SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_080617
Gene Symbol:	CBLN4
Description:	Homo sapiens cerebellin 4 precursor (CBLN4), mRNA.
Gene Location:	chr20(-):54572495-54580012
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr20:g.55997787C>T			COSN7098232		8061178		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4257	gctccCCTCTGagggaaat	0	CCAGAGGU	m6b	Created	no TS	-0.096000	-8.140000
hsa-miR-4655-3p	gctcccctcCGAGGGaaat	2	ACCCUCGU	m6b	Disrupted	-0.240000	no TS	9.460000

Mutation			Mutation ID		Sample Name		Cancer Type
chr20:g.55997836C>A			COSN8611137		J30_T		[lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1225-5p	gttgctTACCCAaaatcta	2	GUGGGUAC	m6b	Disrupted	-0.140000	no TS	0.880000
hsa-miR-2113	gttgcttaCACAAAatcta	0	AUUUGUGC	m6b	Created	no TS	-0.034000	-1.050000
hsa-miR-5010-3p	gttgcttACACAAAAtcta	0	UUUUGUGU	m8a	Created	no TS	-0.176000	-0.050000
hsa-miR-555	gttgCTTACCCaaaatcta	2	AGGGUAAG	m7b	Disrupted	-0.353000	no TS	0.580000
hsa-miR-599	gttgcttACACAAaatcta	0	GUUGUGUC	m6b	Created	no TS	-0.051000	-0.230000

Mutation			Mutation ID		Sample Name		Cancer Type
chr20:g.55997851G>T			COSN7098233		8014825		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-2681-5p	tctgacaaGTAAAAagttg	2	GUUUUACC	m6b	Created	0.006000	0.020000	No effect
hsa-miR-502-5p	tctgaCAAGGAaaaagttg	0	AUCCUUGC	m6b	Disrupted	-0.095000	no TS	1.050000

Mutation			Mutation ID		Sample Name		Cancer Type
chr20:g.55997943C>A			COSN195678		PD4198a		[NS][NS][NS][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1179	aaaaGAATGCTTcatagtt	7	AAGCAUUC	m8a	Disrupted	-0.220000	no TS	0.050000
hsa-miR-15b-3p	aaaagaATGATTCatagtt	0	CGAAUCAU	m7b	Created	no TS	-0.223000	-1.460000
hsa-miR-382-3p	aaaaGAATGATTcatagtt	0	AAUCAUUC	m8a	Created	no TS	-0.115000	-0.600000
hsa-miR-1179	aaaaGAATGCTTcatagtt	0	AAGCAUUC	m8a	Disrupted	-0.22	no TS	0.05
hsa-miR-15b-3p	aaaagaATGATTCatagtt	0	CGAAUCAU	m7b	Created	no TS	-0.223	-1.46
hsa-miR-382-3p	aaaaGAATGATTcatagtt	0	AAUCAUUC	m8a	Created	no TS	-0.115	-0.6

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
55997946	rs11483268	-	-	hsa-miR-1179	7	aaaaGAATGCTtc	Unknown	N	-0.22
			A

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