SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_139076
Gene Symbol: FAM175A
Description: Homo sapiens family with sequence similarity 175, member A (FAM175A), mRNA.
Gene Location: chr4(-):84382093-84406290
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr4:g.83461012T>T ICGC_66077 TCGA-GV-A3QI-01A-11D-A21Z-08 BladderUrothelialCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr4:g.83461190C>T ICGC_1325366 TCGA-D1-A17B-01A-22D-A12J-09 UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-144-5p atttattccTGATATCtga
 0 GGAUAUCA m7b (m6b->m7b) -0.069 -0.23 -1.45
hsa-miR-3074-3p atttattcCTGATATCtga
 0 GAUAUCAG m8a Created no TS -0.119 -3.94
hsa-miR-425-3p atttaTTCCCGATatctga
 0 AUCGGGAA m8a Disrupted -0.346 no TS 0.67
hsa-miR-873-5p atttaTTCCTGatatctga
 0 GCAGGAAC m6b Created no TS -0.122 No effect

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83461263A>G COSN5156682 PD3904a [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-345-5p gttggtttGAGTCAGtatt
 1
 GCUGACUC m7b Disrupted -0.260000 no TS No effect
hsa-miR-371a-5p gttgGTTTGAGTcagtatt
 0 ACUCAAAC m8a Disrupted -0.048000 0.023000 No effect
hsa-miR-888-5p gttggTTTGAGTcagtatt
 0 UACUCAAA m7b Disrupted -0.040000 no TS 0.020000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83462190C>G COSN1302052 BN15T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1254 aaagtgagaCCAGGCacag
 2
 AGCCUGGA m6b Disrupted -0.319000 -0.179000 4.610000
hsa-miR-3663-5p aaagtgAGACCAGgcacag
 2
 GCUGGUCU m7b Disrupted -0.188000 -0.093000 -1.800000
hsa-miR-370 aaagtgagAGCAGGCacag
 0 GCCUGCUG m7a Created NA NA -4.970000
hsa-miR-4763-5p aaagtgagaGCAGGCacag
 0 CGCCUGCC m6b Created no TS -0.168000 -3.630000
hsa-miR-1254 aaagtgagaCCAGGCacag
 2
 AGCCUGGA m6b Disrupted -0.319000 -0.179000 4.610000
hsa-miR-3663-5p aaagtgAGACCAGgcacag
 2
 GCUGGUCU m7b Disrupted -0.188000 -0.093000 -1.800000
hsa-miR-370 aaagtgagAGCAGGCacag
 0 GCCUGCUG m7a Created NA NA -4.970000
hsa-miR-4763-5p aaagtgagaGCAGGCacag
 0 CGCCUGCC m6b Created no TS -0.168000 -3.630000
hsa-miR-1254 aaagtgagaCCAGGCacag
 0 AGCCUGGA m6b Disrupted -0.319 -0.179 4.61
hsa-miR-3663-5p aaagtgAGACCAGgcacag
 0 GCUGGUCU m7b Disrupted -0.188 -0.093 -1.8
hsa-miR-370 aaagtgagAGCAGGCacag
 0 GCCUGCUG m7a Created NA NA -4.97
hsa-miR-4763-5p aaagtgagaGCAGGCacag
 0 CGCCUGCC m6b Created no TS -0.168 -3.63

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83462384T>C COSN1302054 HCC133T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1205 ttgagctaCCTGCAGtaag
 0 UCUGCAGG m7b Created no TS -0.311000 -0.060000
hsa-miR-17-3p ttgagctacCTGCAGTaag
 0 ACUGCAGU m7a (m6a->m7a) NA NA -3.680000
hsa-miR-2276 ttgagctaCTTGCAGtaag
 0 UCUGCAAG m7b Disrupted -0.260000 no TS 1.670000
hsa-miR-3665 ttgagctACCTGCagtaag
 0 AGCAGGUG m6b Created no TS -0.160000 -3.820000
hsa-miR-4418 ttgagctacCTGCAGTaag
 4
 CACUGCAG m7b (m6b->m7b) -0.296000 -0.549000 -2.980000
hsa-miR-509-3-5p ttgagctacCTGCAGTAag
 4
