SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001040275
Gene Symbol: ESR2
Description: Homo sapiens estrogen receptor 2 (ER beta) (ESR2), transcript variant b, mRNA.
Gene Location: chr14(-):64693750-64761128
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr14:g.64227168G>A COSN1169977 HCC121T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr14:g.64227324C>T COSN7024101 8067232 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3123 agacggATTCTCTtcagat
 4
 CAGAGAAU m7b Disrupted -0.027000 no TS 3.090000
hsa-miR-3185 agacggattTTCTTCagat
 0 AGAAGAAG m6b Created no TS -0.028000 -4.520000
hsa-miR-4668-3p agacGGATTTTCttcagat
 0 GAAAAUCC m8a Created no TS -0.044000 -5.600000
hsa-miR-4709-3p agacggattCTCTTCAgat
 3
 UUGAAGAG m7b (m7b->m6b) -0.142000 no TS 2.620000

Mutation Mutation ID Sample Name Cancer Type
chr14:g.64227477G>T COSN8864863 SNUH_G16_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3616-5p ttCACTTCATtttccctct
 2
 AUGAAGUG m8a (m7b->m8a) -0.231000 -0.258000 -0.410000
hsa-miR-3646 ttcacTTCATTTTccctct
 0 AAAAUGAA m8a Created no TS 0.003000 -3.550000
hsa-miR-3662 ttcactTCATTTTCcctct
 0 GAAAAUGA m8a Created no TS -0.023000 1.430000
hsa-miR-4668-5p ttcacttcaTTTTCCCTct
 0 AGGGAAAA m8a (m7a->m8a) no TS -0.174000 -0.770000
hsa-miR-4738-3p ttcacttCAGTTTCcctct
 1
 UGAAACUG m7b Disrupted -0.140000 no TS 7.820000
hsa-miR-573 ttCACTTCAGtttccctct
 2
 CUGAAGUG m8a (m8a->m7b) -0.222000 -0.249000 -0.370000

Mutation Mutation ID Sample Name Cancer Type
chr14:g.64227477G>A COSN8864864 SNUH_G45_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4738-3p ttcacttCAGTTTCcctct
 1
 UGAAACUG m7b Disrupted -0.140000 no TS 7.820000
hsa-miR-573 ttCACTTCAGtttccctct
 2
 CUGAAGUG m8a (m8a->m7b) -0.222000 -0.392000 -0.070000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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