SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001042599
Gene Symbol: ERBB4
Description: Homo sapiens v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4), transcript variant JM-a/CVT-2, mRNA.
Gene Location: chr2(-):212240441-213403352
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.211375857C>T COSN9873031 C0072T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-130a-5p tatagAATGTGAActgctt
 9
 UUCACAUU m8a Created -0.012000 -0.198000 No effect
hsa-miR-23a-3p tatagAATGTGAactgctt
 9
 AUCACAUU m7b Created -0.055000 -0.241000 No effect
hsa-miR-23b-3p tatagAATGTGAactgctt
 9
 AUCACAUU m7b Created -0.044000 -0.230000 No effect
hsa-miR-23c tatagAATGTGAactgctt
 9
 AUCACAUU m7b Created 0.003000 -0.183000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211375975G>A COSN15312626 LP6007404-DNA_A01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-302a-5p ttgttaTTTAAGaatgagg
 1
 ACUUAAAC m6b Created 0.388000 0.403000 No effect
hsa-miR-3671 ttgtTATTTGAgaatgagg
 21
 AUCAAAUA m7b Disrupted -0.044000 -0.002000 No effect
hsa-miR-371a-5p ttgttaTTTGAGaatgagg
 7
 ACUCAAAC m6b Disrupted 0.127000 0.162000 No effect
hsa-miR-371b-5p ttgttaTTTGAGaatgagg
 7
 ACUCAAAA m6b Disrupted 0.115000 0.142000 No effect
hsa-miR-373-5p ttgttaTTTGAGaatgagg
 7
 ACUCAAAA m6b Disrupted 0.121000 0.145000 No effect
hsa-miR-5692a ttgTTATTTGagaatgagg
 1
 CAAAUAAU m7a (m7a->m6b) 0.694000 0.767000 No effect
hsa-miR-616-5p ttgttaTTTGAGaatgagg
 7
 ACUCAAAA m6b Disrupted 0.108000 0.142000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211376051A>G COSN8278694 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4704-5p attttTAGTGTactttctc
 0 GACACUAG m6b Created no TS -0.120000 -1.270000
hsa-miR-548av-5p atttttagtGTACTTTctc
 4
 AAAAGUAC m7b (m6b->m7b) 0.145000 0.024000 -0.010000
hsa-miR-548k atttttagtGTACTTTctc
 4
 AAAAGUAC m7b (m6b->m7b) 0.145000 0.024000 -0.010000
hsa-miR-548l atttttagtATACTTTctc
 4
 AAAAGUAU m7b (m7b->m6b) 0.261000 0.321000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211376095A>T COSN8608544 202_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1258 ggatcatgcTCCTAACaca
 2
 AGUUAGGA m7b (m6b->m7b) -0.112000 -0.281000 No effect
hsa-miR-28-5p ggatcatGCTCCTaacaca
 0 AAGGAGCU m6b Created -0.016000 -0.189000 -0.010000
hsa-miR-3139 ggatcatGCTCCTAacaca
 0 UAGGAGCU m7a Created 0.031000 -0.142000 No effect
hsa-miR-4266 ggatcatgCTCCTAacaca
 0 CUAGGAGG m6b Created -0.064000 -0.193000 No effect
hsa-miR-708-5p ggatcatGCTCCTaacaca
 0 AAGGAGCU m6b Created 0.012000 -0.168000 -0.260000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211376177C>T COSN6935917 8035823 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-519a-3p ctcTGCACTTgcttacaca
 18
 AAAGUGCA m7b (m6c->m7b) -0.148000 -0.228000 -0.010000
hsa-miR-519b-3p ctcTGCACTTgcttacaca
 18
 AAAGUGCA m7b (m6c->m7b) -0.148000 -0.228000 -1.110000
hsa-miR-519c-3p ctcTGCACTTgcttacaca
 18
