SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_138426
Gene Symbol: GLCCI1
Description: Homo sapiens glucocorticoid induced transcript 1 (GLCCI1), mRNA.
Gene Location: chr7(+):8008422-8128709
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr7:g.8086564A>C COSN5274065 SNUH_G47_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr7:g.8086579G>A COSN14634895 PCSI_0181_Pa_X [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4273 catggattcAGAACAagat
 0 GUGUUCUC m6b Created no TS -0.098000 -1.550000
hsa-miR-4427 catggATTCAGAacaagat
 13
 UCUGAAUA m7a Created -0.040000 -0.100000 No effect
hsa-miR-4680-3p catggATTCAGAacaagat
 1
 UCUGAAUU m7a Created -0.111000 -0.165000 No effect
hsa-miR-5187-3p catgGATTCAGaacaagat
 0 ACUGAAUC m7b Created no TS -0.246000 -0.060000
hsa-miR-4273 catggattcAGAACAagat
 0 GUGUUCUC m6b Created no TS -0.098000 -1.550000
hsa-miR-4427 catggATTCAGAacaagat
 13
 UCUGAAUA m7a Created -0.040000 -0.100000 No effect
hsa-miR-4680-3p catggATTCAGAacaagat
 1
 UCUGAAUU m7a Created -0.111000 -0.165000 No effect
hsa-miR-5187-3p catgGATTCAGaacaagat
 0 ACUGAAUC m7b Created no TS -0.246000 -0.060000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.8087686T>G COSN9772009 C0089T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3646 tgcatgatcTTCATTTaca
 0 AAAAUGAA m7b (m7b->m6c) 0.317000 0.251000 -0.010000
hsa-miR-4699-5p tgcatgATCTTCatttaca
 2
 AGAAGAUU m6b Disrupted 0.009000 no TS 0.170000
hsa-miR-5694 tgcATGATCTtcatttaca
 2
 CAGAUCAU m7b (m7b->m6b) -0.035000 -0.055000 0.050000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.8087742T>G COSN1354174 HX4T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3613-3p aggtTTTTTTGgtgactta
 10
 ACAAAAAA m7b Disrupted 0.321000 0.384000 0.010000
hsa-miR-3613-3p aggtTTTTTTGgtgactta
 0 ACAAAAAA m7b Disrupted 0.321 0.384 0.01

Mutation Mutation ID Sample Name Cancer Type
chr7:g.8087908G>C COSN195749 PD4199a [NS][NS][NS][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1236 gtgtGAAGAGagccccagg
 9
 CCUCUUCC m6b Disrupted 0.064000 no TS 0.220000
hsa-miR-185-3p gtgtgaagaCAGCCCCagg
 0 AGGGGCUG m7b (m6c->m7b) -0.066000 -0.200000 -4.120000
hsa-miR-4283 gtgtgaagaGAGCCCCAgg
 0 UGGGGCUC m8a (m8a->m7b) -0.218000 -0.075000 0.010000
hsa-miR-4492 gtgtgaagaCAGCCCCagg
 0 GGGGCUGG m7a (m6b->m7a) NA NA No effect
hsa-miR-4675 gtgtgaagACAGCCCCagg
 0 GGGGCUGU m8a Created no TS -0.047000 -1.860000
hsa-miR-4741 gtgtgaagACAGCCCcagg
 0 CGGGCUGU m7b Created no TS -0.029000 -5.210000
hsa-miR-626 gtgtgaAGACAGCcccagg
 0 AGCUGUCU m7b Created no TS -0.039000 -1.940000
hsa-miR-762 gtgtgaagaCAGCCCCagg
 0 GGGGCUGG m7a (m6b->m7a) NA NA No effect
hsa-miR-1236 gtgtGAAGAGagccccagg
 9
 CCUCUUCC m6b Disrupted 0.064 no TS 0.22
hsa-miR-185-3p gtgtgaagaCAGCCCCagg
 0 AGGGGCUG m7b (m6c->m7b) -0.066 -0.2 -4.12
hsa-miR-4283 gtgtgaagaGAGCCCCAgg
 0 UGGGGCUC m8a (m8a->m7b) -0.218 -0.075 0.01
hsa-miR-4492 gtgtgaagaCAGCCCCagg
 0 GGGGCUGG m7a (m6b->m7a) NA NA No effect
hsa-miR-4675 gtgtgaagACAGCCCCagg
 0 GGGGCUGU m8a Created no TS -0.047 -1.86
hsa-miR-4741 gtgtgaagACAGCCCcagg
 0 CGGGCUGU m7b Created no TS -0.029 -4.02
hsa-miR-626 gtgtgaAGACAGCcccagg
 0 AGCUGUCU m7b Created no TS -0.039 -1.94
hsa-miR-762 gtgtgaagaCAGCCCCagg
 0 GGGGCUGG m7a (m6b->m7a) NA NA No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.8088035T>C COSN4872260 tumor_4134005 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-549 tagAGTTGTCtcatctgcg
 0 UGACAACU m7b (m6b->m7b) no TS -0.017000 -2.090000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.8088286T>G COSN5103780 HX29T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4803 gtgcaTTATGTTgtcatga
 18
 UAACAUAA m7b Created 0.036000 0.085000 -2.380000
hsa-miR-5692a gtgcATTATTTtgtcatga
 19
 CAAAUAAU m7b Disrupted 0.147000 0.017000 0.240000

