SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_145695
Gene Symbol:	DGKB
Description:	Homo sapiens diacylglycerol kinase, beta 90kDa (DGKB), transcript variant 1, mRNA.
Gene Location:	chr7(-):14215605-14881075
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Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr7:g.14176029T>G			0_271				Prostate cancer
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-583	agggagaCCTCTTTGaaag	5	CAAAGAGG	m8a	Disrupted	-0.388	-0.192	0.03

Mutation			Mutation ID		Sample Name		Cancer Type
chr7:g.14176185A>C			COSN15247149		LP6007420-DNA_A01		[oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4635	tttcCTTCAAGttacttac	4	UCUUGAAG	m7b	Disrupted	-0.153000	no TS	0.840000

Mutation			Mutation ID		Sample Name		Cancer Type
chr7:g.14176778A>G			COSN8405674		tumor_4163639		[haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][diffuse_large_B_cell_lymphoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-374c-3p	tttgaCTAAGTaaccacaa	3	CACUUAGC	m6b	Created	-0.120000	-0.228000	-0.250000
hsa-miR-409-5p	tttgactaaGTAACCacaa	0	AGGUUACC	m6b	Created	no TS	-0.189000	-4.020000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
14176616	rs193084573	G	G	hsa-miR-374c-3p	3	gcCTAAGTAtaaa	Disrupted	N	-0.12
			A	hsa-miR-6083	2	gcctaaATATAAA	Created	N	-0.005

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