SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_000157 |
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Gene Symbol: | GBA |
Description: | Homo sapiens glucosidase, beta, acid (GBA), transcript variant 1, mRNA. |
Gene Location: | chr1(-):155204238-155211069 |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr1:g.155234903G>A | COSN5265403 | SNUH_G25_S1 | [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-146b-3p |
gagggcacaACAGGGCcag |
0 | UGCCCUGU | m7b | (m6b->m7b) | no TS | -0.219000 | No effect |
hsa-miR-3173-5p |
gagggcacaGCAGGGCcag |
4 |
UGCCCUGC | m7b | (m7b->m6b) | -0.257000 | no TS |
0.690000 |
hsa-miR-370 |
gagggcaCAGCAGGgccag |
4 |
GCCUGCUG | m7b | Disrupted | -0.136000 | no TS |
0.860000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
155234903 | rs144123706 | G | G |
hsa-miR-3173-5p hsa-miR-370-3p hsa-miR-6799-3p hsa-miR-6889-3p hsa-miR-6893-3p |
4 4 4 2 4 |
ggcacaGCAGGGC ggcaCAGCAGGgc ggcacaGCAGGGC GGCACAGcagggc ggcaCAGCAGGgc |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
-0.257 -0.136 -0.257 -0.191 -0.154 |
A |
hsa-miR-146b-3p hsa-miR-550b-2-5p |
4 2 |
ggcacaACAGGGC GGCACAAcagggc |
Created Created |
N N |
-0.219 -0.166 |