 AAAGUGCA m7b (m6c->m7b) -0.148000 -0.228000 -0.470000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211376421T>A COSN8608545 1428_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-335-3p actgtatgtATGAAAAtgt
 7
 UUUUUCAU m7b (m6b->m7b) 0.949000 0.964000 No effect
hsa-miR-485-3p actgtaTGTATGAaaatgt
 1
 GUCAUACA m7b Created 0.069000 -0.108000 No effect
hsa-miR-539-3p actgtaTGTATGAaaatgt
 1
 AUCAUACA m7b Created 0.042000 -0.188000 -0.010000
hsa-miR-607 actgtatgTTTGAAaatgt
 5
 GUUCAAAU m6b Disrupted 0.273000 0.234000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211376975T>G COSN8608546 J52_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-100-5p agcataaACGGGTactgct
 0 AACCCGUA m6b Created no TS -0.166000 -5.830000
hsa-miR-624-5p agcataaacTGGTACTgct
 16
 UAGUACCA m7b (m7b->m6b) -0.042000 no TS 1.210000
hsa-miR-99a-5p agcataaACGGGTactgct
 0 AACCCGUA m6b Created no TS -0.169000 -3.120000
hsa-miR-99b-5p agcataaACGGGTactgct
 0 CACCCGUA m6b Created no TS -0.169000 -11.100000


Mutation Mutation ID Sample Name Cancer Type
chr2:g.211377002A>C COSN8765487 SS6003115 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.211377052T>A COSN9873032 C0056T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4703-3p gtaatCAACTACgaaagtt
 3
 UGUAGUUG m7b Disrupted -0.060000 no TS 0.040000
hsa-miR-653 gtaaTCAACAacgaaagtt
 0 GUGUUGAA m6b Created -0.265000 -0.227000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211377211T>C COSN5496096 RK088_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5093 caaatgtCATTTCCagatt
 13
 AGGAAAUG m7b Disrupted 0.055000 no TS No effect
hsa-miR-875-3p caaatgtcaTTTCCAGatt
 13
 CCUGGAAA m7b (m7b->m6b) 0.145000 0.141000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211377232G>A COSN8608547 4095_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-10b-3p tattgacacGAATCTGgtt
 2
 ACAGAUUC m7b (m7b->m6b) -0.131000 -0.175000 0.260000
hsa-miR-187-3p tattGACACGAatctggtt
 1
 UCGUGUCU m7a Disrupted -0.099000 no TS 2.730000
hsa-miR-5010-3p tattgACACAAAtctggtt
 2
 UUUUGUGU m7b Created 0.199000 0.285000 No effect
hsa-miR-592 tatTGACACAAatctggtt
 2
 UUGUGUCA m8a Created 0.021000 -0.049000 -0.940000
hsa-miR-597 tatTGACACAaatctggtt
 2
 UGUGUCAC m7a (m6b->m7a) 0.033000 0.015000 No effect
hsa-miR-599 tattGACACAAatctggtt
 2
 GUUGUGUC m7b Created 0.094000 0.057000 -0.040000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211377355A>G COSN1822240 RK022_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3152-5p ctgtAGGCAATagtctaac
 7
 AUUGCCUC m7a Disrupted -0.012000 -0.012000 No effect
hsa-miR-4774-3p ctgTAGGCAATagtctaac
 11
 AUUGCCUA m8a Disrupted -0.054000 -0.067000 No effect
hsa-miR-3152-5p ctgtAGGCAATagtctaac
 0 AUUGCCUC m7a Disrupted -0.012 -0.012 No effect
hsa-miR-4774-3p ctgTAGGCAATagtctaac
 0 AUUGCCUA m8a Disrupted -0.054 -0.067 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211377395T>A COSN1822241 RK022_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-129-5p ttgtGCAAAAAtacaaata
 0 CUUUUUGC m7b Created 0.409000 0.506000 No effect
