SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_001257119
Gene Symbol: CASP1
Description: Homo sapiens caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (CASP1), transcript variant beta, mRNA.
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Somatic mutations that impact miRNA target sites




Mutation Mutation ID Sample Name Cancer Type
chr11:g.105025563A>G COSN5892586 RK175_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.105025997T>A COSN10076963 C0058T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4742-3p accagtaagAATACAGctg
0 UCUGUAUU m7b (m6b->m7b) -0.072000 -0.163000 -0.760000
hsa-miR-550b-3p accAGTAAGAatacagctg
0 UCUUACUC m7a (m6b->m7a) no TS -0.098000 No effect
hsa-miR-630 accagtaAGAATACagctg
0 AGUAUUCU m7b Created no TS -0.241000 -0.080000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.105026230G>T COSN1125709 HCC34T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4722-3p atgtctgtgGGCAGGTaca
0 ACCUGCCA m7a (m7a->m6a) NA NA 1.160000
hsa-miR-4722-3p atgtctgtgGGCAGGTaca
0 ACCUGCCA m7a (m7a->m6a) NA NA 1.160000
hsa-miR-4722-3p atgtctgtgGGCAGGTaca
0 ACCUGCCA m7a (m7a->m6a) NA NA 1.160000
hsa-miR-4722-3p atgtctgtgGGCAGGTaca
0 ACCUGCCA m7a (m7a->m6a) NA NA 1.16

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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