SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001243042
Gene Symbol: HLA-C
Description: Homo sapiens major histocompatibility complex, class I, C (HLA-C), transcript variant 2, mRNA.
Gene Location: chr6(-):31236525-31239913
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr6:g.31268906G>- ICGC_ssm_v3_129682 HCC65T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-148a-3p aaattcatgTGCACTGAg
 0 UCAGUGCA m8a (m7a->m8a) -0.331000 -0.354000 -0.750000
hsa-miR-148b-3p aaattcatgTGCACTGAg
 0 UCAGUGCA m8a (m7a->m8a) -0.331000 -0.354000 1.150000
hsa-miR-152 aaattcatgTGCACTGAg
 0 UCAGUGCA m8a (m7a->m8a) -0.331000 -0.354000 -2.060000
hsa-miR-5589-3p aaattCATGTGCActgag
 0 UGCACAUG m8a Created no TS -0.360000 -11.870000
hsa-miR-767-5p aaattcATGGTGCActgag
 0 UGCACCAU m8a Disrupted -0.367000 no TS 12.640000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.31269059T>C COSN5087188 HCC61T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-211-3p tgtctgcGTCCCTGttagc
 0 GCAGGGAC m7b Created no TS -0.190000 -1.850000
hsa-miR-873-5p tgtctgcGTTCCTGttagc
 0 GCAGGAAC m7b Disrupted -0.145000 no TS 0.030000
hsa-miR-211-3p tgtctgcGTCCCTGttagc
 0 GCAGGGAC m7b Created no TS -0.190000 -1.850000
hsa-miR-873-5p tgtctgcGTTCCTGttagc
 0 GCAGGAAC m7b Disrupted -0.145000 no TS 0.030000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.31269123C>T COSN524034 TCGA-A2-A04X-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4428 ttcacaccTCTCCTTtgtg
 0 CAAGGAGA m7b Disrupted -0.126000 no TS 1.890000
hsa-miR-4428 ttcacaccTCTCCTTtgtg
 0 CAAGGAGA m7b Disrupted -0.126000 no TS 1.890000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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