hsa-miR-3680-3p ttgTGCAAAAatacaaata
 7
 UUUUGCAU m7a (m6b->m7a) 0.020000 0.073000 No effect
hsa-miR-450b-5p ttgTGCAAAAatacaaata
 7
 UUUUGCAA m7a (m6b->m7a) -0.058000 -0.018000 No effect
hsa-miR-507 ttGTGCAAAAatacaaata
 3
 UUUUGCAC m8a (m7b->m8a) -0.099000 -0.069000 No effect
hsa-miR-568 ttgtgcaaaTATACAaata
 10
 AUGUAUAA m6b Disrupted 0.143000 0.075000 No effect
hsa-miR-129-5p ttgtGCAAAAAtacaaata
 0 CUUUUUGC m7b Created 0.409 0.506 No effect
hsa-miR-3680-3p ttgTGCAAAAatacaaata
 0 UUUUGCAU m7a (m6b->m7a) 0.02 0.073 No effect
hsa-miR-450b-5p ttgTGCAAAAatacaaata
 0 UUUUGCAA m7a (m6b->m7a) -0.058 -0.018 No effect
hsa-miR-507 ttGTGCAAAAatacaaata
 0 UUUUGCAC m8a (m7b->m8a) -0.099 -0.069 No effect
hsa-miR-568 ttgtgcaaaTATACAaata
 0 AUGUAUAA m6b Disrupted 0.143 0.075 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211377400G>A 4_2056 UNP804168 Acute myeloid leukemia
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7a-2-3p tatattTGTACAaatatac
 7
 CUGUACAG m6b Created -0.3 -0.276 No effect
hsa-let-7g-3p tatattTGTACAaatatac
 7
 CUGUACAG m6b Created -0.269 -0.245 -0.06
hsa-miR-4719 tatATTTGTGcaaatatac
 23
 UCACAAAU m7b (m7b->m6c) 0.559 0.535 No effect
hsa-miR-493-5p tatattTGTACAAatatac
 7
 UUGUACAU m7a Created -0.065 -0.038 No effect
hsa-miR-507 tatatttGTGCAAAtatac
 7
 UUUUGCAC m7b Disrupted -0.099 -0.074 No effect
hsa-miR-557 tatatttGTGCAAAtatac
 7
 GUUUGCAC m7b Disrupted -0.138 -0.085 0.01


Mutation Mutation ID Sample Name Cancer Type
chr2:g.211377676A>T COSN9307504 AOCS-112-1-2 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.211378500C>A COSN1822242 RK063_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1277-5p ggcaaATATATTTtagcag
 20
 AAAUAUAU m8a Created -0.104000 0.099000 -0.080000
hsa-miR-3145-3p ggcAAATATCTtttagcag
 2
 AGAUAUUU m8a Disrupted 0.358000 0.159000 No effect
hsa-miR-1277-5p ggcaaATATATTTtagcag
 20
 AAAUAUAU m8a Created -0.104000 0.099000 -0.080000
hsa-miR-3145-3p ggcAAATATCTtttagcag
 2
 AGAUAUUU m8a Disrupted 0.358000 0.159000 No effect
hsa-miR-1277-5p ggcaaATATATTTtagcag
 0 AAAUAUAU m8a Created -0.104 0.099 -5.29
hsa-miR-3145-3p ggcAAATATCTtttagcag
 0 AGAUAUUU m8a Disrupted 0.358 0.159 -4.4

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211378582A>T COSN6935918 8058184 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-146a-5p agagatctgAGTTCTCtct
 3
 UGAGAACU m7b (m7b->m6b) -0.246000 -0.309000 0.180000
hsa-miR-146b-5p agagatctgAGTTCTCtct
 3
 UGAGAACU m7b (m7b->m6b) -0.246000 -0.309000 No effect
hsa-miR-4330 agagATCTGAGttctctct
 1
 CCUCAGAU m7b Disrupted 0.080000 0.007000 No effect
hsa-miR-5100 agaGATCTGAgttctctct
 0 UUCAGAUC m7b (m7b->m6c) 0.021000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211378704G>A COSN1822243 RK048_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1285-5p tacagaTGAGATCaggcat
 7
 GAUCUCAC m7a Disrupted 0.005000 0.005000 0.070000
hsa-miR-205-3p tacagaTGAAATCaggcat
 10
 GAUUUCAG m7a Created 0.138000 0.138000 0.010000
