| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_006035 |
|---|---|
| Gene Symbol: | CDC42BPB |
| Description: | Homo sapiens CDC42 binding protein kinase beta (DMPK-like) (CDC42BPB), mRNA. |
| Gene Location: | chr14(-):103398715-103523742 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr14:g.102933014T>C | COSN1164520 | HX16T | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1207-5p |
gcttctgccCCCTGCCAta |
0 | UGGCAGGG | m8a | (m7a->m8a) | -0.729000 | -0.893000 | No effect |
| hsa-miR-1827 |
gcttCTGCCTCctgccata |
0 | UGAGGCAG | m7b | Disrupted | -0.114000 | no TS |
0.570000 |
| hsa-miR-1909-3p |
gcttctgcCCCCTGCcata |
1 |
CGCAGGGG | m7b | Created | -0.216000 | -0.347000 | No effect |
| hsa-miR-3612 |
gcttcTGCCTCCTgccata |
4 |
AGGAGGCA | m8a | Disrupted | -0.253000 | -0.150000 |
0.900000 |
| hsa-miR-4459 |
gcttctgCCTCCTGccata |
0 | CCAGGAGG | m7b | Disrupted | -0.146000 | -0.073000 |
4.680000 |
| hsa-miR-4695-5p |
gcttctGCCTCCTGccata |
0 | CAGGAGGC | m8a | Disrupted | -0.127000 | no TS |
0.350000 |
| hsa-miR-4722-5p |
gcttctgcCTCCTGCCata |
7 |
GGCAGGAG | m8a | Disrupted | -0.371000 | -0.278000 |
0.080000 |
| hsa-miR-4763-3p |
gcttctgccCCCTGCCata |
0 | AGGCAGGG | m7b | (m6b->m7b) | -0.814000 | -0.988000 | No effect |
| hsa-miR-486-3p |
gcttCTGCCCCctgccata |
0 | CGGGGCAG | m7b | Created | -0.075000 | -0.235000 |
-0.130000 |
| hsa-miR-650 |
gcttcTGCCTCCTgccata |
4 |
AGGAGGCA | m8a | Disrupted | -0.254000 | -0.160000 |
0.220000 |
| hsa-miR-1207-5p |
gcttctgccCCCTGCCAta |
0 | UGGCAGGG | m8a | (m7a->m8a) | -0.729000 | -0.893000 | No effect |
| hsa-miR-1827 |
gcttCTGCCTCctgccata |
0 | UGAGGCAG | m7b | Disrupted | -0.114000 | no TS |
0.570000 |
| hsa-miR-1909-3p |
gcttctgcCCCCTGCcata |
1 |
CGCAGGGG | m7b | Created | -0.216000 | -0.347000 | No effect |
| hsa-miR-3612 |
gcttcTGCCTCCTgccata |
4 |
AGGAGGCA | m8a | Disrupted | -0.253000 | -0.150000 |
0.900000 |
| hsa-miR-4459 |
gcttctgCCTCCTGccata |
0 | CCAGGAGG | m7b | Disrupted | -0.146000 | -0.073000 |
4.680000 |
| hsa-miR-4695-5p |
gcttctGCCTCCTGccata |
0 | CAGGAGGC | m8a | Disrupted | -0.127000 | no TS |
0.350000 |
| hsa-miR-4722-5p |
gcttctgcCTCCTGCCata |
7 |
GGCAGGAG | m8a | Disrupted | -0.371000 | -0.278000 |
0.080000 |
| hsa-miR-4763-3p |
gcttctgccCCCTGCCata |
0 | AGGCAGGG | m7b | (m6b->m7b) | -0.814000 | -0.988000 | No effect |
| hsa-miR-486-3p |
gcttCTGCCCCctgccata |
0 | CGGGGCAG | m7b | Created | -0.075000 | -0.235000 |
-0.130000 |
| hsa-miR-650 |
gcttcTGCCTCCTgccata |
4 |
AGGAGGCA | m8a | Disrupted | -0.254000 | -0.160000 |
0.220000 |
| hsa-miR-1207-5p |
gcttctgccCCCTGCCAta |
0 | UGGCAGGG | m8a | (m7a->m8a) | -0.729 | -0.893 | No effect |
| hsa-miR-1827 |
gcttCTGCCTCctgccata |
0 | UGAGGCAG | m7b | Disrupted | -0.114 | no TS |
0.57 |
| hsa-miR-1909-3p |
gcttctgcCCCCTGCcata |
0 | CGCAGGGG | m7b | Created | -0.216 | -0.347 | No effect |
