SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_152871
Gene Symbol: FAS
Description: Homo sapiens Fas (TNF receptor superfamily, member 6) (FAS), transcript variant 1, mRNA.
Gene Location: chr10(+):90750287-90775542
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.89014550A>G COSN5888337 RK190_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3163 actgggtacATTTTATcat
 0 UAUAAAAU m7b (m7b->m6c) -0.009000 no TS 0.020000
hsa-miR-3662 actgggtaCATTTTatcat
 5
 GAAAAUGA m6b Disrupted 0.118000 0.094000 0.290000
hsa-miR-424-3p actgggtACGTTTTatcat
 0 CAAAACGU m7b Created no TS -0.268000 -0.100000
hsa-miR-548ad actgggtaCGTTTTatcat
 0 GAAAACGA m6b Created no TS -0.089000 1.000000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.89014996A>G COSN1124101 HX17T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-302a-5p agaaTTTAAGTaaggctct
 2
 ACUUAAAC m7a Created -0.041000 -0.041000 No effect
hsa-miR-302a-5p agaaTTTAAGTaaggctct
 0 ACUUAAAC m7a Created -0.041 -0.041 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.89015535C>A COSN7074141 8013946 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1275 tcataCCCCCAagtttcta
 1
 GUGGGGGA m6b Disrupted -0.573000 -0.377000 0.010000
hsa-miR-3170 tcatACCCCAaagtttcta
 2
 CUGGGGUU m6b Created -0.173000 -0.371000 No effect
hsa-miR-4665-5p tcataCCCCCAagtttcta
 1
 CUGGGGGA m6b Disrupted -0.611000 -0.398000 No effect
hsa-miR-5572 tcatACCCCAAagtttcta
 3
 GUUGGGGU m7b Created -0.115000 -0.492000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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