SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
	Home	Search	Help	Download

Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_016366
Gene Symbol:	CABP2
Description:	Homo sapiens calcium binding protein 2 (CABP2), mRNA.
Gene Location:	chr11(-):67286417-67290899
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr11:g.67519040C>T			COSN8584578		3844_T		[lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3154	ggggaCCCTTCTttcctcc	0	CAGAAGGG	m7b	Created	no TS	-0.140000	-0.020000
hsa-miR-3173-3p	ggggacCCTCCTTTcctcc	1	AAAGGAGG	m8a	Disrupted	-0.085000	no TS	2.440000
hsa-miR-4779	ggggaCCCTCCTttcctcc	2	UAGGAGGG	m7b	Disrupted	-0.181000	no TS	-0.020000

Mutation			Mutation ID		Sample Name		Cancer Type
chr11:g.67519085C>A			COSN8688422		AOCS-155-3-5		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-143-5p	agcctCTGCACaccagcat	0	GGUGCAGU	m6b	Created	no TS	-0.098000	-8.540000
hsa-miR-3650	agcctctgCACACCagcat	0	AGGUGUGU	m6b	Created	no TS	-0.141000	-10.890000
hsa-miR-3678-3p	agcCTCTGCAcaccagcat	0	CUGCAGAG	m7b	(m6c->m7b)	no TS	-0.116000	-5.410000
hsa-miR-4417	agcctctGCCCACCagcat	0	GGUGGGCU	m7a	Disrupted	NA	NA	-0.370000
hsa-miR-4456	agcctctgcCCACCAGcat	3	CCUGGUGG	m7b	(m7b->m6b)	-0.158000	no TS	0.010000
hsa-miR-541-3p	agcctctGCCCACCAgcat	0	UGGUGGGC	m8a	Disrupted	-0.624000	-0.157000	1.660000
hsa-miR-654-5p	agcctctGCCCACCAgcat	0	UGGUGGGC	m8a	Disrupted	-0.628000	-0.161000	0.420000
hsa-miR-92a-2-5p	agcctctgCCCACCagcat	0	GGGUGGGG	m6b	Disrupted	-0.544000	-0.394000	0.080000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
67518986	rs201870048	C	C	hsa-miR-323a-5p hsa-miR-541-3p hsa-miR-654-5p hsa-miR-6769a-5p hsa-miR-6769b-5p hsa-miR-876-3p hsa-miR-92a-2-5p	1 3 3 3 3 1 3	ccccACCACCAct cCCCACCAccact cCCCACCAccact cCCCACCAccact cCCCACCAccact ccccACCACCAct CCCCACCAccact	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N N	-0.135 -0.157 -0.161 -0.164 -0.164 -0.145 -0.394
			A	hsa-miR-1273g-5p hsa-miR-140-5p hsa-miR-3151-5p hsa-miR-323b-5p hsa-miR-410-5p hsa-miR-4265 hsa-miR-4296 hsa-miR-4322 hsa-miR-4447 hsa-miR-4472 hsa-miR-491-5p hsa-miR-494-5p hsa-miR-6742-5p hsa-miR-6759-5p hsa-miR-6796-5p	1 1 3 1 1 3 3 3 3 3 3 1 3 3 3	ccccaCAACCACt ccccacAACCACT CCCCACAaccact ccccACAACCAct ccccACAACCAct cCCCACAAccact cCCCACAAccact cCCCACAAccact CCCCACAaccact CCCCACAaccact CCCCACAaccact ccccACAACCAct CCCCACAaccact cCCCACAAccact CCCCACAAccact	Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created	N N N N N N N N N N N N N N N	-0.178 -0.1 -0.181 -0.126 -0.116 -0.13 -0.144 -0.137 -0.233 -0.233 -0.173 -0.109 -0.188 -0.145 -0.382

Genome Browser