SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_022802
Gene Symbol: CTBP2
Description: Homo sapiens C-terminal binding protein 2 (CTBP2), transcript variant 3, mRNA.
Gene Location: chr10(-):126676417-126716453
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.124988347->A ICGC_ssm_v2_129929 HX16T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5003-3p caataAAAAGTAattaaaa
 0 UACUUUUC m7a Disrupted -0.042000 -0.035000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.124988984G>C COSN1114035 HX16T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-214-3p gtacaggCTGCTGTacaga
 0 ACAGCAGG m7a Disrupted NA NA No effect
hsa-miR-3120-3p gtacaggcTGCTGTacaga
 0 CACAGCAA m6b Disrupted -0.039000 no TS 2.820000
hsa-miR-4433-3p gtacaggCTCCTGTacaga
 0 ACAGGAGU m7a Created NA NA -1.070000
hsa-miR-4700-3p gtacaggcTCCTGTacaga
 0 CACAGGAC m6b Created no TS -0.055000 -0.250000
hsa-miR-214-3p gtacaggCTGCTGTacaga
 0 ACAGCAGG m7a Disrupted NA NA No effect
hsa-miR-3120-3p gtacaggcTGCTGTacaga
 0 CACAGCAA m6b Disrupted -0.039000 no TS 2.820000
hsa-miR-4433-3p gtacaggCTCCTGTacaga
 0 ACAGGAGU m7a Created NA NA -1.070000
hsa-miR-4700-3p gtacaggcTCCTGTacaga
 0 CACAGGAC m6b Created no TS -0.055000 -0.250000
hsa-miR-214-3p gtacaggCTGCTGTacaga
 0 ACAGCAGG m7a Disrupted NA NA No effect
hsa-miR-3120-3p gtacaggcTGCTGTacaga
 0 CACAGCAA m6b Disrupted -0.039 no TS 2.82
hsa-miR-4433-3p gtacaggCTCCTGTacaga
 0 ACAGGAGU m7a Created NA NA -1.07
hsa-miR-4700-3p gtacaggcTCCTGTacaga
 0 CACAGGAC m6b Created no TS -0.055 -0.25

Mutation Mutation ID Sample Name Cancer Type
chr10:g.124988989A>C COSN1114037 HX16T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-486-5p agacaGTACAGGctgctgt
 9
 UCCUGUAC m7b Disrupted -0.143000 no TS No effect
hsa-miR-486-5p agacaGTACAGGctgctgt
 9
 UCCUGUAC m7b Disrupted -0.143000 no TS No effect
hsa-miR-486-5p agacaGTACAGGctgctgt
 0 UCCUGUAC m7b Disrupted -0.143 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr10:g.124989018->T ICGC_ssm_v2_37183 HX10T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1265 gtggtagACATCCTGcacgc
 0 CAGGAUGU m8a Created no TS -0.065000 -0.040000
hsa-miR-3665 gtggtagaCACCTGCacgc
 0 AGCAGGUG m7b Disrupted -0.297000 no TS 8.270000
hsa-miR-3934 gtggtagACACCTGcacgc
 0 UCAGGUGU m7b Disrupted -0.094000 no TS -0.160000
hsa-miR-657 gtggtagacACCTGCacgc
 0 GGCAGGUU m6b Disrupted -0.117000 no TS 0.370000
hsa-miR-764 gtggtagaCACCTGCacgc
 0 GCAGGUGC m7a Disrupted NA NA 0.750000

Mutation Mutation ID Sample Name Cancer Type
chr10:g.124989494C>T COSN4895199 CPCG_0183_Pr_P_P3 [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3200-5p aggtaatcaCTCAGATaca
 1
 AAUCUGAG m7b (m7b->m6b) -0.321000 -0.095000 0.030000
hsa-miR-4765 aggtaATCACTCAgataca
 2
 UGAGUGAU m8a Disrupted -0.369000 no TS 0.140000
hsa-miR-5187-3p aggtaatcATTCAGataca
 0 ACUGAAUC m6b Created no TS -0.082000 No effect
hsa-miR-3200-5p aggtaatcaCTCAGATaca
 0 AAUCUGAG m7b (m7b->m6b) -0.321 -0.095 0.03
hsa-miR-4765 aggtaATCACTCAgataca
 0 UGAGUGAU m8a Disrupted -0.369 no TS 0.14
hsa-miR-5187-3p aggtaatcATTCAGataca
 0 ACUGAAUC m6b Created no TS -0.082 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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