SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001164544
Gene Symbol: DISC1
Description: Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Lv, mRNA.
Gene Location: chr1(+):231762560-231954990
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr1:g.231818549T>C COSN1435560 RK001_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-16-2-3p ccggcaagATATTGatgat
 1
 CCAAUAUU m6b Disrupted -0.014000 no TS 1.380000
hsa-miR-195-3p ccggcaagATATTGatgat
 1
 CCAAUAUU m6b Disrupted -0.011000 no TS 3.390000
hsa-miR-431-5p ccgGCAAGACAttgatgat
 0 UGUCUUGC m8a Created no TS -0.339000 -1.160000

Mutation Mutation ID Sample Name Cancer Type
chr1:g.231819192C>T COSN14564589 8064157 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3143 aataAATGTTATttactaa
 0 AUAACAUU m8a Created no TS -0.184000 -1.340000
hsa-miR-3646 aataaatgTCATTTactaa
 1
 AAAAUGAA m6b Disrupted -0.037000 no TS 0.330000
hsa-miR-543 aataAATGTTatttactaa
 1
 AAACAUUC m6b Created -0.070000 -0.137000 -0.480000
hsa-miR-5692a aataaatgTTATTTactaa
 7
 CAAAUAAU m6b Created 0.043000 0.068000 -2.330000
hsa-miR-3143 aataAATGTTATttactaa
 0 AUAACAUU m8a Created no TS -0.184000 -1.340000
hsa-miR-3646 aataaatgTCATTTactaa
 1
 AAAAUGAA m6b Disrupted -0.037000 no TS 0.330000
hsa-miR-543 aataAATGTTatttactaa
 1
 AAACAUUC m6b Created -0.070000 -0.137000 -0.480000
hsa-miR-5692a aataaatgTTATTTactaa
 7
 CAAAUAAU m6b Created 0.043000 0.068000 -2.330000
hsa-miR-3143 aataAATGTTATttactaa
 0 AUAACAUU m8a Created no TS -0.184000 -1.340000
hsa-miR-3646 aataaatgTCATTTactaa
 1
 AAAAUGAA m6b Disrupted -0.037000 no TS 0.330000
hsa-miR-543 aataAATGTTatttactaa
 1
 AAACAUUC m6b Created -0.070000 -0.137000 -0.480000
hsa-miR-5692a aataaatgTTATTTactaa
 7
 CAAAUAAU m6b Created 0.043000 0.068000 -2.330000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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