SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_004360 |
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Gene Symbol: | CDH1 |
Description: | Homo sapiens cadherin 1, type 1, E-cadherin (epithelial) (CDH1), mRNA. |
Gene Location: | chr16(+):68771194-68869444 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr16:g.68833862G>A | COSN7269152 | 8031121 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3127-3p |
aaaGAAGGGGAgaagtcag |
3 |
UCCCCUUC | m8a | Disrupted | -0.405000 | no TS |
0.010000 |
|
hsa-miR-4755-5p |
aaagAAGGGAAgaagtcag |
0 | UUUCCCUU | m7b | Created | no TS | -0.093000 |
-0.080000 |
|
hsa-miR-4778-3p |
aaagaaggGAAGAAGtcag |
2 |
UCUUCUUC | m7b | Created | -0.026000 | -0.086000 |
-2.840000 |
|
hsa-miR-5006-3p |
aaagAAGGGAAgaagtcag |
0 | UUUCCCUU | m7b | Created | no TS | -0.102000 | No effect | |
hsa-miR-623 |
aaagAAGGGAagaagtcag |
0 | AUCCCUUG | m6b | Created | no TS | -0.112000 |
-0.450000 |
|
hsa-miR-629-3p |
aaagaagGGGAGAAgtcag |
2 |
GUUCUCCC | m7b | Disrupted | -0.265000 | -0.120000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr16:g.68834125T>A | COSN7269153 | 8062308 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr16:g.68834753C>T | COSN8601916 | J90_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr16:g.68835430C>T | COSN7269154 | 8016470 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-21-3p |
gtgtgGGTGTTGataattg |
0 | CAACACCA | m7a | Created | NA | NA | No effect |
hsa-miR-3065-3p |
gtgtgGGTGCTGAtaattg |
10 |
UCAGCACC | m8a | Disrupted | -0.448000 | no TS |
0.230000 |
hsa-miR-374a-3p |
gtgtgggtgCTGATAAttg |
0 | CUUAUCAG | m7b | (m7b->m6c) | -0.093000 | no TS |
1.410000 |
hsa-miR-421 |
gtgtgggTGTTGATaattg |
1 |
AUCAACAG | m7a | Created | -0.086000 | -0.086000 |
-1.830000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
68833600 | rs1138533 | G | G |
hsa-miR-2355-5p hsa-miR-3679-3p hsa-miR-4446-5p |
2 1 1 |
ttCTGGGGAAaaa ttctGGGGAAAaa ttctgGGGAAAAa |
Disrupted Disrupted Disrupted |
N N N |
-0.488 -0.181 -0.11 |
A |
hsa-miR-3925-3p hsa-miR-515-5p hsa-miR-519e-5p hsa-miR-629-3p hsa-miR-766-3p |
2 2 2 1 2 |
ttCTGGAGAaaaa ttcTGGAGAAaaa ttcTGGAGAAaaa ttctGGAGAAAaa ttCTGGAGAaaaa |
Created Created Created Created Created |
N N N N N |
-0.177 -0.153 -0.147 -0.111 -0.155 |