SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_021903
Gene Symbol: GABBR1
Description: Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 1, mRNA.
Gene Location: chr6(-):29570004-29596005
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr6:g.29602941C>T COSN9779887 AOCS-086-3-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3150b-3p tgcatccTCTCCTCtcctg
 0 UGAGGAGA m7b Created -0.074000 -0.097000 -0.030000
hsa-miR-4784 tgcatccTCTCCTCtcctg
 0 UGAGGAGA m7b Created -0.071000 -0.103000 -0.710000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.29603266C>T COSN2382689 TCGA-A5-A0VQ-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-103a-3p ctgctcacATGCTGCctcc
 0 AGCAGCAU m7b Created no TS -0.119000 -6.290000
hsa-miR-107 ctgctcacATGCTGCctcc
 0 AGCAGCAU m7b Created no TS -0.119000 -7.490000
hsa-miR-3607-5p ctgcTCACATGCtgcctcc
 5
 GCAUGUGA m8a Created -0.123000 -0.187000 -0.020000
hsa-miR-885-3p ctgctcacaCGCTGCCTcc
 2
 AGGCAGCG m8a (m8a->m7a) -0.239000 no TS 0.710000
hsa-miR-103a-3p ctgctcacATGCTGCctcc
 0 AGCAGCAU m7b Created no TS -0.119 -6.29
hsa-miR-107 ctgctcacATGCTGCctcc
 0 AGCAGCAU m7b Created no TS -0.119 -7.49
hsa-miR-3607-5p ctgcTCACATGCtgcctcc
 0 GCAUGUGA m8a Created -0.123 -0.187 -0.02
hsa-miR-885-3p ctgctcacaCGCTGCCTcc
 0 AGGCAGCG m8a (m8a->m7a) -0.239 no TS 0.71

Mutation Mutation ID Sample Name Cancer Type
chr6:g.29603351T>A COSN9779888 AOCS-112-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-539-5p aacagacctATTTCTCtct
 2
 GGAGAAAU m7b (m6b->m7b) 0.003000 -0.073000 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.29603517G>T COSN1083970 TCGA-D1-A103-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-193a-3p gacaGGCCAGTagggggag
 2
 AACUGGCC m7b Disrupted -0.433000 no TS 1.900000
hsa-miR-193b-3p gacaGGCCAGTagggggag
 2
 AACUGGCC m7b Disrupted -0.433000 no TS 11.990000
hsa-miR-3176 gacAGGCCAGTagggggag
 5
 ACUGGCCU m8a Disrupted -0.162000 no TS 0.300000
hsa-miR-3922-3p gacAGGCCAGtagggggag
 5
 UCUGGCCU m7b (m7b->m6c) -0.153000 no TS 6.200000
hsa-miR-5197-5p gacagGCCATTagggggag
 0 CAAUGGCA m6b Created no TS -0.069000 -14.490000
hsa-miR-892b gacagGCCAGTagggggag
 3
 CACUGGCU m6b Disrupted -0.122000 no TS 12.310000
hsa-miR-193a-3p gacaGGCCAGTagggggag
 0 AACUGGCC m7b Disrupted -0.433 no TS 1.9
hsa-miR-193b-3p gacaGGCCAGTagggggag
 0 AACUGGCC m7b Disrupted -0.433 no TS 11.99
hsa-miR-3176 gacAGGCCAGTagggggag
 0 ACUGGCCU m8a Disrupted -0.162 no TS 0.3
hsa-miR-3922-3p gacAGGCCAGtagggggag
 0 UCUGGCCU m7b (m7b->m6c) -0.153 no TS 6.2
hsa-miR-5197-5p gacagGCCATTagggggag
 0 CAAUGGCA m6b Created no TS -0.069 -14.49
hsa-miR-892b gacagGCCAGTagggggag
 0 CACUGGCU m6b Disrupted -0.122 no TS 12.31

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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