SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_000084
Gene Symbol:	CLCN5
Description:	Homo sapiens chloride channel 5 (CLCN5), transcript variant 3, mRNA.
Gene Location:	chrX(+):49832214-49863892

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chrX:g.50094506A>G			ICGC_sm265117		RK054_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4517	tttggTCATATTTcatagt	5	AAAUAUGA	m8a	Disrupted	0.246	0.118	0.02
hsa-miR-494	tttggtcATGTTTCAtagt	0	UGAAACAU	m8a	Created	0.188	0.358	-0.01

Mutation			Mutation ID		Sample Name		Cancer Type
chrX:g.50095210G>A			ICGC_sm30270		RK007_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4326	aaaAGGAACAagagtctat	0	UGUUCCUC	m7a	(m6a->m7a)	0.024	0.04	No effect

Mutation			Mutation ID		Sample Name		Cancer Type
chrX:g.50095365A>C			ICGC_sm361775		RK086_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-302b-5p	gcaactTTAAAGatcattt	3	ACUUUAAC	m6b	Disrupted	0.29	0.136	0.01
hsa-miR-302d-5p	gcaactTTAAAGatcattt	3	ACUUUAAC	m6b	Disrupted	0.286	0.132	No effect
hsa-miR-3607-3p	gcaacTTTACAGatcattt	0	ACUGUAAA	m7b	Created	0.213	0.376	-0.48
hsa-miR-3686	gcaactTTACAGATcattt	0	AUCUGUAA	m8a	Created	-0.013	0.041	-1.55

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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