SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_005602
Gene Symbol: CLDN11
Description: Homo sapiens claudin 11 (CLDN11), transcript variant 2, mRNA.
Gene Location: chr3(+):170136652-170152479
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr3:g.170432797G>T COSN6753128 RK053_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1285-3p tagatgctgTGCCCAGggc
 2
 UCUGGGCA m7b (m6c->m7b) -0.617000 -0.734000 No effect
hsa-miR-296-5p tagatgctGGGCCCagggc
 2
 AGGGCCCC m6b Disrupted -0.186000 no TS 0.070000
hsa-miR-3187-5p tagatgctgTGCCCAGGgc
 2
 CCUGGGCA m8a (m7b->m8a) -0.596000 -0.704000 No effect
hsa-miR-338-3p tagATGCTGGgcccagggc
 5
 UCCAGCAU m7b (m7b->m6b) -0.073000 no TS -0.070000
hsa-miR-5189 tagatgctgTGCCCAGggc
 2
 UCUGGGCA m7b (m6c->m7b) -0.615000 -0.732000 -3.270000
hsa-miR-612 tagatgctgTGCCCAGggc
 2
 GCUGGGCA m7b (m6c->m7b) -0.670000 -0.815000 -2.030000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.170432984C>G COSN8488671 227_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-191-5p tttttTTCCGTTGgtgttg
 0 CAACGGAA m8a Created no TS -0.255000 -0.030000
hsa-miR-4668-5p tttTTTTCCCTtggtgttg
 0 AGGGAAAA m8a Disrupted -0.142000 no TS 0.060000
hsa-miR-5584-5p ttttTTTCCCTtggtgttg
 0 CAGGGAAA m7b Disrupted -0.185000 -0.032000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.170433087C>T COSN15416683 AOCS-167-16-X [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3145-3p ttttgcAAATATCactgag
 0 AGAUAUUU m7b Created no TS -0.071000 -0.210000
hsa-miR-3689a-5p ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.129000 No effect
hsa-miR-3689b-5p ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.129000 No effect
hsa-miR-3689e ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.129000 No effect
hsa-miR-3689f ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.147000 -0.150000
hsa-miR-557 tttTGCAAACatcactgag
 0 GUUUGCAC m7a (m7a->m6a) -0.001000 -0.001000 No effect
hsa-miR-3145-3p ttttgcAAATATCactgag
 0 AGAUAUUU m7b Created no TS -0.071000 -0.210000
hsa-miR-3689a-5p ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.129000 No effect
hsa-miR-3689b-5p ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.129000 No effect
hsa-miR-3689e ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.129000 No effect
hsa-miR-3689f ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.147000 -0.150000
hsa-miR-557 tttTGCAAACatcactgag
 0 GUUUGCAC m7a (m7a->m6a) -0.001000 -0.001000 No effect
hsa-miR-3145-3p ttttgcAAATATCactgag
 0 AGAUAUUU m7b Created no TS -0.071000 -0.210000
hsa-miR-3689a-5p ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.129000 No effect
hsa-miR-3689b-5p ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.129000 No effect
hsa-miR-3689e ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.129000 No effect
hsa-miR-3689f ttttgcaaATATCACtgag
 0 UGUGAUAU m7b Created no TS -0.147000 -0.150000
hsa-miR-557 tttTGCAAACatcactgag
 0 GUUUGCAC m7a (m7a->m6a) -0.001000 -0.001000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr3:g.170433407T>C ICGC_73FBA398-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4530 cccaaagTGCTGGGattat
 0 CCCAGCAG m7a Created NA NA -7.84
hsa-miR-4733-5p cccaaagtgTTGGGATTat
 0 AAUCCCAA m8a (m8a->m7b) -0.058 no TS 0.01

Mutation Mutation ID Sample Name Cancer Type
chr3:g.170433651->T cosmic_v64_1870281 NA [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1323 tttttAGTTTTGtgatttta
 0 UCAAAACU m7b Created no TS -0.038000 -0.010000
hsa-miR-548o-3p tttttAGTTTTGtgatttta
 0 CCAAAACU m7b Created no TS -0.047000 -0.040000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.170433682T>A COSN9763673 C0089T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-643 catactttTACAAGattga
 2
 ACUUGUAU m6b Created -0.266000 -0.306000 -3.140000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.170433745A>T COSN5040516 HX33T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-362-5p tatgAAGGATatgaaccac
 0 AAUCCUUG m6b Created no TS -0.029000 -2.610000
hsa-miR-5007-3p tatgaaggATATGAaccac
 6
 AUCAUAUG m6b Created 0.056000 0.110000 0.930000
hsa-miR-500b tatgAAGGATatgaaccac
 0 AAUCCUUG m6b Created no TS -0.036000 -0.820000
hsa-miR-501-5p tatgAAGGATatgaaccac
 0 AAUCCUUU m6b Created no TS -0.027000 No effect
hsa-miR-5696 tatgaaggAAATGAaccac
 14
 CUCAUUUA m6b Disrupted 0.095000 no TS 0.060000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.170434255C>T 9_129767 CRC-1-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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