SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_006482
Gene Symbol: DYRK2
Description: Homo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2), transcript variant 1, mRNA.
Gene Location: chr12(+):68042511-68056444
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr12:g.67659020G>A COSN1582136 RK126_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-147a gactgCCACACAtttacag
 0 GUGUGUGG m7b Created no TS -0.171000 No effect
hsa-miR-644a gactGCCACACatttacag
 0 AGUGUGGC m7b Created no TS -0.436000 No effect
hsa-miR-147a gactgCCACACAtttacag
 0 GUGUGUGG m7b Created no TS -0.171 No effect
hsa-miR-644a gactGCCACACatttacag
 0 AGUGUGGC m7b Created no TS -0.436 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.67660302G>A COSN9754277 C0004T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1304-3p tggtcccCAGTGAGgccaa
 12
 UCUCACUG m7b Disrupted 0.112000 no TS 1.560000
hsa-miR-450a-3p tggTCCCCAATgaggccaa
 6
 AUUGGGGA m8a Created -0.209000 -0.170000 -0.100000
hsa-miR-4667-5p tggTCCCCAGTgaggccaa
 0 ACUGGGGA m8a Disrupted -0.167000 -0.203000 0.030000
hsa-miR-4700-5p tggTCCCCAGtgaggccaa
 0 UCUGGGGA m7b (m7b->m6b) -0.188000 -0.215000 0.040000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.67661030A>G COSN8586572 J10_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3617 tttgagacTGTCTTTattt
 19
 AAAGACAU m7a Created -0.004000 -0.004000 No effect
hsa-miR-4474-5p tttGAGACTAtctttattt
 1
 UUAGUCUC m7b (m7b->m6b) -0.100000 no TS 0.380000
hsa-miR-4662a-3p tttgagaCTATCTTTattt
 16
 AAAGAUAG m8a Disrupted 0.062000 0.076000 0.010000
hsa-miR-548u tttgagactGTCTTTattt
 0 CAAAGACU m6b Created no TS 0.069000 -0.100000
hsa-miR-641 tttgagacTGTCTTTattt
 19
 AAAGACAU m7a Created -0.004000 -0.004000 0.160000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.67661179C>A COSN9473898 AOCS-130-1-0 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-34a-3p atagaGCTGATTtaataaa
 2
 CAAUCAGC m7b Created -0.028000 -0.123000 No effect
hsa-miR-4422 atagagcTGCTTTaataaa
 0 AAAAGCAU m6b Disrupted -0.111000 -0.177000 No effect
hsa-miR-4660 ataGAGCTGCtttaataaa
 6
 UGCAGCUC m7b (m7b->m6b) -0.283000 -0.108000 0.240000
hsa-miR-551b-5p atagagcTGATTTaataaa
 11
 GAAAUCAA m6b Created 0.176000 0.303000 No effect
hsa-miR-646 atagAGCTGCTTtaataaa
 7
 AAGCAGCU m8a Disrupted -0.077000 no TS No effect
hsa-miR-9-3p atagagctGCTTTAataaa
 0 AUAAAGCU m6b Disrupted -0.020000 -0.088000 0.190000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.67662277A>G COSN7618556 PCSI_0083_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4708-5p ggggcttgtGCATCTCTct
 0 AGAGAUGC m8a (m7b->m8a) 0.053000 -0.121000 -3.250000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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