SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_144980
Gene Symbol: C6orf118
Description: Homo sapiens chromosome 6 open reading frame 118 (C6orf118), mRNA.
Gene Location: chr6(-):165693152-165723111
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr6:g.165279786A>G COSN1328586 HCC138T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3124-3p ctttGGAAAGTacttttga
 0 ACUUUCCU m7a Created NA NA -3.780000
hsa-miR-548av-5p ctttggaaaGTACTTTTga
 0 AAAAGUAC m8a (m7a->m8a) no TS -0.166000 -2.680000
hsa-miR-548k ctttggaaaGTACTTTTga
 0 AAAAGUAC m8a (m7a->m8a) no TS -0.166000 -1.920000
hsa-miR-548l ctttggaaaATACTTTTga
 4
 AAAAGUAU m8a (m8a->m7a) -0.142000 no TS 0.430000
hsa-miR-3124-3p ctttGGAAAGTacttttga
 0 ACUUUCCU m7a Created NA NA -3.78
hsa-miR-548av-5p ctttggaaaGTACTTTTga
 0 AAAAGUAC m8a (m7a->m8a) no TS -0.166 -2.68
hsa-miR-548k ctttggaaaGTACTTTTga
 0 AAAAGUAC m8a (m7a->m8a) no TS -0.166 -6.44
hsa-miR-548l ctttggaaaATACTTTTga
 0 AAAAGUAU m8a (m8a->m7a) -0.142 no TS 0.43

Mutation Mutation ID Sample Name Cancer Type
chr6:g.165280004T>C COSN167933 GC8_T [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-187-5p ccatgtaTGTAGCatggat
 2
 GGCUACAA m6b Disrupted -0.167000 no TS 6.400000
hsa-miR-221-3p ccatgtATGTAGCatggat
 2
 AGCUACAU m7b Disrupted -0.387000 no TS 9.550000
hsa-miR-222-3p ccatgtATGTAGCatggat
 2
 AGCUACAU m7b Disrupted -0.377000 no TS 11.010000
hsa-miR-548v ccatgtaTGTAGCatggat
 2
 AGCUACAG m6b Disrupted -0.154000 no TS 2.000000
hsa-miR-5689 ccaTGTATGCagcatggat
 0 AGCAUACA m7b (m6c->m7b) no TS -0.390000 -1.780000
hsa-miR-187-5p ccatgtaTGTAGCatggat
 0 GGCUACAA m6b Disrupted -0.167 no TS 6.4
hsa-miR-221-3p ccatgtATGTAGCatggat
 0 AGCUACAU m7b Disrupted -0.387 no TS 9.55
hsa-miR-222-3p ccatgtATGTAGCatggat
 0 AGCUACAU m7b Disrupted -0.377 no TS 11.01
hsa-miR-548v ccatgtaTGTAGCatggat
 0 AGCUACAG m6b Disrupted -0.154 no TS 2
hsa-miR-5689 ccaTGTATGCagcatggat
 0 AGCAUACA m7b (m6c->m7b) no TS -0.39 -1.78

Mutation Mutation ID Sample Name Cancer Type
chr6:g.165280010T>A COSN6312863 RK207_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4802-3p taactTCCATGTAtgtagc
 2
 UACAUGGA m8a Disrupted -0.390000 no TS 7.020000
hsa-miR-890 taactTCCAAGTAtgtagc
 0 UACUUGGA m8a Created no TS -0.376000 -6.590000

Mutation Mutation ID Sample Name Cancer Type
chr6:g.165280018A>T COSN8314799 TCGA-A2-A3Y0-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-5p gaaATTCTTTacttccatg
 0 CAAAGAAU m7b (m6c->m7b) no TS -0.112000 0.800000
hsa-miR-3653 gaaaTTCTTAacttccatg
 1
 CUAAGAAG m6b Disrupted -0.057000 -0.032000 0.250000
hsa-miR-3658 gaaaTTCTTAActtccatg
 1
 UUUAAGAA m7b Disrupted -0.137000 -0.043000 7.100000
hsa-miR-4670-3p gaaattctTAACTTCcatg
 1
 UGAAGUUA m7b Disrupted -0.148000 no TS 4.420000
hsa-miR-548ao-5p gaaattctTTACTTCcatg
 0 AGAAGUAA m7b Created no TS -0.163000 -3.570000
hsa-miR-548ax gaaattctTTACTTCcatg
 0 AGAAGUAA m7b Created no TS -0.163000 -0.580000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
165280004 rs144098885 T T hsa-miR-187-5p
hsa-miR-221-3p
hsa-miR-222-3p
hsa-miR-548v
2
2
2
2
 tgtaTGTAGCAtg
tgtATGTAGCAtg
tgtATGTAGCAtg
tgtaTGTAGCAtg
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 -0.167
-0.387
-0.377
-0.154
C hsa-miR-5689
2
 TGTATGCAgcatg
 Created
N
 -0.39

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