Mutation Mutation ID Sample Name Cancer Type
chr7:g.8088539G>A COSN6893409 RK200_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-204-5p gttAAAGGGAgaaaattac
 0 UUCCCUUU m7b (m6b->m7b) no TS -0.162000 -0.020000
hsa-miR-211-5p gttAAAGGGAgaaaattac
 0 UUCCCUUU m7b (m6b->m7b) no TS -0.162000 -0.070000
hsa-miR-3679-3p gttaaaGGGGGAAaattac
 0 CUUCCCCC m7b Disrupted -0.467000 no TS 0.500000
hsa-miR-4287 gttaAAGGGAGAaaattac
 0 UCUCCCUU m8a Created no TS -0.342000 No effect
hsa-miR-4446-5p gttaaaggGGGAAAattac
 0 AUUUCCCU m6b Disrupted -0.073000 no TS No effect
hsa-miR-4469 gttaaAGGGAGaaaattac
 0 GCUCCCUC m6b Created no TS -0.143000 No effect
hsa-miR-4685-3p gttaAAGGGAGAaaattac
 0 UCUCCCUU m8a Created no TS -0.342000 -0.910000
hsa-miR-4713-5p gttaaaGGGAGAAaattac
 0 UUCUCCCA m7a Created -0.077000 -0.245000 No effect
hsa-miR-629-3p gttaaaGGGAGAAaattac
 0 GUUCUCCC m7b Created no TS -0.366000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr7:g.8088556G>A 9_16017 CRC-3-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3688-3p actagTTCCATAagataaa
 13
 UAUGGAAA m7a Created no TS -0.055 No effect
hsa-miR-4788 actagtTCCGTAAgataaa
 13
 UUACGGAC m7a Disrupted -0.203 no TS No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
8087539 rs138213171 A A hsa-miR-4803
3
 ttgtTTATGTTAg
 Disrupted
N
 0.099
8087757 rs115138837 G G hsa-miR-137
hsa-miR-5691
hsa-miR-6805-3p
6
3
3
 acaagAGCAATAg
acaAGAGCAAtag
acaAGAGCAAtag
 Disrupted
Disrupted
Disrupted
N
N
N
 0.025
-0.013
-0.013
A hsa-miR-2116-5p
hsa-miR-22-5p
hsa-miR-4273
hsa-miR-4677-5p
hsa-miR-578
hsa-miR-6739-3p
hsa-miR-7156-5p
3
3
3
3
3
3
3
 acAAGAACAatag
acAAGAACAatag
acaAGAACAAtag
acAAGAACAAtag
ACAAGAAcaatag
acaAGAACAAtag
acaAGAACAAtag
 Created
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
N
 0.025
0.024
0.03
0.044
0.02
-0.009
0.037
8088771 rs148412769 G
A hsa-miR-4803
15
 ttaaTTATGTTgt
 Created
N
 -0.109

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