SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_024007
Gene Symbol: EBF1
Description: Homo sapiens early B-cell factor 1 (EBF1), mRNA.
Gene Location: chr5(-):158122922-158526788
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr5:g.158696189A>C COSN2080121 RK180_C02 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr5:g.158697214T>G COSN14859341 LP2000108-DNA_A01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Mutation Mutation ID Sample Name Cancer Type
chr5:g.158697232T>A COSN14587156 8067507 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr5:g.158698030A>G COSN9930352 C0007T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-224-3p acccttACCATTTgtaaca
 7
 AAAAUGGU m7b Disrupted 0.002000 no TS 0.080000
hsa-miR-522-3p acccttACCATTTgtaaca
 7
 AAAAUGGU m7b Disrupted 0.020000 no TS No effect
hsa-miR-553 acccttACCGTTTgtaaca
 0 AAAACGGU m7b Created no TS -0.104000 -1.220000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.158698653A>T COSN8492202 742_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2681-5p aaaaaaaGGTAAAAaaaaa
 0 GUUUUACC m7b Created -0.039000 -0.251000 -0.410000
hsa-miR-4724-3p aaaaaAAGGTAaaaaaaaa
 0 GUACCUUC m6b Created no TS -0.128000 -0.560000
hsa-miR-2681-5p aaaaaaaGGTAAAAaaaaa
 0 GUUUUACC m7b Created -0.039000 -0.251000 -0.410000
hsa-miR-4724-3p aaaaaAAGGTAaaaaaaaa
 0 GUACCUUC m6b Created no TS -0.128000 -0.560000
hsa-miR-2681-5p aaaaaaaGGTAAAAaaaaa
 0 GUUUUACC m7b Created -0.039000 -0.251000 -0.410000
hsa-miR-4724-3p aaaaaAAGGTAaaaaaaaa
 0 GUACCUUC m6b Created no TS -0.128000 -0.560000
hsa-miR-2681-5p aaaaaaaGGTAAAAaaaaa
 0 GUUUUACC m7b Created -0.039000 -0.251000 -0.410000
hsa-miR-4724-3p aaaaaAAGGTAaaaaaaaa
 0 GUACCUUC m6b Created no TS -0.128000 -0.560000


Mutation Mutation ID Sample Name Cancer Type
chr5:g.158698655G>A COSN15350674 SNU_WGS_09_S1 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr5:g.158699047T>C COSN6870005 RK190_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2115-3p gtaaTCTGATacaagtccc
 13
 CAUCAGAA m6b Disrupted -0.079000 no TS 0.070000
hsa-miR-361-5p gtaaTCTGATAcaagtccc
 13
 UUAUCAGA m7b Disrupted -0.169000 no TS 0.060000
hsa-miR-581 gtaatctgACACAAGtccc
 2
 UCUUGUGU m7b Created -0.133000 -0.275000 -0.020000
hsa-miR-592 gtaatcTGACACAAgtccc
 0 UUGUGUCA m8a Created no TS -0.310000 -0.010000
hsa-miR-597 gtaatcTGACACAagtccc
 0 UGUGUCAC m7a Created no TS -0.149000 -0.760000
hsa-miR-599 gtaatctGACACAAgtccc
 0 GUUGUGUC m7b Created no TS -0.165000 -1.290000
hsa-miR-643 gtaatctgATACAAGTccc
 0 ACUUGUAU m8a Disrupted -0.246000 -0.132000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
158696899 rs187371078 A
C hsa-miR-5010-3p
hsa-miR-599
3
3
 aaaaaACACAAAg
aaaaaACACAAAg
 Created
Created
N
N
 -0.083
-0.025
158698653 rs201485990 A
T hsa-miR-2681-5p
hsa-miR-4724-3p
hsa-miR-6782-3p
1
1
1
 aaaaGGTAAAAAa
aaAAGGTAAaaaa
aAAAGGTAaaaaa
 Created
Created
Created
N
N
N
 -0.212
-0.128
-0.101
158698654 rs112280787 G
T hsa-miR-2681-5p
hsa-miR-5003-3p
1
1
 aaaaaGTAAAAAa
aAAAAGTAaaaaa
 Created
Created
N
N
 -0.026
-0.024

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