SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_000131 |
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Gene Symbol: | F7 |
Description: | Homo sapiens coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant 1, mRNA. |
Gene Location: | chr13(+):113760104-113774995 |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr13:g.113119018C>A | COSN8587181 | J30_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1825 |
cccagcaGCACTGGcctgt |
0 | UCCAGUGC | m7b | Created | no TS | 0.000000 | No effect | |
hsa-miR-4446-3p |
cccagCAGCCCTGgcctgt |
2 |
CAGGGCUG | m8a | Disrupted | -0.356000 | -0.178000 | No effect | |
hsa-miR-4685-5p |
cccagcaGCCCTGGcctgt |
1 |
CCCAGGGC | m7b | Disrupted | -0.292000 | -0.146000 | No effect | |
hsa-miR-512-3p |
cccagCAGCACTggcctgt |
0 | AAGUGCUG | m7b | Created | no TS | 0.000000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr13:g.113120488G>A | COSN6538556 | ICGC_MB78 | [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1291 |
tgCAGGGCCAtcctgggca |
0 | UGGCCCUG | m8a | (m7a->m8a) | -0.162000 | -0.380000 |
0.010000 |
hsa-miR-2392 |
tgcagggCCATCCTgggca |
0 | UAGGAUGG | m7b | Created | no TS | -0.050000 | No effect |
hsa-miR-328 |
tgcAGGGCCAtcctgggca |
0 | CUGGCCCU | m7b | (m6b->m7b) | no TS | -0.135000 | No effect |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
113120483 | rs3093258 | G | G |
hsa-miR-1205 hsa-miR-1291 hsa-miR-3173-5p hsa-miR-6775-3p hsa-miR-6799-3p |
0 |
CCTGCAGggccgt cctgCAGGGCCgt cctGCAGGGCcgt cctgCAGGGCCgt cctGCAGGGCcgt |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
-0.081 -0.162 -0.166 -0.162 -0.184 |
A |
hsa-miR-6511b-5p hsa-miR-6811-5p hsa-miR-6841-3p |
0 |
CCTGCAAggccgt CCTGCAAggccgt ccTGCAAGGccgt |
Created Created Created |
N N N |
-0.104 -0.101 -0.105 |