SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_000077
Gene Symbol:	CDKN2A
Description:	Homo sapiens cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) (CDKN2A), transcript variant 1, mRNA.
Gene Location:	chr9(-):21967750-21975132
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Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.21968200G>C			COSN14880215		CHC320T		[liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1203	agaaacCTCCGGaaactta	0	CCCGGAGC	m6b	Created	-0.218000	-0.484000	-0.270000
hsa-miR-4664-3p	agaaacctCCGGAAactta	0	CUUCCGGU	m6b	Created	no TS	-0.248000	-0.010000
hsa-miR-4740-3p	agaaacCTCGGGaaactta	0	GCCCGAGA	m6b	Disrupted	-0.240000	no TS	0.360000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
21968200	rs11515	C	G	hsa-miR-4740-3p	0	aacCTCGGGAaac	Created	N	-0.24
			C	hsa-miR-1180-3p hsa-miR-1203 hsa-miR-4664-3p	0	aacctCCGGAAAc aacCTCCGGAaac aacctCCGGAAAc	Disrupted Disrupted Disrupted	N N N	-0.235 -0.266 -0.248

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