 UACUGCAG m8a (m7a->m8a) -0.289000 -0.536000 -0.080000
hsa-miR-509-5p ttgagctacCTGCAGTAag
 4
 UACUGCAG m8a (m7a->m8a) -0.289000 -0.528000 No effect
hsa-miR-562 ttgaGCTACTTgcagtaag
 1
 AAAGUAGC m7b Disrupted -0.224000 no TS 0.290000
hsa-miR-5697 ttgagCTACTTGcagtaag
 1
 UCAAGUAG m7b Disrupted -0.168000 no TS 4.180000
hsa-miR-657 ttgagctACCTGCagtaag
 0 GGCAGGUU m6b Created no TS -0.184000 -5.380000
hsa-miR-1205 ttgagctaCCTGCAGtaag
 0 UCUGCAGG m7b Created no TS -0.311000 -0.060000
hsa-miR-17-3p ttgagctacCTGCAGTaag
 0 ACUGCAGU m7a (m6a->m7a) NA NA -3.680000
hsa-miR-2276 ttgagctaCTTGCAGtaag
 0 UCUGCAAG m7b Disrupted -0.260000 no TS 1.670000
hsa-miR-3665 ttgagctACCTGCagtaag
 0 AGCAGGUG m6b Created no TS -0.160000 -3.820000
hsa-miR-4418 ttgagctacCTGCAGTaag
 4
 CACUGCAG m7b (m6b->m7b) -0.296000 -0.549000 -2.980000
hsa-miR-509-3-5p ttgagctacCTGCAGTAag
 4
 UACUGCAG m8a (m7a->m8a) -0.289000 -0.536000 -0.080000
hsa-miR-509-5p ttgagctacCTGCAGTAag
 4
 UACUGCAG m8a (m7a->m8a) -0.289000 -0.528000 No effect
hsa-miR-562 ttgaGCTACTTgcagtaag
 1
 AAAGUAGC m7b Disrupted -0.224000 no TS 0.290000
hsa-miR-5697 ttgagCTACTTGcagtaag
 1
 UCAAGUAG m7b Disrupted -0.168000 no TS 4.180000
hsa-miR-657 ttgagctACCTGCagtaag
 0 GGCAGGUU m6b Created no TS -0.184000 -5.380000
hsa-miR-1205 ttgagctaCCTGCAGtaag
 0 UCUGCAGG m7b Created no TS -0.311 -0.06
hsa-miR-17-3p ttgagctacCTGCAGTaag
 0 ACUGCAGU m7a (m6a->m7a) NA NA -3.68
hsa-miR-2276 ttgagctaCTTGCAGtaag
 0 UCUGCAAG m7b Disrupted -0.26 no TS 1.67
hsa-miR-3665 ttgagctACCTGCagtaag
 0 AGCAGGUG m6b Created no TS -0.16 -3.82
hsa-miR-4418 ttgagctacCTGCAGTaag
 0 CACUGCAG m7b (m6b->m7b) -0.296 -0.549 -2.98
hsa-miR-509-3-5p ttgagctacCTGCAGTAag
 0 UACUGCAG m8a (m7a->m8a) -0.289 -0.536 -0.08
hsa-miR-509-5p ttgagctacCTGCAGTAag
 0 UACUGCAG m8a (m7a->m8a) -0.289 -0.528 No effect
hsa-miR-562 ttgaGCTACTTgcagtaag
 0 AAAGUAGC m7b Disrupted -0.224 no TS 0.29
hsa-miR-5697 ttgagCTACTTGcagtaag
 0 UCAAGUAG m7b Disrupted -0.168 no TS 4.18
hsa-miR-657 ttgagctACCTGCagtaag
 0 GGCAGGUU m6b Created no TS -0.184 -5.38

Mutation Mutation ID Sample Name Cancer Type
chr4:g.83462400T>C COSN1302056 HCC133T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3606 tattgttTTCACTAtgttg
 0 UUAGUGAA m7b Created -0.233000 -0.435000 -2.240000
hsa-miR-548ac tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.019000 0.007000 6.740000
hsa-miR-548ae tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.031000 0.010000 0.476000
hsa-miR-548ah-3p tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.028000 0.010000 0.310000
hsa-miR-548am-3p tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.028000 0.010000 0.380000
hsa-miR-548aq-3p tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.028000 0.010000 0.480000
hsa-miR-548d-3p tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.036000 0.021000 2.930000
hsa-miR-548h-3p tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.022000 0.007000 2.070000
