SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_012137
Gene Symbol:	DDAH1
Description:	Homo sapiens dimethylarginine dimethylaminohydrolase 1 (DDAH1), transcript variant 2, mRNA.
Gene Location:	chr1(-):85784167-85930889
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.85318754G>C			COSN8309202		TCGA-BH-A0B6-01		[breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-452-5p	taaggtAAACAGTTgcatg	0	AACUGUUU	m8a	Created	no TS	-0.077000	-0.110000
hsa-miR-4676-3p	taaggtAAACAGTtgcatg	0	CACUGUUU	m7b	Created	no TS	-0.114000	-0.110000

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.85320483C>T			COSN6471348		CHC205T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-224-5p	acccTGACTTaccgtattt	0	CAAGUCAC	m6b	Created	no TS	0.039000	-0.730000
hsa-miR-5702	accCTGACTCAccgtattt	0	UGAGUCAG	m8a	Disrupted	-0.074000	no TS	2.520000

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.85320745A>C			COSN6048628		RK308_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-2682-3p	taactacacAGAGGCacat	9	CGCCUCUU	m6b	Disrupted	-0.081000	no TS	5.870000

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.85321218A>C			COSN8512225		AOCS-166-1-2		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3194-3p	aagataCAGAGCTaatgaa	0	AGCUCUGC	m7a	Disrupted	NA	NA	0.010000
hsa-miR-4999-5p	aagATACAGCgctaatgaa	0	UGCUGUAU	m7b	(m6c->m7b)	no TS	-0.206000	-0.520000

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.85321428C>T			COSN10055190		C0021T		[kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1202	cccggttGCTGGCAagacc	0	GUGCCAGC	m7b	Created	no TS	-0.455000	-5.800000
hsa-miR-3194-5p	cccggttGCTGGCaagacc	3	GGCCAGCC	m6b	Created	-0.257000	-0.435000	-1.510000
hsa-miR-3972	cccggttGCTGGCAagacc	0	CUGCCAGC	m7b	Created	no TS	-0.403000	-0.120000
hsa-miR-4776-3p	cccggttgcTGGCAAGacc	10	CUUGCCAU	m7a	(m6a->m7a)	-0.014000	-0.014000	-0.010000

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.85321435C>G			COSN15322852		SNUH_G76_S1		[haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4532	agtccCCCCGGGttgccgg	0	CCCCGGGG	m7b	Created	no TS	0.000000	No effect
hsa-miR-4655-5p	agtcccCCCCGGTtgccgg	1	CACCGGGG	m7b	Disrupted	0.000000	no TS	No effect
hsa-miR-4532	agtccCCCCGGGttgccgg	0	CCCCGGGG	m7b	Created	no TS	0.000000	No effect
hsa-miR-4655-5p	agtcccCCCCGGTtgccgg	1	CACCGGGG	m7b	Disrupted	0.000000	no TS	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.85321441C>A			COSN15323990		SNUH_G76_S1		[haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4522	ctgCAGAGTCccccccggt	7	UGACUCUG	m7b	(m7b->m6c)	0.000000	no TS	No effect
hsa-miR-4652-5p	ctgcagAGTCCCCcccggt	1	AGGGGACU	m7b	Disrupted	0.000000	no TS	No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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