| hsa-miR-3612 |
gcttcTGCCTCCTgccata |
0 | AGGAGGCA | m8a | Disrupted | -0.253 | -0.15 |
0.9 |
| hsa-miR-4459 |
gcttctgCCTCCTGccata |
0 | CCAGGAGG | m7b | Disrupted | -0.146 | -0.073 |
4.68 |
| hsa-miR-4695-5p |
gcttctGCCTCCTGccata |
0 | CAGGAGGC | m8a | Disrupted | -0.127 | no TS |
0.35 |
| hsa-miR-4722-5p |
gcttctgcCTCCTGCCata |
0 | GGCAGGAG | m8a | Disrupted | -0.371 | -0.278 |
0.08 |
| hsa-miR-4763-3p |
gcttctgccCCCTGCCata |
0 | AGGCAGGG | m7b | (m6b->m7b) | -0.814 | -0.988 | No effect |
| hsa-miR-486-3p |
gcttCTGCCCCctgccata |
0 | CGGGGCAG | m7b | Created | -0.075 | -0.235 |
-0.13 |
| hsa-miR-650 |
gcttcTGCCTCCTgccata |
0 | AGGAGGCA | m8a | Disrupted | -0.254 | -0.16 |
0.22 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 102932865 | rs35675176 | C | C |
hsa-miR-1286 hsa-miR-486-3p hsa-miR-6721-5p |
2 2 2 |
GTCCTGCccccgc gtcCTGCCCCcgc gtCCTGCCCccgc |
Disrupted Disrupted Disrupted |
N N N |
-0.057 -0.075 -0.077 |
| T |
hsa-miR-4700-3p hsa-miR-4706 hsa-miR-4749-5p |
2 3 3 |
GTCCTGTccccgc gtcctgTCCCCGC gtcctgTCCCCGC |
Created Created Created |
N N N |
-0.01 -0.22 -0.198 |
|||
| 102932897 | rs35903000 | C | C |
hsa-miR-1908-5p hsa-miR-3141 hsa-miR-3180 hsa-miR-3180-3p hsa-miR-3196 hsa-miR-663a hsa-miR-6787-5p hsa-miR-6816-5p hsa-miR-744-5p |
1 1 0 0 0 1 1 0 0 |
ccgCCCCGCCctg ccgccCCGCCCTg CCGCCCCgccctg CCGCCCCgccctg CCGCCCCgccctg ccgCCCCGCCctg ccgCCCCGCCctg CCGCCCCgccctg ccGCCCCGCcctg |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N |
-0.082 0.031 -0.129 -0.129 -0.138 -0.101 -0.091 -0.138 -0.133 |
| T |
hsa-miR-1207-5p hsa-miR-4436b-3p hsa-miR-4632-5p hsa-miR-4763-3p hsa-miR-6132 hsa-miR-6721-5p hsa-miR-6735-5p hsa-miR-6836-5p hsa-miR-6879-5p hsa-miR-7843-5p |
1 1 1 1 0 1 1 0 1 1 |
ccgCCCTGCCctg ccgccCTGCCCTg ccgccCTGCCCTg ccgCCCTGCCctg ccGCCCTGCcctg ccgcCCTGCCCtg ccgccCTGCCCTg ccGCCCTGCcctg ccgccCTGCCCTg ccgccCTGCCCTg |
Created Created Created Created Created Created Created Created Created Created |
N N N N N N N N N N |
-0.096 0.003 -0.025 -0.086 -0.098 -0.037 0.022 -0.098 -0.034 0.04 |
|||
| 102933415 | rs141834100 | T | T |
hsa-miR-1207-5p hsa-miR-3918 hsa-miR-4736 hsa-miR-4763-3p hsa-miR-6132 hsa-miR-6836-5p hsa-miR-7150 hsa-miR-7160-3p |
4 4 4 4 4 4 4 4 |
gggCCCTGCCAac gGGCCCTGccaac gggcCCTGCCAac gggCCCTGCCAac ggGCCCTGCcaac ggGCCCTGCcaac gggcCCTGCCAAc GGGCCCTgccaac |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N |
-0.308 -0.172 -0.122 -0.339 -0.164 -0.164 -0.245 -0.188 |
| G |
hsa-miR-4743-5p |
4 |
gggcCCGGCCAac |
Created |
N |
-0.232 |
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| 102933666 | rs35064888 | A | A |
hsa-miR-3135b hsa-miR-3612 hsa-miR-4443 hsa-miR-650 |
3 4 4 4 |
gcCTCCAGCgtca GCCTCCAgcgtca GCCTCCAgcgtca GCCTCCAgcgtca |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.126 -0.15 -0.114 -0.16 |
| G |
hsa-miR-6786-3p |
1 |
gcctccGGCGTCA |
Created |
N |
-0.23 |