hsa-miR-548z tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.022000 0.007000 2.070000
hsa-miR-570-3p tatTGTTTTCactatgttg
 0 CGAAAACA m7b (m6c->m7b) no TS -0.211000 -3.200000
hsa-miR-3606 tattgttTTCACTAtgttg
 0 UUAGUGAA m7b Created -0.233000 -0.435000 -2.240000
hsa-miR-548ac tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.019000 0.007000 6.740000
hsa-miR-548ae tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.031000 0.010000 0.476000
hsa-miR-548ah-3p tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.028000 0.010000 0.310000
hsa-miR-548am-3p tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.028000 0.010000 0.380000
hsa-miR-548aq-3p tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.028000 0.010000 0.480000
hsa-miR-548d-3p tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.036000 0.021000 2.930000
hsa-miR-548h-3p tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.022000 0.007000 2.070000
hsa-miR-548z tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.022000 0.007000 2.070000
hsa-miR-570-3p tatTGTTTTCactatgttg
 0 CGAAAACA m7b (m6c->m7b) no TS -0.211000 -3.200000
hsa-miR-3606 tattgttTTCACTAtgttg
 0 UUAGUGAA m7b Created -0.233000 -0.435000 -2.240000
hsa-miR-548ac tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.019000 0.007000 6.740000
hsa-miR-548ae tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.031000 0.010000 0.476000
hsa-miR-548ah-3p tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.028000 0.010000 0.310000
hsa-miR-548am-3p tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.028000 0.010000 0.380000
hsa-miR-548aq-3p tattGTTTTTactatgttg
 6
 CAAAAACU m6b Disrupted 0.028000 0.010000 0.480000
hsa-miR-548d-3p tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.036000 0.021000 2.930000
hsa-miR-548h-3p tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.022000 0.007000 2.070000
hsa-miR-548z tattGTTTTTactatgttg
 6
 CAAAAACC m6b Disrupted 0.022000 0.007000 2.070000
hsa-miR-570-3p tatTGTTTTCactatgttg
 0 CGAAAACA m7b (m6c->m7b) no TS -0.211000 -3.200000
hsa-miR-3606 tattgttTTCACTAtgttg
 0 UUAGUGAA m7b Created -0.233 -0.435 -2.24
hsa-miR-548ac tattGTTTTTactatgttg
 0 CAAAAACC m6b Disrupted 0.019 0.007 6.74
hsa-miR-548ae tattGTTTTTactatgttg
 0 CAAAAACU m6b Disrupted 0.031 0.01 0.476
hsa-miR-548ah-3p tattGTTTTTactatgttg
 0 CAAAAACU m6b Disrupted 0.028 0.01 0.31
hsa-miR-548am-3p tattGTTTTTactatgttg
 0 CAAAAACU m6b Disrupted 0.028 0.01 0.38
hsa-miR-548aq-3p tattGTTTTTactatgttg
 0 CAAAAACU m6b Disrupted 0.028 0.01 0.48
hsa-miR-548d-3p tattGTTTTTactatgttg
 0 CAAAAACC m6b Disrupted 0.036 0.021 2.93
hsa-miR-548h-3p tattGTTTTTactatgttg
 0 CAAAAACC m6b Disrupted 0.022 0.007 2.07
hsa-miR-548z tattGTTTTTactatgttg
 0 CAAAAACC m6b Disrupted 0.022 0.007 2.07
hsa-miR-570-3p tatTGTTTTCactatgttg
 0 CGAAAACA m7b (m6c->m7b) no TS -0.211 -3.2

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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