hsa-miR-29a-5p tacagatgAAATCAGgcat
 7
 ACUGAUUU m7b Created 0.067000 0.155000 -0.060000
hsa-miR-452-3p taCAGATGAGatcaggcat
 1
 CUCAUCUG m8a (m8a->m7b) 0.180000 0.172000 No effect
hsa-miR-4695-3p tacagaTGAGATCAggcat
 2
 UGAUCUCA m8a Disrupted -0.144000 -0.112000 No effect
hsa-miR-1285-5p tacagaTGAGATCaggcat
 7
 GAUCUCAC m7a Disrupted 0.005000 0.005000 0.070000
hsa-miR-205-3p tacagaTGAAATCaggcat
 10
 GAUUUCAG m7a Created 0.138000 0.138000 0.010000
hsa-miR-29a-5p tacagatgAAATCAGgcat
 7
 ACUGAUUU m7b Created 0.067000 0.155000 -0.060000
hsa-miR-452-3p taCAGATGAGatcaggcat
 1
 CUCAUCUG m8a (m8a->m7b) 0.180000 0.172000 No effect
hsa-miR-4695-3p tacagaTGAGATCAggcat
 2
 UGAUCUCA m8a Disrupted -0.144000 -0.112000 No effect
hsa-miR-1285-5p tacagaTGAGATCaggcat
 0 GAUCUCAC m7a Disrupted 0.005 0.005 0.07
hsa-miR-205-3p tacagaTGAAATCaggcat
 0 GAUUUCAG m7a Created 0.138 0.138 -0.65
hsa-miR-29a-5p tacagatgAAATCAGgcat
 0 ACUGAUUU m7b Created 0.067 0.155 -0.06
hsa-miR-452-3p taCAGATGAGatcaggcat
 0 CUCAUCUG m8a (m8a->m7b) 0.18 0.172 No effect
hsa-miR-4695-3p tacagaTGAGATCAggcat
 0 UGAUCUCA m8a Disrupted -0.144 -0.112 No effect


Mutation Mutation ID Sample Name Cancer Type
chr2:g.211378932A>T COSN9873033 C0031T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr2:g.211379055A>G COSN5788185 HX19T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.211379172C>T COSN8278695 ASHPC_0007_Pa_P [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3133 gtgatatGTTCTTTctttt
 0 UAAAGAAC m7b Created -0.049000 0.021000 -0.080000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211379687A>G COSN6167087 RK186_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-145-5p tatAACTGGACagaaccac
 4
 GUCCAGUU m8a Disrupted -0.129000 -0.113000 No effect
hsa-miR-18a-3p tataactGGGCAGaaccac
 6
 ACUGCCCU m6b Created -0.162000 -0.206000 -0.010000
hsa-miR-1913 tataactGGGCAGAaccac
 6
 UCUGCCCC m7a Created -0.071000 -0.116000 -0.140000
hsa-miR-198 tataaCTGGACagaaccac
 5
 GGUCCAGA m6b Disrupted -0.028000 no TS No effect
hsa-miR-324-3p tataactGGGCAGaaccac
 6
 ACUGCCCC m6b Created -0.089000 -0.134000 -0.090000
hsa-miR-4727-5p tataactgGGCAGAaccac
 7
 AUCUGCCA m6b Created -0.109000 -0.131000 No effect
hsa-miR-5195-3p tatAACTGGAcagaaccac
 4
 AUCCAGUU m7b (m7b->m6c) -0.120000 -0.113000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211379919G>T COSN8557951 tumor_4163639 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][diffuse_large_B_cell_lymphoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-325 ctgCTACTAGatgaagttg
 0 CCUAGUAG m7b (m7b->m6c) 0.034000 0.006000 0.370000
hsa-miR-452-3p ctgctactAGATGAagttg
 1
 CUCAUCUG m6b Disrupted 0.180000 0.091000 0.010000
hsa-miR-5007-3p ctgctactATATGAagttg
 6
 AUCAUAUG m6b Created -0.140000 -0.007000 -0.030000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211380881G>T COSN6935919 8034291 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1237 ttggAGAAGGAaaaaatga
 0 UCCUUCUG m7a Disrupted 0.031000 0.009000 No effect
