SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_139006 |
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Gene Symbol: | HFE |
Description: | Homo sapiens hemochromatosis (HFE), transcript variant 1, mRNA. |
Gene Location: | chr6(+):26087508-26095469 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr6:g.26094619C>T | COSN4954927 | SS6003308 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1915-3p |
agctttgaaCCCTGGGacg |
1 |
CCCCAGGG | m7b | (m7b->m6c) | -0.396000 | -0.133000 |
0.220000 |
hsa-miR-4685-5p |
agctttgaaCCCTGGGacg |
2 |
CCCAGGGC | m7a | (m7a->m6b) | -0.153000 | -0.153000 |
0.020000 |
hsa-miR-1915-3p |
agctttgaaCCCTGGGacg |
1 |
CCCCAGGG | m7b | (m7b->m6c) | -0.396000 | -0.133000 |
0.220000 |
hsa-miR-4685-5p |
agctttgaaCCCTGGGacg |
2 |
CCCAGGGC | m7a | (m7a->m6b) | -0.153000 | -0.153000 |
0.020000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr6:g.26094698C>A | COSN5086718 | HCC154 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-105-5p |
caacttttCATTTGAatcc |
0 | UCAAAUGC | m7a | Created | no TS | 0.000000 |
-9.020000 |
hsa-miR-3646 |
caacttTTCATTTgaatcc |
0 | AAAAUGAA | m7b | Created | 0.114000 | 0.128000 |
-0.030000 |
hsa-miR-3671 |
caacttttcATTTGAatcc |
0 | AUCAAAUA | m6b | Created | no TS | 0.032000 |
-9.470000 |
hsa-miR-607 |
caacttttcATTTGAAtcc |
0 | GUUCAAAU | m7b | (m6c->m7b) | no TS | 0.064000 |
0.330000 |
hsa-miR-105-5p |
caacttttCATTTGAatcc |
0 | UCAAAUGC | m7a | Created | no TS | 0.000000 |
-9.020000 |
hsa-miR-3646 |
caacttTTCATTTgaatcc |
0 | AAAAUGAA | m7b | Created | 0.114000 | 0.128000 |
-0.030000 |
hsa-miR-3671 |
caacttttcATTTGAatcc |
0 | AUCAAAUA | m6b | Created | no TS | 0.032000 |
-9.470000 |
hsa-miR-607 |
caacttttcATTTGAAtcc |
0 | GUUCAAAU | m7b | (m6c->m7b) | no TS | 0.064000 |
0.330000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr6:g.26094891A>C | COSN1330288 | BN37T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3145-3p |
gtaggaggcAAATATCTtg |
2 |
AGAUAUUU | m8a | (m8a->m7b) | 0.036000 | no TS |
0.010000 |
hsa-miR-3152-5p |
gtagGAGGCAAatatcttg |
2 |
AUUGCCUC | m7b | Disrupted | -0.356000 | no TS |
7.860000 |
hsa-miR-4757-5p |
gtagGAGGCCaatatcttg |
0 | AGGCCUCU | m6b | Created | no TS | -0.186000 |
-6.640000 |
hsa-miR-4774-3p |
gtaggAGGCAAatatcttg |
2 |
AUUGCCUA | m6b | Disrupted | -0.125000 | no TS |
9.660000 |
hsa-miR-3145-3p |
gtaggaggcAAATATCTtg |
0 | AGAUAUUU | m8a | (m8a->m7b) | 0.036 | no TS |
0.01 |
hsa-miR-3152-5p |
gtagGAGGCAAatatcttg |
2 |
AUUGCCUC | m7b | Disrupted | -0.356 | no TS |
7.86 |
hsa-miR-4757-5p |
gtagGAGGCCaatatcttg |
0 | AGGCCUCU | m6b | Created | no TS | -0.186 |
-6.64 |
hsa-miR-4774-3p |
gtaggAGGCAAatatcttg |
2 |
AUUGCCUA | m6b | Disrupted | -0.125 | no TS |
9.66 |