SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001257387
Gene Symbol: CHEK2
Description: Homo sapiens checkpoint kinase 2 (CHEK2), transcript variant 3, mRNA.
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Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr22:g.28687854C>G COSN8612538 202_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-128 tctttCACTGTGtcatctt
0 UCACAGUG m7b Created no TS -0.262000 -5.350000
hsa-miR-3681-3p tctttCACTGTGTcatctt
0 ACACAGUG m8a Created no TS -0.234000 -7.920000
hsa-miR-425-5p tctttcactGTGTCATctt
0 AAUGACAC m7b (m6b->m7b) no TS -0.205000 -0.690000
hsa-miR-4797-5p tctttcACTCTGTCatctt
0 GACAGAGU m8a Disrupted -0.182000 no TS 4.790000
hsa-miR-5586-3p tcttTCACTCTGtcatctt
0 CAGAGUGA m8a Disrupted -0.240000 no TS 8.220000
hsa-miR-642a-3p tctttcacTGTGTCatctt
0 AGACACAU m6b Created no TS -0.166000 -14.920000
hsa-miR-642b-3p tctttcacTGTGTCatctt
0 AGACACAU m6b Created no TS -0.166000 -14.620000
hsa-miR-759 tctttCACTCTGtcatctt
0 GCAGAGUG m7b Disrupted -0.258000 no TS 5.030000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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