hsa-miR-1248 ttggAGAAGGaaaaaatga
 0 ACCUUCUU m6b Disrupted -0.020000 -0.033000 No effect
hsa-miR-2681-5p ttggagaaGTAAAAaatga
 0 GUUUUACC m6b Created 0.240000 0.343000 -1.420000
hsa-miR-3682-5p ttggAGAAGTAaaaaatga
 2
 CUACUUCU m7b Created 0.171000 0.236000 -0.020000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211380892T>C COSN6167088 RK070_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3174 aatcACTCACTttggagaa
 0 UAGUGAGU m7b Created -0.139000 -0.149000 No effect
hsa-miR-3609 aatcacTCACTTTGgagaa
 7
 CAAAGUGA m8a Created 0.158000 0.293000 -0.010000
hsa-miR-3662 aatcacTCATTTTggagaa
 9
 GAAAAUGA m7b Disrupted 0.769000 0.548000 No effect
hsa-miR-4698 aatcactCATTTTGgagaa
 1
 UCAAAAUG m7b Disrupted 0.582000 0.452000 No effect
hsa-miR-520g aatcactCACTTTGgagaa
 14
 ACAAAGUG m7b Created 0.442000 0.507000 -0.030000
hsa-miR-520h aatcactCACTTTGgagaa
 14
 ACAAAGUG m7b Created 0.442000 0.507000 -0.020000
hsa-miR-548ah-5p aatcacTCACTTTggagaa
 7
 AAAAGUGA m7b Created 0.194000 0.320000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr2:g.211381326T>A COSN9873034 C0058T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.211381441G>A COSN1822244 RK107_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-3p aactcaTTTGGGatataag
 10
 GCCCAAAG m6b Disrupted 0.097000 0.063000 0.030000
hsa-miR-4733-5p aactcatTTGGGATataag
 10
 AAUCCCAA m7b Disrupted -0.093000 -0.025000 0.160000
hsa-miR-5009-3p aactcATTTAGGAtataag
 0 UCCUAAAU m8a Created no TS 0.076000 -0.020000
hsa-miR-186-3p aactcaTTTGGGatataag
 0 GCCCAAAG m6b Disrupted 0.097 0.063 0.03
hsa-miR-4733-5p aactcatTTGGGATataag
 0 AAUCCCAA m7b Disrupted -0.093 -0.025 0.16
hsa-miR-5009-3p aactcATTTAGGAtataag
 0 UCCUAAAU m8a Created no TS 0.076 -0.02

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211381448C>T COSN6935920 8067246 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3646 tcctttaaaTTCATTTggg
 0 AAAAUGAA m7b (m6b->m7b) 0.321000 0.457000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211381466T>C COSN6556656 ICGC_MB104 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-101-3p gttGTACTGTAagatatct
 2
 UACAGUAC m8a Disrupted -0.060000 -0.015000 0.920000
hsa-miR-144-3p gttgTACTGTAagatatct
 0 UACAGUAU m7a Disrupted 0.225000 0.194000 0.510000
hsa-miR-200a-5p gttgtactGTAAGATatct
 1
 CAUCUUAC m7b Disrupted 0.107000 0.062000 0.160000
hsa-miR-200b-5p gttgtactGTAAGATatct
 1
 CAUCUUAC m7b Disrupted 0.111000 0.055000 0.040000
hsa-miR-600 gttgtaCTGTAAGatatct
 1
 ACUUACAG m7b Disrupted -0.002000 no TS 0.070000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211381682T>A 9_12407 CRC-3-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1193 gtaaatccaACCATCCatc
 0 GGGAUGGU m7b (m6b->m7b) -0.074 -0.085 0.01
hsa-miR-1246 gtaAATCCATccatccatc
 2
 AAUGGAUU m7b (m7b->m6c) 0.171 0.126 0.46
hsa-miR-3134 gtaaatccATCCATCcatc
 0 UGAUGGAU m7b Disrupted 0.061 0.079 0.01
hsa-miR-432-3p gtaaatCCATCCAtccatc
 2
 CUGGAUGG m7b Disrupted -0.196 -0.129 0.01
