| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_144729 |
|---|---|
| Gene Symbol: | DUSP10 |
| Description: | Homo sapiens dual specificity phosphatase 10 (DUSP10), transcript variant 1, mRNA. |
| Gene Location: | chr1(-):221874763-221915516 |
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| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr1:g.221701498G>A | COSN7205077 | 8012211 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-129-5p |
atatttttcGCAAAAAaaa |
15 |
CUUUUUGC | m7b | (m7b->m6b) | -0.215000 | -0.016000 |
0.300000 |
| hsa-miR-2113 |
atatttttCACAAAaaaaa |
0 | AUUUGUGC | m6b | Created | no TS | -0.116000 |
-0.010000 |
| hsa-miR-3611 |
atatttTTCACAAaaaaaa |
0 | UUGUGAAG | m7a | Created | no TS | -0.162000 |
-6.050000 |
| hsa-miR-450a-5p |
atattttTCGCAAAAaaaa |
15 |
UUUUGCGA | m8a | Disrupted | -0.615000 | no TS |
1.030000 |
| hsa-miR-5010-3p |
atatttttCACAAAAaaaa |
0 | UUUUGUGU | m7a | Created | no TS | -0.130000 |
-0.150000 |
| hsa-miR-758 |
atattttTCACAAAaaaaa |
0 | UUUGUGAC | m7a | Created | no TS | -0.165000 |
-1.340000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 221701499 | rs192745297 | C | C |
hsa-miR-450a-5p |
17 |
attttTCGCAAAA |
Disrupted |
N |
-0.615 |
| T |
hsa-miR-1468-3p hsa-miR-3613-3p hsa-miR-3680-3p hsa-miR-450b-5p hsa-miR-507 hsa-miR-518a-5p hsa-miR-527 hsa-miR-548aj-5p hsa-miR-548aw hsa-miR-548f-5p hsa-miR-548g-5p hsa-miR-548x-5p hsa-miR-557 |
17 17 19 17 19 15 15 17 15 17 17 17 19 |
attTTTTGCAaaa aTTTTTTGcaaaa atttttTGCAAAA attttTTGCAAAA atttttTGCAAAA atttTTTGCAAaa atttTTTGCAAaa attTTTTGCAaaa attTTTTGCAAaa attTTTTGCAaaa attTTTTGCAaaa attTTTTGCAaaa atttttTGCAAAA |
Created Created Created Created Created Created Created Created Created Created Created Created Created |
N N N N N N N N N N N N N |
-0.121 -0.095 -0.132 -0.357 -0.14 -0.135 -0.135 -0.117 -0.336 -0.114 -0.117 -0.117 -0.14 |