SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_175848
Gene Symbol: DNMT3B
Description: Homo sapiens DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B), transcript variant 7, mRNA.
Gene Location: chr20(+):31350190-31397162
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr20:g.32807932T>C COSN1869824 RK108_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-329 ccactggGGTGTGTggcag
 0 AACACACC m7b Disrupted -0.064000 no TS 1.960000
hsa-miR-362-3p ccactggGGTGTGTggcag
 0 AACACACC m7b Disrupted -0.064000 no TS 0.640000
hsa-miR-329 ccactggGGTGTGTggcag
 0 AACACACC m7b Disrupted -0.064 no TS 1.96
hsa-miR-362-3p ccactggGGTGTGTggcag
 0 AACACACC m7b Disrupted -0.064 no TS 0.64

Mutation Mutation ID Sample Name Cancer Type
chr20:g.32808309T>G COSN9125903 AOCS-155-3-5 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4421 ccaAGACAGGTattgcaag
 0 ACCUGUCU m8a Created no TS -0.229000 -0.350000
hsa-miR-5699 ccaAGACAGGtattgcaag
 0 UCCUGUCU m7b (m6b->m7b) no TS -0.219000 -1.180000

Mutation Mutation ID Sample Name Cancer Type
chr20:g.32808502G>T COSN1869825 RK209_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1973 ctggagtcTGCACGGgacc
 0 ACCGUGCA m7b Disrupted -0.220000 no TS 0.840000
hsa-miR-3166 ctggaGTCTGCacgggacc
 2
 CGCAGACA m6b Disrupted -0.066000 no TS 4.210000
hsa-miR-4432 ctgGAGTCTTcacgggacc
 0 AAAGACUC m7b (m6b->m7b) no TS -0.021000 -0.080000
hsa-miR-4771 ctggAGTCTGCacgggacc
 2
 AGCAGACU m7b Disrupted -0.372000 -0.173000 3.570000

Mutation Mutation ID Sample Name Cancer Type
chr20:g.32808557G>A COSN15034566 LP6005409-DNA_H01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1272 agggatgaCATCATCatca
 11
 GAUGAUGA m7a Created -0.007000 -0.062000 1.340000
hsa-miR-1322 agggatgaCATCATCatca
 0 GAUGAUGC m7a Created NA NA -0.060000
hsa-miR-2964a-5p agggatGACATCatcatca
 0 AGAUGUCC m6b Created no TS -0.073000 No effect
hsa-miR-4757-3p agggatgACGTCATcatca
 2
 CAUGACGU m7b Disrupted -0.148000 no TS 1.110000
hsa-miR-598 agggATGACGTcatcatca
 0 UACGUCAU m7b Disrupted -0.113000 no TS 1.210000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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