hsa-miR-5004-3p gtaAATCCAAccatccatc
 2
 CUUGGAUU m7b (m6c->m7b) 0.134 0.19 No effect
hsa-miR-92a-1-5p gtaaatCCAACCatccatc
 2
 AGGUUGGG m6b Created no TS -0.035 -0.26

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211382200A>T COSN6167089 RK135_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1248 tgaagtAGAAGGTaactct
 0 ACCUUCUU m7a Disrupted -0.020000 -0.020000 0.010000
hsa-miR-181c-3p tgaagtaGATGGTaactct
 0 AACCAUCG m6b Created no TS -0.057000 -0.240000
hsa-miR-4724-3p tgaagtaGAAGGTAactct
 4
 GUACCUUC m7b Disrupted -0.008000 0.089000 3.250000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211382487G>A COSN1822245 RK086_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4668-3p ctccattttGGATTTTgaa
 9
 GAAAAUCC m7b (m7b->m6b) 0.148000 0.153000 No effect
hsa-miR-4698 ctcCATTTTGgattttgaa
 1
 UCAAAAUG m7b (m7b->m6c) 0.582000 0.496000 No effect
hsa-miR-4668-3p ctccattttGGATTTTgaa
 0 GAAAAUCC m7b (m7b->m6b) 0.148 0.153 No effect
hsa-miR-4698 ctcCATTTTGgattttgaa
 0 UCAAAAUG m7b (m7b->m6c) 0.582 0.496 0.84

Mutation Mutation ID Sample Name Cancer Type
chr2:g.211382901T>C COSN4801666 tumor_4177987 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-106a-3p aatttctaATTGCAaagat
 6
 CUGCAAUG m6b Disrupted -0.044000 no TS 0.690000
hsa-miR-450b-5p aatttctaaTTGCAAAgat
 7
 UUUUGCAA m7b (m7b->m6b) -0.058000 0.011000 0.010000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
211376766 rs190371387 T T hsa-miR-1250-3p
hsa-miR-153-5p
hsa-miR-4695-3p
hsa-miR-6758-3p
8
12
12
13
 tGAAAATGAgatc
tgAAAATGAgatc
tgaaaaTGAGATC
tgaaAATGAGAtc
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 0.07
0.124
-0.115
0.021
211377000 rs1595066 G G hsa-miR-548av-5p
hsa-miR-548k
hsa-miR-8054
15
15
15
 agtaagGTACTTT
agtaagGTACTTT
agtaagGTACTTT
 Disrupted
Disrupted
Disrupted
N
N
N
 0.037
0.037
0.074
A hsa-miR-200a-5p
hsa-miR-200b-5p
hsa-miR-548l
hsa-miR-550b-3p
17
17
15
16
 aGTAAGATActtt
aGTAAGATActtt
agtaagATACTTT
AGTAAGAtacttt
 Created
Created
Created
Created
N
N
N
N
 -0.038
-0.038
0.08
-0.006
211377049 rs116359385 A
A hsa-miR-3674
hsa-miR-4703-3p
0 aaCTACAAAagtt
AACTACAaaagtt
 Disrupted
Disrupted
N
N
 0.03
-0.035
211377211 rs188880275 T T hsa-miR-5093
hsa-miR-875-3p
13
15
 atgtCATTTCCAg
atgtcaTTTCCAG
 Disrupted
Disrupted
N
N
 0.055
0.004
211377422 rs148804822 C C hsa-miR-433-3p
5
 ctatATCATGAga
 Disrupted
N
 0.038
T hsa-miR-1277-5p
hsa-miR-5692b
hsa-miR-5692c
2
5
5
 cTATATTAtgaga
ctATATTATgaga
ctATATTATgaga
 Created
Created
Created
N
N
N
 0.205
0.182
0.182
211377745 rs188409270 C C hsa-let-7a-2-3p
hsa-let-7g-3p
2
2
 gCTGTACAtataa
gCTGTACAtataa
 Disrupted
Disrupted
N
N
 -0.021
-0.021
T hsa-let-7f-2-3p
hsa-miR-1185-1-3p
hsa-miR-1185-2-3p
hsa-miR-190a-3p
hsa-miR-5011-5p
2
2
2
9
9
 gCTGTATAtataa
gCTGTATAtataa
gCTGTATAtataa
gctgtATATATAA
gctgTATATATAa
 Created
Created
Created
Created
Created
N
N
N
N
N
 0.011
0.048
0.048
0.264
0.281
211378028 rs191943813 A A hsa-miR-4330
hsa-miR-4661-3p
hsa-miR-4695-3p
1
1
2
 TCTGAGAtcctac
