SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_018302
Gene Symbol:	C4orf19
Description:	Homo sapiens chromosome 4 open reading frame 19 (C4orf19), transcript variant 1, mRNA.
Gene Location:	chr4(+):37585854-37595132
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.37591312A>G			COSN6829943		RK308_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1911-3p	tctttgagcGCCTGGTaca	2	CACCAGGC	m7b	(m6c->m7b)	-0.136000	-0.365000	-0.030000
hsa-miR-3907	tctttGAGCACCTggtaca	2	AGGUGCUC	m8a	Disrupted	-0.269000	no TS	0.640000
hsa-miR-4645-5p	tctttgagcGCCTGGTaca	0	ACCAGGCA	m7a	(m6b->m7a)	NA	NA	-0.160000
hsa-miR-764	tctttgaGCACCTGgtaca	2	GCAGGUGC	m7b	Disrupted	-0.253000	no TS	0.520000

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.37591889C>T			COSN7489611		8051974		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4685-5p	atcagtgaCCCTGGatgtt	1	CCCAGGGC	m6b	Disrupted	-0.262000	-0.160000	0.410000
hsa-miR-520a-5p	atcagtgaCTCTGGAtgtt	5	CUCCAGAG	m7b	Created	-0.070000	-0.197000	-0.510000
hsa-miR-525-5p	atcagtgaCTCTGGAtgtt	5	CUCCAGAG	m7b	Created	-0.079000	-0.216000	-0.030000

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.37591980G>A			COSN6829944		RK150_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.37592107C>T			COSN6829945		RK308_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3150a-5p	cttggGAGGTTGaggcaag	0	CAACCUCG	m7a	Created	NA	NA	1.080000
hsa-miR-3150b-5p	cttggGAGGTTGaggcaag	0	CAACCUCG	m7a	Created	NA	NA	0.290000
hsa-miR-4714-3p	cttgggAGGTTGaggcaag	0	CCAACCUA	m6b	Created	no TS	0.019000	-0.260000

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.37592379G>C			COSN2027580		RK027_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-142-3p	aaagagctACACTACAaaa	0	UGUAGUGU	m8a	Created	no TS	-0.192000	-7.790000
hsa-miR-4280	aaagagCTACACTacaaaa	0	GAGUGUAG	m7b	Created	no TS	-0.112000	-11.960000
hsa-miR-142-3p	aaagagctACACTACAaaa	0	UGUAGUGU	m8a	Created	no TS	-0.192000	-7.790000
hsa-miR-4280	aaagagCTACACTacaaaa	0	GAGUGUAG	m7b	Created	no TS	-0.112000	-11.960000

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.37592540G>C			COSN9039564		AOCS-090-1-0		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-218-5p	tgaaacAAGCACAAccatt	0	UUGUGCUU	m8a	Created	no TS	-0.063000	-1.920000
hsa-miR-2355-3p	tgaaacaAGGACAAccatt	1	AUUGUCCU	m7b	Disrupted	-0.113000	no TS	1.420000
hsa-miR-323b-5p	tgaaacaagGACAACCatt	3	AGGUUGUC	m7b	(m7b->m6c)	-0.442000	-0.293000	0.780000
hsa-miR-636	tgaaaCAAGCACAaccatt	0	UGUGCUUG	m8a	Created	no TS	-0.192000	-9.320000
hsa-miR-676-3p	tgaaacaAGGACAaccatt	1	CUGUCCUA	m6b	Disrupted	-0.052000	no TS	0.980000

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.37592754G>T			COSN6829946		RK122_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3163	agaataATTTTATgtgctt	2	UAUAAAAU	m7b	Created	0.099000	0.204000	No effect
hsa-miR-4666a-3p	agaataATTGTATGtgctt	1	CAUACAAU	m8a	Disrupted	0.002000	no TS	0.010000
hsa-miR-944	agAATAATTTtatgtgctt	1	AAAUUAUU	m8a	(m7a->m8a)	0.102000	0.075000	0.090000

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.37593228A>G			COSN6829947		RK214_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-188-3p	ttcagttgTGTGGGAcgag	0	CUCCCACA	m7b	Created	no TS	-0.153000	-0.120000
hsa-miR-4433-5p	ttcagttgtGTGGGACGag	0	CGUCCCAC	m8a	(m7b->m8a)	no TS	-0.282000	-3.730000

Mutation			Mutation ID		Sample Name		Cancer Type
chr4:g.37593281A>G			COSN6829948		RK219_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4494	tgtaaaagaAGTCTGGagt	0	CCAGACUG	m7a	(m7a->m6b)	NA	NA	0.910000
hsa-miR-499b-5p	tgtaaaagAAGTCTGgagt	6	ACAGACUU	m7b	Disrupted	-0.142000	no TS	0.090000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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