| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_001083914 |
|---|---|
| Gene Symbol: | CTBP2 |
| Description: | Homo sapiens C-terminal binding protein 2 (CTBP2), transcript variant 3, mRNA. |
| Gene Location: | chr10(-):126676417-126849624 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.124988347->A | ICGC_ssm_v2_129929 | HX16T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-5003-3p |
caataAAAAGTAattaaaa |
0 | UACUUUUC | m7a | Disrupted | -0.042000 | -0.035000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.124988984G>C | COSN1114035 | HX16T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-214-3p |
gtacaggCTGCTGTacaga |
0 | ACAGCAGG | m7a | Disrupted | NA | NA | No effect | |
| hsa-miR-3120-3p |
gtacaggcTGCTGTacaga |
0 | CACAGCAA | m6b | Disrupted | -0.039000 | no TS |
2.820000 |
|
| hsa-miR-4433-3p |
gtacaggCTCCTGTacaga |
0 | ACAGGAGU | m7a | Created | NA | NA |
-1.070000 |
|
| hsa-miR-4700-3p |
gtacaggcTCCTGTacaga |
0 | CACAGGAC | m6b | Created | no TS | -0.055000 |
-0.250000 |
|
| hsa-miR-214-3p |
gtacaggCTGCTGTacaga |
0 | ACAGCAGG | m7a | Disrupted | NA | NA | No effect | |
| hsa-miR-3120-3p |
gtacaggcTGCTGTacaga |
0 | CACAGCAA | m6b | Disrupted | -0.039000 | no TS |
2.820000 |
|
| hsa-miR-4433-3p |
gtacaggCTCCTGTacaga |
0 | ACAGGAGU | m7a | Created | NA | NA |
-1.070000 |
|
| hsa-miR-4700-3p |
gtacaggcTCCTGTacaga |
0 | CACAGGAC | m6b | Created | no TS | -0.055000 |
-0.250000 |
|
| hsa-miR-214-3p |
gtacaggCTGCTGTacaga |
0 | ACAGCAGG | m7a | Disrupted | NA | NA | No effect | |
| hsa-miR-3120-3p |
gtacaggcTGCTGTacaga |
0 | CACAGCAA | m6b | Disrupted | -0.039 | no TS |
2.82 |
|
| hsa-miR-4433-3p |
gtacaggCTCCTGTacaga |
0 | ACAGGAGU | m7a | Created | NA | NA |
-1.07 |
|
| hsa-miR-4700-3p |
gtacaggcTCCTGTacaga |
0 | CACAGGAC | m6b | Created | no TS | -0.055 |
-0.25 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.124988989A>C | COSN1114037 | HX16T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-486-5p |
agacaGTACAGGctgctgt |
9 |
UCCUGUAC | m7b | Disrupted | -0.143000 | no TS | No effect | |
| hsa-miR-486-5p |
agacaGTACAGGctgctgt |
9 |
UCCUGUAC | m7b | Disrupted | -0.143000 | no TS | No effect | |
| hsa-miR-486-5p |
agacaGTACAGGctgctgt |
0 | UCCUGUAC | m7b | Disrupted | -0.143 | no TS | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr10:g.124989018->T | ICGC_ssm_v2_37183 | HX10T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1265 |
gtggtagACATCCTGcacgc |
0 | CAGGAUGU | m8a | Created | no TS | -0.065000 |
-0.040000 |
|
| hsa-miR-3665 |
gtggtagaCACCTGCacgc |
0 | AGCAGGUG | m7b | Disrupted | -0.297000 | no TS |
8.270000 |
|
| hsa-miR-3934 |
gtggtagACACCTGcacgc |
0 | UCAGGUGU | m7b | Disrupted | -0.094000 | no TS |
-0.160000 |
|
| hsa-miR-657 |
gtggtagacACCTGCacgc |
0 | GGCAGGUU | m6b | Disrupted | -0.117000 | no TS |
0.370000 |
|
| hsa-miR-764 |
gtggtagaCACCTGCacgc |
0 | GCAGGUGC | m7a | Disrupted | NA | NA |
0.750000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr10:g.124989494C>T | COSN4895199 | CPCG_0183_Pr_P_P3 | [prostate][NS][carcinoma][adenocarcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3200-5p |
aggtaatcaCTCAGATaca |
1 |
AAUCUGAG | m7b | (m7b->m6b) | -0.321000 | -0.095000 |
0.030000 |
| hsa-miR-4765 |
aggtaATCACTCAgataca |
2 |
UGAGUGAU | m8a | Disrupted | -0.369000 | no TS |
0.140000 |
| hsa-miR-5187-3p |
aggtaatcATTCAGataca |
0 | ACUGAAUC | m6b | Created | no TS | -0.082000 | No effect |
| hsa-miR-3200-5p |
aggtaatcaCTCAGATaca |
0 | AAUCUGAG | m7b | (m7b->m6b) | -0.321 | -0.095 |
0.03 |
| hsa-miR-4765 |
aggtaATCACTCAgataca |
0 | UGAGUGAU | m8a | Disrupted | -0.369 | no TS |
0.14 |
| hsa-miR-5187-3p |
aggtaatcATTCAGataca |
0 | ACUGAAUC | m6b | Created | no TS | -0.082 | No effect |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 124988345 | rs202127289 | A | A |
hsa-miR-5003-3p |
14 |
AAAAGTAattaaa |
Disrupted |
N |
-0.007 |
| G |
hsa-miR-34b-3p |
6 |
aaaAGTGATTAaa |
Created |
N |
-0.251 |
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| 124988348 | rs116386748 | A | A |
hsa-miR-5003-3p |
14 |
ataAAAAGTAatt |
Disrupted |
N |
-0.007 |
| 124988884 | rs76965935 | A | A |
hsa-miR-5003-3p |
18 |
aaaaAAAAGTAtt |
Disrupted |
N |
0.009 |
| T |
hsa-miR-8084 |
18 |
aaaaaaTAGTATT |
Created |
N |
-0.089 |
|||
| 124988885 | rs200066364 | A | A |
hsa-miR-5003-3p |
18 |
aaaaaAAAAGTAt |
Disrupted |
N |
0.009 |
| 124988989 | rs116168950 | A | A |
hsa-miR-486-5p |
9 |
caGTACAGGctgc |
Disrupted |
N |
-0.143 |