SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_013994
Gene Symbol: DDR1
Description: Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 4, mRNA.
Gene Location: chr6(+):30856464-30867933
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr6:g.30899321T>G COSN2159336 RK091_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-125a-5p gcccctccCTCAGGGAgcg
 0 UCCCUGAG m8a Disrupted -0.299000 no TS 2.720000
hsa-miR-125b-5p gcccctccCTCAGGGAgcg
 0 UCCCUGAG m8a Disrupted -0.288000 no TS 4.370000
hsa-miR-1321 gccCCTCCCTcagggagcg
 2
 CAGGGAGG m7b (m7b->m6b) -0.133000 no TS 1.070000
hsa-miR-149-3p gcCCCTCCCTcagggagcg
 2
 AGGGAGGG m8a (m8a->m7a) -0.373000 -0.343000 -0.090000
hsa-miR-345-3p gcccctcccTCAGGGagcg
 0 GCCCUGAA m6b Disrupted -0.122000 no TS 23.220000
hsa-miR-4319 gcccctccCTCAGGGAgcg
 0 UCCCUGAG m8a Disrupted -0.309000 no TS 5.020000
hsa-miR-4324 gcccctccCTCAGGGagcg
 0 CCCUGAGA m7a Disrupted NA NA 1.850000
hsa-miR-4419a gcccCTCCCTCAgggagcg
 2
 UGAGGGAG m8a Disrupted -0.305000 no TS 2.220000
hsa-miR-4510 gcccCTCCCTCAgggagcg
 2
 UGAGGGAG m8a Disrupted -0.305000 no TS 10.870000
hsa-miR-4732-3p gcccctcccTCAGGGagcg
 0 GCCCUGAC m6b Disrupted -0.106000 no TS 1.980000
hsa-miR-4734 gcccctCCCGCAGggagcg
 0 GCUGCGGG m7b Created no TS -0.251000 -0.090000
hsa-miR-4739 gccCCTCCCTcagggagcg
 2
 AAGGGAGG m7b (m7b->m6b) -0.133000 no TS No effect
hsa-miR-4756-5p gccCCTCCCTcagggagcg
 2
 CAGGGAGG m7b (m7b->m6b) -0.123000 no TS 0.010000
hsa-miR-544b gcccctcCCTCAGGgagcg
 0 ACCUGAGG m7b Disrupted -0.147000 no TS 8.680000
hsa-miR-670 gcccctcccTCAGGGAgcg
 0 GUCCCUGA m7b (m7b->m6c) -0.072000 no TS 4.390000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.30899394C>T COSN1331063 BN24T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-149-3p ttcCCCTCCCgacagccca
 2
 AGGGAGGG m7b (m7b->m6b) -0.373000 -0.167000 -0.270000
hsa-miR-4433-3p ttcccCTCCTGacagccca
 0 ACAGGAGU m6b Created no TS -0.085000 0.030000
hsa-miR-4459 ttccCCTCCTGacagccca
 0 CCAGGAGG m7b Created no TS -0.309000 -1.350000
hsa-miR-4695-5p ttccCCTCCTGacagccca
 0 CAGGAGGC m7a Created NA NA -1.990000
hsa-miR-4728-5p ttcCCCTCCCgacagccca
 2
 UGGGAGGG m7b (m7b->m6b) -0.382000 -0.167000 -0.570000
hsa-miR-4768-3p ttcccCTCCTGacagccca
 0 CCAGGAGA m6b Created no TS -0.079000 -1.110000
hsa-miR-4779 ttcCCCTCCTgacagccca
 2
 UAGGAGGG m7b (m6b->m7b) -0.152000 -0.304000 -0.130000
hsa-miR-149-3p ttcCCCTCCCgacagccca
 2
 AGGGAGGG m7b (m7b->m6b) -0.373000 -0.167000 -0.270000
hsa-miR-4433-3p ttcccCTCCTGacagccca
 0 ACAGGAGU m6b Created no TS -0.085000 0.030000
hsa-miR-4459 ttccCCTCCTGacagccca
 0 CCAGGAGG m7b Created no TS -0.309000 -1.350000
hsa-miR-4695-5p ttccCCTCCTGacagccca
 0 CAGGAGGC m7a Created NA NA -1.990000
hsa-miR-4728-5p ttcCCCTCCCgacagccca
 2
 UGGGAGGG m7b (m7b->m6b) -0.382000 -0.167000 -0.570000
hsa-miR-4768-3p ttcccCTCCTGacagccca
 0 CCAGGAGA m6b Created no TS -0.079000 -1.110000
hsa-miR-4779 ttcCCCTCCTgacagccca
 2
 UAGGAGGG m7b (m6b->m7b) -0.152000 -0.304000 -0.130000
hsa-miR-149-3p ttcCCCTCCCgacagccca
 2
 AGGGAGGG m7b (m7b->m6b) -0.373 -0.167 -0.27
hsa-miR-4433-3p ttcccCTCCTGacagccca
 0 ACAGGAGU m6b Created no TS -0.085 0.03
hsa-miR-4459 ttccCCTCCTGacagccca
 0 CCAGGAGG m7b Created no TS -0.309 -1.35
hsa-miR-4695-5p ttccCCTCCTGacagccca
 0 CAGGAGGC m7a Created NA NA -1.99
hsa-miR-4728-5p ttcCCCTCCCgacagccca
 2
 UGGGAGGG m7b (m7b->m6b) -0.382 -0.167 -0.57
hsa-miR-4768-3p ttcccCTCCTGacagccca
 0 CCAGGAGA m6b Created no TS -0.079 -1.11
hsa-miR-4779 ttcCCCTCCTgacagccca
 0 UAGGAGGG m7b (m6b->m7b) -0.152 -0.304 -0.13

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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