SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_000068
Gene Symbol: CACNA1A
Description: Homo sapiens calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (CACNA1A), transcript variant 1, mRNA.
Gene Location: chr19(-):13317255-13617274
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr19:g.13206549C>A COSN5849424 HCC17T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-5p attcctttgATTCTTTttt
0 CAAAGAAU m7b (m6b->m7b) no TS -0.023000 -3.220000
hsa-miR-186-5p attcctttgATTCTTTttt
0 CAAAGAAU m7b (m6b->m7b) no TS -0.023000 -3.220000

Mutation Mutation ID Sample Name Cancer Type
chr19:g.13206685A>T 12_80 NA [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-126-5p ttaaaaaaaTAATAATaac
0 CAUUAUUA m7b (m7b->m6b) -0.159 -0.159 No effect
hsa-miR-4795-3p ttaaaaaAATAATAataac
0 AUAUUAUU m7b Disrupted -0.272 -0.272 No effect

Mutation Mutation ID Sample Name Cancer Type
chr19:g.13206685T>A COSN1211091 HX5T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-126-5p ttaaaaaaaTAATAATaac
0 CAUUAUUA m7b (m7b->m6b) -0.159000 -0.004000 2.080000
hsa-miR-4795-3p ttaaaaaAATAATAataac
0 AUAUUAUU m7b Disrupted -0.273000 -0.129000 1.860000
hsa-miR-126-5p ttaaaaaaaTAATAATaac
0 CAUUAUUA m7b (m7b->m6b) -0.159000 -0.004000 2.080000
hsa-miR-4795-3p ttaaaaaAATAATAataac
0 AUAUUAUU m7b Disrupted -0.273000 -0.129000 1.860000


Mutation Mutation ID Sample Name Cancer Type
chr19:g.13206933G>A COSN1211092 HCC92T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr19:g.13207813T>C ICGC_ssm_v3_113547 HCC49T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1225-5p cctcggagGTACCCAggcc
0 GUGGGUAC m7b Disrupted -0.056 no TS 0.07

Mutation Mutation ID Sample Name Cancer Type
chr19:g.13207863A>C ICGC_ssm_v3_30629 HCC105T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-370 agcagcagCAGCAGGCggt
0 GCCUGCUG m8a Disrupted -0.054 no TS 0.35

Mutation Mutation ID Sample Name Cancer Type
chr19:g.13207864C>G ICGC_ssm_v3_30630 HCC105T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1976 cagcaGCAGGAGcaggcgg
0 CCUCCUGC m7b Created no TS -0.132 -3.35
hsa-miR-370 cagcagcagCAGCAGGCgg
0 GCCUGCUG m8a (m8a->m7a) -0.054 -0.23 -7.08
hsa-miR-4268 cagcagcAGGAGCaggcgg
0 GGCUCCUC m6b Created 0.028 -0.043 No effect
hsa-miR-4448 cagcagcAGGAGCaggcgg
0 GGCUCCUU m6b Created no TS -0.078 No effect

Mutation Mutation ID Sample Name Cancer Type
chr19:g.13207997G>A ICGC_1435208 TCGA-DI-A0WH-01A-12D-A12J-09 UterineCorpusEndometrioidCarcinoma(TCGA,US)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3648 cagcactCCGCGGCggggc
0 AGCCGCGG m7b Disrupted -0.309 no TS 0.2

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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