SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000090
Gene Symbol: COL3A1
Description: Homo sapiens collagen, type III, alpha 1 (COL3A1), mRNA.
Gene Location: chr2(+):189839098-189877472
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr2:g.189011982T>- ICGC_ssm_v3_99839 HCC34T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.189012059C>T COSN14988931 SM-4AX85 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-128 tgataacaaCACTGTGtta
 13
 UCACAGUG m7b (m7b->m6c) -0.241000 no TS 1.840000
hsa-miR-144-3p tgataacaATACTGTgtta
 0 UACAGUAU m7b Created no TS -0.158000 -0.360000
hsa-miR-16-1-3p tgataacAATACTGtgtta
 0 CCAGUAUU m7b Created no TS -0.105000 -0.090000
hsa-miR-3681-3p tgataacaaCACTGTGTta
 13
 ACACAGUG m8a (m8a->m7b) -0.260000 no TS 1.800000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.189012241T>A COSN4800243 tumor_4104893 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3163 tgaaaaaaATTTTATAcgt
 2
 UAUAAAAU m8a Disrupted 0.044000 no TS No effect
hsa-miR-4282 tgaaaaAAATTTTAtacgt
 2
 UAAAAUUU m8a Disrupted 0.037000 no TS 0.404000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.189012391T>C COSN6159963 RK199_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-583 aggtgctCCTCTTTtttct
 0 CAAAGAGG m7b Disrupted -0.179000 -0.047000 0.860000
hsa-miR-939 aggtGCTCCCCttttttct
 0 UGGGGAGC m7b Created no TS -0.289000 -2.120000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.189012687G>A COSN8275881 PCSI_0048_Pa_P_526 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-let-7a-3p agcTTGTATAtggttgttg
 0 CUAUACAA m7b (m6b->m7b) no TS -0.058000 -0.360000
hsa-let-7b-3p agcTTGTATAtggttgttg
 0 CUAUACAA m7b (m6b->m7b) no TS -0.058000 -0.850000
hsa-let-7f-1-3p agcTTGTATAtggttgttg
 0 CUAUACAA m7b (m6b->m7b) no TS -0.058000 -0.630000
hsa-miR-300 agCTTGTATAtggttgttg
 15
 UAUACAAG m8a (m7a->m8a) -0.103000 -0.226000 -0.500000
hsa-miR-381 agCTTGTATAtggttgttg
 15
 UAUACAAG m8a (m7a->m8a) -0.103000 -0.226000 -0.510000

Mutation Mutation ID Sample Name Cancer Type
chr2:g.189012736T>C 9_67640 CRC-7-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3689a-5p aaaATATCACAttaaaatt
 20
 UGUGAUAU m8a Created no TS -0.42 -1.58
hsa-miR-3689b-5p aaaATATCACAttaaaatt
 20
 UGUGAUAU m8a Created no TS -0.42 -1.58
hsa-miR-3689e aaaATATCACAttaaaatt
 20
 UGUGAUAU m8a Created no TS -0.42 -1.58
hsa-miR-3689f aaaATATCACAttaaaatt
 20
 UGUGAUAU m8a Created no TS -0.42 -1.81
hsa-miR-4517 aaaataTCATATTaaaatt
 7
 AAAUAUGA m7b Disrupted -0.279 no TS 1.13
hsa-miR-5583-3p aaaatatCATATTaaaatt
 7
 GAAUAUGG m6b Disrupted -0.108 no TS -1.49
hsa-miR-889 aaaatatcATATTAAaatt
 7
 UUAAUAUC m7a Disrupted -0.042 no TS 0.18

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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