SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001220777
Gene Symbol: CDKN1A
Description: Homo sapiens cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A), transcript variant 1, mRNA.
Gene Location: chr6(+):36644236-36655116
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr6:g.36686315G>T COSN8514252 J30_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1283 aaaacTTTGTAGtcccctc
 0 UCUACAAA m7b Created no TS 0.052000 -3.590000
hsa-miR-3145-5p aaaactTTGGAGTcccctc
 0 AACUCCAA m7b Disrupted -0.323000 -0.283000 0.070000
hsa-miR-3973 aaaACTTTGTagtcccctc
 9
 ACAAAGUA m7a (m6a->m7a) 0.011000 0.011000 No effect
hsa-miR-520d-5p aaaaCTTTGTAGtcccctc
 0 CUACAAAG m8a Created no TS 0.010000 -8.890000
hsa-miR-520g aaaACTTTGTagtcccctc
 9
 ACAAAGUG m7a (m6a->m7a) -0.210000 -0.210000 -1.060000
hsa-miR-520h aaaACTTTGTagtcccctc
 9
 ACAAAGUG m7a (m6a->m7a) -0.210000 -0.210000 -0.910000
hsa-miR-524-5p aaaaCTTTGTAGtcccctc
 0 CUACAAAG m8a Created no TS 0.038000 -3.780000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.36686647C>T COSN8514253 308_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3160-3p gtaccctcTCAGCTCcagg
 9
 AGAGCUGA m7b Disrupted -0.127000 -0.099000 1.510000
hsa-miR-4633-3p gtaccctctTAGCTCCagg
 2
 AGGAGCUA m7b (m6c->m7b) -0.079000 -0.212000 -0.820000
hsa-miR-610 gtaccctcTTAGCTCcagg
 0 UGAGCUAA m7b Created no TS -0.012000 -10.290000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.36687005G>C COSN9781735 AOCS-106-1-1 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-103b gcagtagaGGCTATGgaca
 0 UCAUAGCC m7b Disrupted -0.182000 no TS 1.470000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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