SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001206524
Gene Symbol: CASP10
Description: Homo sapiens caspase 10, apoptosis-related cysteine peptidase (CASP10), transcript variant 6, mRNA.
Gene Location: chr2(+):202047620-202086383
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.201218606G>T COSN9304062 AOCS-143-1-0 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1263 tggcctgGGTACCAggtgc
 0 AUGGUACC m7b Created no TS -0.068000 -0.160000
hsa-miR-1295b-5p tggcCTGGGTaccaggtgc
 0 CACCCAGA m6b Created no TS -0.050000 -0.010000
hsa-miR-1915-3p tggCCTGGGGaccaggtgc
 0 CCCCAGGG m7a (m7a->m6a) NA NA No effect
hsa-miR-2355-5p tggcCTGGGGAccaggtgc
 2
 AUCCCCAG m7b Disrupted -0.003000 0.010000 No effect
hsa-miR-4281 tggcctgGGGACCaggtgc
 3
 GGGUCCCG m6b Disrupted -0.295000 -0.172000 No effect
hsa-miR-4482-5p tggcCTGGGTaccaggtgc
 2
 AACCCAGU m6b Created -0.044000 -0.094000 No effect
hsa-miR-4726-3p tggCCTGGGTaccaggtgc
 1
 ACCCAGGU m7a (m6a->m7a) -0.079000 -0.079000 No effect


Mutation Mutation ID Sample Name Cancer Type
chr2:g.201219002A>G ICGC_97B08466-2A78-11E2-8335-12FD496BB9B8 CPCG_0102_Pr_P_P2 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.201219028G>A COSN6932551 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-384 cagtactCTAGGAAgccaa
 0 AUUCCUAG m7b Created no TS 0.064000 No effect
hsa-miR-516a-3p cagtactctAGGAAGCcaa
 0 UGCUUCCU m7b (m6c->m7b) no TS -0.028000 -0.380000
hsa-miR-516b-3p cagtactctAGGAAGCcaa
 0 UGCUUCCU m7b (m6c->m7b) no TS -0.028000 -0.380000
hsa-miR-5571-3p cagtactCTAGGAagccaa
 0 GUCCUAGG m6b Created no TS 0.039000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr2:g.201219174A>G ICGC_70B80C80-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1976 gaggctgagGCAGGAGaat
 0 CCUCCUGC m7b (m6c->m7b) 0.039 -0.018 -0.24
hsa-miR-3120-5p gaggctgAGACAGGagaat
 0 CCUGUCUG m7a Disrupted -0.104 -0.104 0.01
hsa-miR-4421 gaggctgAGACAGGagaat
 1
 ACCUGUCU m7b Disrupted -0.043 -0.087 No effect
hsa-miR-4722-3p gaggctgaGGCAGGagaat
 0 ACCUGCCA m6b Created -0.03 -0.051 -0.01
hsa-miR-5699 gaggctgAGACAGGAgaat
 1
 UCCUGUCU m8a Disrupted -0.016 -0.05 0.11

Mutation Mutation ID Sample Name Cancer Type
chr2:g.201219927G>T COSN5494587 RK101_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-3p gaatgcCTTTGGGCgtgga
 0 GCCCAAAG m8a Created no TS 0.106000 -1.210000
hsa-miR-3910 gaATGCCTTTgggcgtgga
 2
 AAAGGCAU m8a (m7a->m8a) -0.148000 -0.176000 No effect
hsa-miR-548an gaaTGCCTTTgggcgtgga
 0 AAAAGGCA m7b (m6b->m7b) -0.156000 -0.076000 -0.040000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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