SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_144963
Gene Symbol: FAM91A1
Description: Homo sapiens family with sequence similarity 91, member A1 (FAM91A1), mRNA.
Gene Location: chr8(+):124780881-124827690
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr8:g.123812735C>T 13_160 SJMB024_D Medulloblastoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548t-5p tcaCACTTTTtgccttttt
0 CAAAAGUG m7b (m6b->m7b) 0.115 0.031 -0.05

Mutation Mutation ID Sample Name Cancer Type
chr8:g.123812737G>A COSN9254708 C0009T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3714 acactttCTGCCTTttttc
12
GAAGGCAG m7b Disrupted -0.280000 no TS 1.410000
hsa-miR-3927 acacttTCTACCTtttttc
0 CAGGUAGA m7b Created no TS -0.304000 -0.340000
hsa-miR-4650-3p acactTTCTACCTtttttc
0 AGGUAGAA m8a Created no TS -0.247000 -0.050000
hsa-miR-548an acactttcTGCCTTTTttc
15
AAAAGGCA m8a Disrupted -0.232000 -0.047000 1.440000
hsa-miR-548m acactttcTACCTTTtttc
0 CAAAGGUA m7b Created no TS -0.166000 -0.160000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.123812987C>T COSN14944851 LP6005409-DNA_G03 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-132-3p ttatgatGACTGTTAtgtt
16
UAACAGUC m8a Disrupted -0.352000 no TS 0.050000
hsa-miR-212-3p ttatgatGACTGTTAtgtt
16
UAACAGUC m8a Disrupted -0.341000 no TS 1.130000


Mutation Mutation ID Sample Name Cancer Type
chr8:g.123813222G>A COSN9254709 C0089T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr8:g.123813661T>A COSN14874425 LP2000108-DNA_A01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-130a-5p tcttaaattAATGTGAAta
7
UUCACAUU m8a (m7b->m8a) -0.159000 -0.240000 -1.480000
hsa-miR-23a-3p tcttaaattAATGTGAata
7
AUCACAUU m7b (m6c->m7b) -0.109000 -0.198000 -1.520000
hsa-miR-23b-3p tcttaaattAATGTGAata
7
AUCACAUU m7b (m6c->m7b) -0.109000 -0.198000 -1.520000
hsa-miR-23c tcttaaattAATGTGAata
7
AUCACAUU m7b (m6c->m7b) -0.109000 -0.198000 -1.520000
hsa-miR-323a-3p tcttaaatTAATGTGaata
5
CACAUUAC m7a Created 0.005000 0.005000 -0.050000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.123813768A>C COSN8063617 8069453 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-145-3p aataattGGAATCactttt
11
GGAUUCCU m6b Disrupted -0.062000 no TS 0.010000
hsa-miR-192-3p aataATTGGCAtcactttt
0 CUGCCAAU m7b Created no TS -0.125000 -0.290000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.123814240G>C COSN8063618 8036161 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-134 tacgactctCAGTCACtca
16
UGUGACUG m7b (m6c->m7b) -0.233000 -0.331000 -0.610000
hsa-miR-3118 tacgactctCAGTCACtca
16
UGUGACUG m7b (m6c->m7b) -0.252000 -0.350000 -0.040000
hsa-miR-3136-5p tacgactcTCAGTCActca
0 CUGACUGA m7b Created no TS -0.056000 -0.840000
hsa-miR-4439 tacgactcTCAGTCACtca
0 GUGACUGA m8a Created no TS -0.028000 -2.940000
hsa-miR-4513 tacgactcTCAGTCactca
0 AGACUGAC m6b Created no TS -0.041000 -0.010000
hsa-miR-759 tacgACTCTGagtcactca
2
GCAGAGUG m6b Disrupted -0.021000 no TS 3.550000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.123814451A>T COSN2259175 RK159_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4666a-5p tgtaatgACATGTAcacta
0 AUACAUGU m7b Disrupted -0.078000 -0.054000 0.390000
hsa-miR-493-5p tgtaatgacATGTACActa
9
UUGUACAU m7b (m7b->m6c) 0.003000 no TS 0.130000

Mutation Mutation ID Sample Name Cancer Type
chr8:g.123814800A>C COSN8063619 8034061 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4678 tacttATACCTTaactcat
0 AAGGUAUU m7a Created NA NA -0.030000
hsa-miR-548ag tacttaTACCTTaactcat
11
AAAGGUAA m6b Created -0.109000 -0.167000 -0.020000
hsa-miR-548ai tacttaTACCTTaactcat
11
AAAGGUAA m6b Created -0.156000 -0.220000 No effect
hsa-miR-568 tacTTATACATtaactcat
9
AUGUAUAA m8a Disrupted -0.350000 -0.286000 0.050000
hsa-miR-569 tacttataCATTAACTcat
2
AGUUAAUG m8a Disrupted -0.104000 no TS No effect
hsa-miR-570-5p tacttaTACCTTaactcat
11
AAAGGUAA m6b Created -0.156000 -0.220000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr8:g.123815334G>A COSN8063620 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3662 cagtggaTCATTTTCtgtt
5
GAAAAUGA m8a Created 0.135000 0.106000 No effect
hsa-miR-548ad cagtggaTCGTTTTCtgtt
2
GAAAACGA m8a Disrupted -0.177000 no TS 0.260000
hsa-miR-640 cagTGGATCATtttctgtt
5
AUGAUCCA m8a Created -0.218000 -0.443000 -0.030000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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