAGGAactt caaGGAGGAActt caaGGAGGAActt	Created Created Created Created Created Created	N N N N N N	-0.182 -0.172 -0.169 -0.153 -0.166 -0.165
32579076	rs41285181	-	C		0
32579076	rs41285181	-	-	hsa-miR-183-3p hsa-miR-219a-2-3p hsa-miR-219b-3p hsa-miR-4452 hsa-miR-5587-5p	2 2 2 2 2	tgaccAATTCAA tgacCAATTCAa tgacCAATTCAa tgaccAATTCAA TGACCAAttcaa	Unknown Unknown Unknown Unknown Unknown	N N N N N	No Change No Change No Change No Change No Change
32579076	rs71822874	-	C		0
32579076	rs71822874	-	-	hsa-miR-183-3p hsa-miR-219a-2-3p hsa-miR-219b-3p hsa-miR-4452 hsa-miR-5587-5p	2 2 2 2 2	tgaccAATTCAA tgacCAATTCAa tgacCAATTCAa tgaccAATTCAA TGACCAAttcaa	Unknown Unknown Unknown Unknown Unknown	N N N N N	No Change No Change No Change No Change No Change

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Somatic mutations that impact miRNA target sites

Germline mutations in target sites of miRNAs in somatic mutation table

Genome Browser