SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_032976
Gene Symbol:	CASP10
Description:	Homo sapiens caspase 10, apoptosis-related cysteine peptidase (CASP10), transcript variant 6, mRNA.
Gene Location:	chr2(+):202047620-202086383
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Browse Pathways

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.201209131G>A			ICGC_1307965		TCGA-D1-A103-01A-11D-A10M-09		UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.201209140A>G			ICGC_1307967		TCGA-BS-A0UV-01A-11D-A10B-09		UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-136-5p	gaaagtggaAATGGAGatg	0	ACUCCAUU	m7b	(m7b->m6c)	-0.294	-0.11	No effect
hsa-miR-3692-3p	gaaaGTGGAAatggagatg	0	GUUCCACA	m6b	Disrupted	-0.116	no TS	0.01

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.201209270C>T			ICGC_1307968		TCGA-D1-A16Y-01A-31D-A12J-09		UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-150-5p	attcccatTTGGGAGAtca	0	UCUCCCAA	m8a	Created	-0.114	-0.406	0.07
hsa-miR-186-3p	attcccaTTTGGGagatca	0	GCCCAAAG	m6b	Created	no TS	-0.041	No effect
hsa-miR-2116-3p	attcccattTGGGAGatca	0	CCUCCCAU	m6b	Created	-0.334	-0.48	0.36
hsa-miR-4713-5p	attcccattTGGGAGAtca	0	UUCUCCCA	m7b	(m6c->m7b)	-0.216	-0.42	0.01
hsa-miR-532-3p	attcccattTGGGAGatca	0	CCUCCCAC	m6b	Created	-0.124	-0.255	0.04

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.201219002A>G			ICGC_97B08466-2A78-11E2-8335-12FD496BB9B8		CPCG_0102_Pr_P_P2		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation			Mutation ID		Sample Name		Cancer Type
chr2:g.201219174A>G			ICGC_70B80C80-2A78-11E2-96E7-04FD496BB9B8		CPCG_0102_Pr_P_P1		ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1976	gaggctgagGCAGGAGaat	0	CCUCCUGC	m7b	(m6c->m7b)	0.046	-0.001	-0.24
hsa-miR-3120-5p	gaggctgAGACAGGagaat	0	CCUGUCUG	m7a	Disrupted	0.039	0.039	0.01
hsa-miR-4421	gaggctgAGACAGGagaat	0	ACCUGUCU	m7b	Disrupted	0.024	-0.038	No effect
hsa-miR-4722-3p	gaggctgaGGCAGGagaat	0	ACCUGCCA	m6b	Created	-0.03	-0.044	-0.01
hsa-miR-5699	gaggctgAGACAGGAgaat	0	UCCUGUCU	m8a	Disrupted	0.051	-0.001	0.1

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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