SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_004452
Gene Symbol: ESRRB
Description: Homo sapiens estrogen-related receptor beta (ESRRB), mRNA.
Gene Location: chr14(+):76837689-76968180
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr14:g.76501367C>T COSN7026793 8012341 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3185 gggaaCTTCTTCgggccac
0 AGAAGAAG m7b Created no TS -0.033000 -0.100000
hsa-miR-4671-5p gggaactTCTTCGGgccac
0 ACCGAAGA m7b Created no TS -0.201000 -6.170000

Mutation Mutation ID Sample Name Cancer Type
chr14:g.76501420C>T COSN5209745 SS6003125 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-150-5p cagcagagTTGGGAGgcca
0 UCUCCCAA m7b Created no TS -0.030000 -6.280000
hsa-miR-4431 cagcAGAGTCGggaggcca
0 GCGACUCU m7b Disrupted -0.123000 no TS No effect
hsa-miR-4522 cagCAGAGTCgggaggcca
4
UGACUCUG m7b (m7b->m6b) -0.160000 -0.111000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr14:g.76501606A>G COSN1659595 RK067_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-103a-2-5p caccaaagAGAAGCactat
0 AGCUUCUU m6b Created no TS -0.125000 -3.200000
hsa-miR-130b-5p caccAAAGAGaagcactat
0 ACUCUUUC m6b Created no TS -0.018000 2.590000
hsa-miR-3140-3p caccaaagAAAAGCactat
10
AGCUUUUG m6b Disrupted -0.030000 no TS 0.240000
hsa-miR-4753-3p caccAAAGAGAAgcactat
0 UUCUCUUU m8a Created no TS -0.081000 -0.100000
hsa-miR-942 caccaaAGAGAAGcactat
0 UCUUCUCU m7b Created no TS -0.147000 -0.140000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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