SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_000065
Gene Symbol: C6
Description: Homo sapiens complement component 6 (C6), transcript variant 1, mRNA.
Gene Location: chr5(-):41142335-41213667
Browse Pathways

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr5:g.41142253A>G COSN8225229 ASHPC_0013_Pa_P [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5696 aaatgAAATGAacaggtaa
2
CUCAUUUA m6b Created -0.043000 -0.049000 -0.860000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.41142334C>T COSN2106134 RK023_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-148a-5p ctgAGAACTTggcagataa
0 AAAGUUCU m7b (m6c->m7b) no TS -0.083000 -0.020000
hsa-miR-192-3p ctgagaacTTGGCAGataa
0 CUGCCAAU m7a Created NA NA -2.140000
hsa-miR-4480 ctgagaACTTGGCagataa
0 AGCCAAGU m7b Created no TS -0.432000 -4.240000
hsa-miR-4727-5p ctgagaactTGGCAGATaa
0 AUCUGCCA m8a (m7a->m8a) no TS -0.274000 -1.680000
hsa-miR-148a-5p ctgAGAACTTggcagataa
0 AAAGUUCU m7b (m6c->m7b) no TS -0.083 -0.02
hsa-miR-192-3p ctgagaacTTGGCAGataa
0 CUGCCAAU m7a Created NA NA -2.14
hsa-miR-4480 ctgagaACTTGGCagataa
0 AGCCAAGU m7b Created no TS -0.432 -4.24
hsa-miR-4727-5p ctgagaactTGGCAGATaa
0 AUCUGCCA m8a (m7a->m8a) no TS -0.274 -1.68

Mutation Mutation ID Sample Name Cancer Type
chr5:g.41142368A>G COSN6297255 RK111_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4793-5p tgtgtataCAGGATGTcaa
1
ACAUCCUG m8a Disrupted -0.264000 no TS 0.300000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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