tctgaGATCCTAc
tcTGAGATCctac
 Disrupted
Disrupted
Disrupted
N
N
N
 0.039
0.013
0.057
T hsa-miR-3914
hsa-miR-8065
1
1
 tctgaGTTCCTAc
tctgagTTCCTAC
 Created
Created
N
N
 0.047
0.042
211378581 rs144018296 G G hsa-miR-146a-5p
hsa-miR-146b-5p
hsa-miR-3925-5p
hsa-miR-4330
hsa-miR-7153-5p
11
11
15
2
11
 atctgAGTTCTCt
atctgAGTTCTCt
atctgaGTTCTCT
ATCTGAGttctct
atctgAGTTCTCt
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
LT
N
N
N
N
 0.063
0.063
0.055
0.073
0.063
A hsa-miR-3123
hsa-miR-3942-3p
hsa-miR-5100
hsa-miR-892c-5p
15
2
2
2
 atctgaATTCTCT
ATCTGAAttctct
ATCTGAAttctct
aTCTGAATtctct
 Created
Created
Created
Created
N
N
N
N
 0.084
0.105
-0.014
0.073
211379012 rs7586570 A A hsa-miR-1246
hsa-miR-1290
hsa-miR-3167
hsa-miR-490-5p
hsa-miR-876-5p
0 tgagaAATCCATg
tgagAAATCCAtg
tgaGAAATCCAtg
tgagaaATCCATG
tgaGAAATCCAtg
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
 0.05
0.079
0.039
0.003
0.039
C hsa-miR-4653-3p
hsa-miR-6514-5p
5
0
 tgagAACTCCAtg
tgagaACTCCATg
 Created
Created
N
N
 -0.008
-0.013
211379238 rs80135897 A A hsa-miR-129-5p
hsa-miR-593-3p
hsa-miR-6818-3p
hsa-miR-6895-3p
21
6
6
6
 agagaCAAAAAAa
AGAGACAaaaaaa
AGAGACAAaaaaa
AGAGACAaaaaaa
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 0.006
-0.029
0.027
-0.004
C hsa-miR-133a-3p
hsa-miR-133b
hsa-miR-6843-3p
hsa-miR-6848-3p
8
8
6
6
 agaGACCAAAaaa
agaGACCAAAaaa
aGAGACCAAaaaa
aGAGACCAAaaaa
 Created
Created
Created
Created
N
N
N
N
 -0.002
-0.002
-0.068
-0.079
211379239 rs74770763 C C hsa-miR-129-5p
hsa-miR-593-3p
hsa-miR-6818-3p
hsa-miR-6895-3p
21
7
7
7
 cagagaCAAAAAA
CAGAGACAaaaaa
cAGAGACAAaaaa
cAGAGACAaaaaa
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 0.168
-0.069
0.027
-0.004
A hsa-miR-3191-5p
hsa-miR-4768-5p
hsa-miR-6809-3p
hsa-miR-6833-3p
7
7
7
7
 CAGAGAAaaaaaa
cAGAGAAAaaaaa
cAGAGAAAaaaaa
cAGAGAAAaaaaa
 Created
Created
Created
Created
N
N
N
N
 -0.001
0.067
0.073
0.071
211379308 rs72947669 A A hsa-miR-194-5p
hsa-miR-379-3p
hsa-miR-380-3p
hsa-miR-411-3p
hsa-miR-4495
hsa-miR-5007-3p
5
5
5
5
5
6
 TGTTACAtatgac
tGTTACATAtgac
tgTTACATAtgac
tGTTACATAtgac
tgTTACATAtgac
tgttaCATATGAc
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
 0.061
0.074
0.101
0.074
0.106
0.027
211379359 rs57527640 A A hsa-miR-5692a
1
 TTATTTAtttttt
 Disrupted
N
 0.168
211379530 rs181061467 A
G hsa-miR-2681-5p
hsa-miR-7153-3p
4
3
 ttgcatGGTAAAA
ttgCATGGTAaaa
 Created
Created
N
N
 -0.023
-0.022
211380035 rs200338466 A A hsa-miR-302a-5p
0 gtGTTTAAGtgtt
 Disrupted
N
 0.074
211380035 rs72546108 - - hsa-miR-302a-5p
0 gtGTTTAAGtgtt
 Unknown
N
 0.073
C hsa-miR-494-3p
hsa-miR-510-3p
0 gTGTTTCAagtgtt
gtGTTTCAAgtgtt
 Unknown
Unknown
N
N
 0.085
0.088
211380036 rs201241931 T T hsa-miR-302a-5p
0 agtGTTTAAGtgt
 Disrupted
N
 0.072
211380036 rs34217661 - - hsa-miR-302a-5p
0 agtGTTTAAGtgt
 Unknown
N
 0.073
C hsa-miR-4773
hsa-miR-5687
0 agTGTTCTAagtgt
agtGTTCTAAgtgt
 Unknown
Unknown
N
N
 0.06
0.04
211380037 rs202225583 C T hsa-miR-302a-5p
0 tagtGTTTAAGtg
 Created
N
 0.072
