SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_000746
Gene Symbol: CHRNA7
Description: Homo sapiens cholinergic receptor, nicotinic, alpha 7 (CHRNA7), transcript variant 1, mRNA.
Gene Location: chr15(+):32322690-32462384
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr15:g.32168959A>G COSN15020419 LP6005409-DNA_A02 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-183-3p ttttctgcAATTCAacttt
1
GUGAAUUA m6b Disrupted 0.013000 0.019000 0.420000
hsa-miR-219-2-3p ttttctgCAATTCaacttt
4
AGAAUUGU m6b Disrupted -0.063000 no TS No effect
hsa-miR-2964a-3p ttttctGCAATTCaacttt
3
AGAAUUGC m7b Disrupted -0.331000 -0.060000 0.290000
hsa-miR-3158-5p tttTCTGCAGttcaacttt
2
CCUGCAGA m7b (m6b->m7b) -0.218000 -0.474000 -2.920000
hsa-miR-3545-3p ttttctgCAGTTCAActtt
0 UUGAACUG m8a Created no TS -0.258000 -7.670000
hsa-miR-4418 ttttCTGCAGTtcaacttt
0 CACUGCAG m7b Created no TS -0.250000 -10.280000
hsa-miR-509-3-5p ttttCTGCAGTtcaacttt
0 UACUGCAG m7b Created no TS -0.231000 -2.940000
hsa-miR-509-5p ttttCTGCAGTtcaacttt
0 UACUGCAG m7b Created no TS -0.231000 -2.370000

Mutation Mutation ID Sample Name Cancer Type
chr15:g.32169132C>A COSN8589784 J30_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-204-5p tcAAAGGGAAgcaggtttc
2
UUCCCUUU m8a (m7a->m8a) -0.043000 -0.134000 -0.280000
hsa-miR-211-5p tcAAAGGGAAgcaggtttc
2
UUCCCUUU m8a (m7a->m8a) -0.052000 -0.145000 -0.280000
hsa-miR-2115-5p tcaaagGGAAGCaggtttc
0 AGCUUCCA m6b Created no TS -0.105000 -12.470000
hsa-miR-3193 tcaaagggACGCAGGtttc
0 UCCUGCGU m7b Disrupted -0.222000 no TS 5.940000
hsa-miR-4755-5p tcaAAGGGAAgcaggtttc
0 UUUCCCUU m7b (m6b->m7b) no TS -0.064000 -0.480000
hsa-miR-5006-3p tcaAAGGGAAgcaggtttc
0 UUUCCCUU m7b (m6b->m7b) no TS -0.083000 -0.030000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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