SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_032996
Gene Symbol:	CASP9
Description:	Homo sapiens caspase 9, apoptosis-related cysteine peptidase (CASP9), transcript variant alpha, mRNA.
Gene Location:	chr1(-):15818768-15851285
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.15492437G>T			COSN1408142		RK061_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4668-3p	gtctgtagGGATTTTtggc	3	GAAAAUCC	m7b	Disrupted	-0.001000	no TS	No effect
hsa-miR-548c-3p	gtctgtaggGATTTTTGgc	3	CAAAAAUC	m8a	(m8a->m7a)	0.103000	no TS	No effect
hsa-miR-605	gtctgtaGGGATTTttggc	3	UAAAUCCC	m7b	Disrupted	-0.162000	no TS	-0.510000
hsa-miR-4668-3p	gtctgtagGGATTTTtggc	3	GAAAAUCC	m7b	Disrupted	-0.001000	no TS	No effect
hsa-miR-548c-3p	gtctgtaggGATTTTTGgc	3	CAAAAAUC	m8a	(m8a->m7a)	0.103000	no TS	No effect
hsa-miR-605	gtctgtaGGGATTTttggc	3	UAAAUCCC	m7b	Disrupted	-0.162000	no TS	-0.510000

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.15492438G>A			COSN1408144		RK061_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-216b	ggtctgtAGAGATTTttgg	0	AAAUCUCU	m8a	Created	no TS	-0.131000	-1.940000
hsa-miR-3675-3p	ggtctgTAGAGATttttgg	0	CAUCUCUA	m7b	Created	no TS	-0.105000	-1.950000
hsa-miR-4668-3p	ggtctgtagGGATTTTtgg	3	GAAAAUCC	m7b	(m7b->m6b)	-0.001000	no TS	No effect
hsa-miR-4684-5p	ggtctGTAGAGAtttttgg	0	CUCUCUAC	m7b	Created	no TS	-0.171000	-1.910000
hsa-miR-605	ggtctgtaGGGATTTttgg	3	UAAAUCCC	m7b	Disrupted	-0.162000	no TS	-0.510000
hsa-miR-216b	ggtctgtAGAGATTTttgg	0	AAAUCUCU	m8a	Created	no TS	-0.131000	-1.940000
hsa-miR-3675-3p	ggtctgTAGAGATttttgg	0	CAUCUCUA	m7b	Created	no TS	-0.105000	-1.950000
hsa-miR-4668-3p	ggtctgtagGGATTTTtgg	3	GAAAAUCC	m7b	(m7b->m6b)	-0.001000	no TS	No effect
hsa-miR-4684-5p	ggtctGTAGAGAtttttgg	0	CUCUCUAC	m7b	Created	no TS	-0.171000	-1.910000
hsa-miR-605	ggtctgtaGGGATTTttgg	3	UAAAUCCC	m7b	Disrupted	-0.162000	no TS	-0.510000

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.15492931C>A			COSN8644654		AOCS-116-1-3		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1914-3p	ccagggCCCCTCaccctgc	5	GGAGGGGU	m6b	Disrupted	0.000000	no TS	No effect
hsa-miR-3184-5p	ccaggGCCCCTCAccctgc	4	UGAGGGGC	m8a	Disrupted	0.000000	no TS	No effect
hsa-miR-423-5p	ccaggGCCCCTCAccctgc	4	UGAGGGGC	m8a	Disrupted	0.000000	no TS	No effect
hsa-miR-4710	ccagggccCCTCACCCtgc	5	GGGUGAGG	m8a	Disrupted	0.000000	no TS	No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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