C hsa-miR-3117-5p
0 TAGTGTCtaagtg
 Disrupted
N
 -0.057
211380037 rs66482268 - - hsa-miR-302a-5p
0 tagtGTTTAAGtg
 Unknown
N
 0.073
C hsa-miR-208a-3p
hsa-miR-208b-3p
hsa-miR-3117-5p
hsa-miR-3617-5p
hsa-miR-499a-5p
hsa-miR-641
0 tagtGTCTTAAgtg
tagtGTCTTAAgtg
TAGTGTCttaagtg
tagTGTCTTAagtg
tagtGTCTTAAgtg
tagTGTCTTAagtg
 Unknown
Unknown
Unknown
Unknown
Unknown
Unknown
N
N
N
N
N
N
 0.048
0.052
-0.062
0.06
0.068
0.056
211380227 rs1836724 T C hsa-miR-28-5p
hsa-miR-3139
hsa-miR-665
hsa-miR-708-5p
21
21
21
21
 cAGCTCCTggttt
cAGCTCCTggttt
cagCTCCTGGttt
cAGCTCCTggttt
 Created
Created
Created
Created
N
N
N
N
 -0.016
0.031
-0.011
0.012
T hsa-miR-335-5p
21
 caGCTCTTGgttt
 Disrupted
N
 0.023
211380666 rs140434825 - - hsa-miR-371a-5p
2
 tcagttGTTTGAG
 Unknown
N
 0.01
A hsa-miR-4637
9
 tcAGTTAGTttgag
 Unknown
N
 -0.011
211382106 rs186127583 A A hsa-miR-130a-5p
hsa-miR-23a-3p
hsa-miR-23b-3p
hsa-miR-23c
hsa-miR-4729
4
4
4
4
4
 aaataAATGTGAA
aaataAATGTGAA
aaataAATGTGAA
aaataAATGTGAA
aaATAAATGtgaa
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
 0.039
0.07
0.081
0.081
0.127
G hsa-miR-216b-3p
hsa-miR-377-3p
4
4
 aaatAAGTGTGAa
aaataaGTGTGAA
 Created
Created
N
N
 -0.021
-0.022
211382401 rs201476901 - TG hsa-miR-3692-3p
10
 agacTGTGGAAAtgc
 Unknown
N
 -0.017
- hsa-miR-145-5p
hsa-miR-3180-5p
hsa-miR-5195-3p
2
2
2
 agACTGGAAatgc
agaCTGGAAAtgc
agACTGGAAatgc
 Unknown
Unknown
Unknown
N
N
N
 -0.039
0.022
-0.039
211382515 rs181464488 T T hsa-miR-3163
hsa-miR-4282
18
17
 taATTTTATttgt
tAATTTTAtttgt
 Disrupted
Disrupted
N
N
 0.107
0.18
C hsa-miR-3646
21
 taatTTCATTTgt
 Created
N
 0.044
211382591 rs16846004 T T hsa-miR-145-5p
hsa-miR-5195-3p
13
13
 ttgAACTGGAAga
ttgAACTGGAAga
 Disrupted
Disrupted
N
N
 -0.057
-0.046
211382600 rs76182521 C C hsa-miR-1246
hsa-miR-4320
6
4
 gggAATCCATtga
ggGAATCCAttga
 Disrupted
Disrupted
N
N
 0.071
-0.018
A hsa-miR-3938
hsa-miR-630
6
4
 GGGAATAcattga
ggGAATACAttga
 Created
Created
N
N
 -0.07
0.026
211382603 rs16846006 A A hsa-miR-1246
hsa-miR-3938
hsa-miR-4320
hsa-miR-642a-5p
6
2
4
3
 tgagggAATCCAT
tgAGGGAATccat
tgaggGAATCCAt
tGAGGGAAtccat
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 0.071
-0.003
-0.018
-0.052
G hsa-miR-6795-3p
hsa-miR-6826-3p
hsa-miR-6887-3p
3
3
3
 tGAGGGGAtccat
tGAGGGGAtccat
tGAGGGGAtccat
 Created
Created
Created
N
N
N
 -0.112
-0.126
-0.08
211382749 rs74983529 C C hsa-miR-1255a
hsa-miR-1255b-5p
3
3
 CTCATCCtttaca
CTCATCCtttaca
 Disrupted
Disrupted
N
N
 -0.148
-0.148
A hsa-miR-1252-3p
hsa-miR-1272
hsa-miR-3646
3
2
3
 ctcaTCATTTAca
cTCATCATttaca
ctcaTCATTTAca
 Created
Created
Created
N
N
N
 0.085
-0.048
0.086
211383099 rs187665528 A A hsa-miR-205-3p
hsa-miR-3942-3p
3
2
 tCTGAAATtgaga
TCTGAAAttgaga
 Disrupted
Disrupted
N
N
 -0.019
-0.046
C hsa-miR-5000-5p
hsa-miR-513c-5p
hsa-miR-514b-5p
3
7
7
 tCTGAACTtgaga
tctgaaCTTGAGA
tctgaaCTTGAGA
 Created
Created
Created
N
N
N
 -0.125
-0.154
-0.179
211383135 rs79310613 G
A hsa-miR-129-5p
1
 aCAAAAAAataac
 Created
N
 0.026

Genome Browser